{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:33:24Z","timestamp":1777710804904,"version":"3.51.4"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,2,22]],"date-time":"2008-02-22T00:00:00Z","timestamp":1203638400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/2.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2008,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Osteochondral transplantation is a successful treatment for full\u2010thickness cartilage defects, which without treatment would lead to early osteoarthritis. Restoration of surface congruency and stability of the reconstruction may be jeopardized by early mobilization. To investigate the biomechanical effectiveness of osteochondral transplantation, we performed a standardized osteochondral transplantation in eight intact human cadaver knees, using three cylindrical plugs on a full\u2010thickness cartilage defect, bottomed on one condyle, unbottomed on the contralateral condyle. Surface pressure measurements with Tekscan pressure transducers were performed after five conditions. In the presence of a defect the border contact pressure of the articular cartilage defect significantly increased to 192% as compared to the initially intact joint surface. This was partially restored with osteochondral transplantation (mosaicplasty), as the rim stress subsequently decreased to 135% of the preoperative value. Following weight bearing motion two out of eight unbottomed mosaicplasties showed subsidence of the plugs according to Tekscan measurements. This study demonstrates that a three\u2010plug mosaicplasty is effective in restoring the increased border contact pressure of a cartilage defect, which may postpone the development of early osteoarthritis. Unbottomed mosaicplasties may be more susceptible for subsidence below flush level after (unintended) weight bearing motion.<\/jats:p>","DOI":"10.1007\/s00167-008-0494-1","type":"journal-article","created":{"date-parts":[[2008,2,21]],"date-time":"2008-02-21T11:38:23Z","timestamp":1203593903000},"page":"461-468","source":"Crossref","is-referenced-by-count":51,"title":["A cadaveric analysis of contact stress restoration after osteochondral transplantation of a cylindrical cartilage defect"],"prefix":"10.1002","volume":"16","author":[{"given":"Niels B.","family":"Kock","sequence":"first","affiliation":[{"name":"Orthopaedic Research Laboratory Department of Orthopaedics Radboud University Nijmegen Medical Centre P.O. Box 9101 Nijmegen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 M. H.","family":"Smolders","sequence":"additional","affiliation":[{"name":"Orthopaedic Research Laboratory Department of Orthopaedics Radboud University Nijmegen Medical Centre P.O. Box 9101 Nijmegen The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Job L. C.","family":"van Susante","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Rijnstate Hospital Postbus 9555 6800 TA Arnhem The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pieter","family":"Buma","sequence":"additional","affiliation":[{"name":"Orthopaedic Research Laboratory Department of Orthopaedics Radboud University Nijmegen Medical Centre P.O. 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