{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T09:24:08Z","timestamp":1780478648374,"version":"3.54.1"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2005,1,11]],"date-time":"2005-01-11T00:00:00Z","timestamp":1105401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Proteoglycan fragments (PF) as chondroitin sulphate were monitored and compared in two groups of patients who had anterior cruciate ligament reconstruction with either patellar tendon (PT) or quadruple semitendinosus tendon (ST) autografts. There were 20 ST and 21\u00a0PT reconstructions. No difference existed between the groups in terms of associated lesion and time from injury to surgery. Synovial sample was collected at 6 weeks, 3\u00a0months and 18\u00a0months after the operation. No difference was noted between the groups at 18\u00a0months in terms of activity level and functional scores. Both groups demonstrated a sudden increase of PF at 6 weeks with respect to preoperative quantities (<jats:italic>p<\/jats:italic>&lt;0.0001). A significant decrease occurred in the PT group at 3\u00a0months (<jats:italic>p<\/jats:italic>&lt;0.008). Even at 18\u00a0months, it was significantly below the preoperative values (<jats:italic>p<\/jats:italic>&lt;0.004). However, the decrease in ST cases relative to 6 weeks was insignificant at 3\u00a0months and quantities did not drop below the preoperative levels at 18\u00a0month (<jats:italic>p<\/jats:italic>=0.79). These results confirm again a gradual decrease of PF values in PT\u2010reconstructed knees depending on time and surgery. Reconstruction with quadruple ST does not seem to have the same effect until 18\u00a0months postoperatively. Achievement of almost the same level of activity and function in both groups does not necessarily reflect the molecular status.<\/jats:p>","DOI":"10.1007\/s00167-004-0578-5","type":"journal-article","created":{"date-parts":[[2005,1,11]],"date-time":"2005-01-11T06:15:53Z","timestamp":1105424153000},"page":"385-392","source":"Crossref","is-referenced-by-count":2,"title":["Proteoglycan fragments in anterior cruciate ligament reconstructed knees: a comparative study of two different surgical techniques"],"prefix":"10.1002","volume":"13","author":[{"given":"Emin","family":"Taskiran","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology Ege University School of Medicine 35100 Bornova, \u0130zmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilek","family":"Taskiran","sequence":"additional","affiliation":[{"name":"Department of Physiology Ege University School of Medicine 35100 Bornova, \u0130zmir 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