{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T14:47:07Z","timestamp":1768315627565,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2007,8,25]],"date-time":"2007-08-25T00:00:00Z","timestamp":1188000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We analysed the morphological features of the human surgical specimens of supraspinatus tendon from patients with rotator cuff tears. Tendon samples were harvested from 31 subjects (21\u00a0men and 10 women; mean age 51 years, range 38\u201364) who underwent arthroscopic repair of a rotator cuff tear, and from five male patients who died of cardiovascular events (mean age, 69.6 years). Histological examination was performed using Haematoxylin and Eosin, Masson's Trichrome and Van Gieson's connective tissue stain. The specimens were examined twice by the same examiner under white light and polarized light microscopy. Particular effort was made to assess any evidence of the changes associated with tendinopathy. Within each specific category of tendon abnormalities, the chi\u2010square test showed significant differences between the control and ruptured tendons (<jats:italic>P<\/jats:italic> &lt; 0.05). Using the kappa statistics, the agreement between the two readings ranged from 0.57 to 0.84. We found thinning and disorientation of collagen fibres and chondroid metaplasia to be more pronounced on the articular side of the specimens from patients with rotator cuff tear (<jats:italic>P<\/jats:italic> &lt; 0.05). The present study provides a description of the histological architecture of human surgical specimens of normal supraspinatus tendon from patients with rotator cuff tears and demonstrates more frequent tendon changes on the articular side of the rotator cuff.<\/jats:p>","DOI":"10.1007\/s00167-007-0395-8","type":"journal-article","created":{"date-parts":[[2007,8,24]],"date-time":"2007-08-24T13:19:57Z","timestamp":1187961597000},"page":"1390-1394","source":"Crossref","is-referenced-by-count":77,"title":["Light microscopic histology of supraspinatus tendon ruptures"],"prefix":"10.1002","volume":"15","author":[{"given":"Umile Giuseppe","family":"Longo","sequence":"first","affiliation":[{"name":"Department of Orthopaedic and Trauma Surgery Campus Biomedico University Via Longoni, 83 00155 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Franceschi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Trauma Surgery Campus Biomedico University Via Longoni, 83 00155 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Ruzzini","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Trauma Surgery Campus Biomedico University Via Longoni, 83 00155 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla","family":"Rabitti","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology Campus Biomedico University Via Longoni, 83 00155 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Morini","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology Campus Biomedico University Via Longoni, 83 00155 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicola","family":"Maffulli","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedic Surgery University Hospital of North Staffordshire Keele University School of Medicine ST4 7LN Stoke on Trent UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Forriol","sequence":"additional","affiliation":[{"name":"Research Unit FREMAP Hospital Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Denaro","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic and Trauma Surgery Campus Biomedico University Via Longoni, 83 00155 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,8,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278\u20105919(03)00067\u2010X"},{"key":"e_1_2_9_3_1","first-page":"1","article-title":"Subcutaneous rupture of the Achilles tendon; a study of 92 cases","volume":"116","author":"Arner O","year":"1959","journal-title":"Acta Chir Scand Suppl"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(20)30586-X"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-199805000-00016"},{"key":"e_1_2_9_6_1","unstructured":"CodmanE(1934)The shoulder"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.46B2.314"},{"key":"e_1_2_9_8_1","doi-asserted-by":"crossref","unstructured":"FranceschiF LongoUG RuzziniL PapaliaR RizzelloG DenaroV(2006)To detach the long head of the biceps tendon after tenodesis or not: Outcome analysis at the 4\u2010year follow\u2010up of two different techniques.Int Orthop","DOI":"10.1007\/s00264-006-0206-8"},{"key":"e_1_2_9_9_1","doi-asserted-by":"crossref","unstructured":"FranceschiF LongoUG RuzziniL RizzelloG DenaroV(2007)Arthroscopic management of calcific tendinitis of the subscapularis tendon.Knee Surg Sports Traumatol Arthrosc (in press)","DOI":"10.1007\/s00167-007-0340-x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","unstructured":"FranceschiF RuzziniL LongoUG MartinaFM Beomonte ZobelB MaffulliN DenaroV(2007)Equivalent clinical results of arthroscopic single\u2010row and double\u2010row suture anchor repair for rotator cuff tears: a randomized controlled trial.Am J Sports Med (in press)","DOI":"10.1177\/0363546507302218"},{"key":"e_1_2_9_11_1","first-page":"162","article-title":"Shoulder impingement syndrome","volume":"269","author":"Fu FH","year":"1991","journal-title":"A critical review. 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