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Between October 2006 and March 2007, 23 patients underwent arthroscopic acromioplasty. A sample of at least 3\u00a0ml of fluid from the shoulder was obtained 15\u00a0min after the end of the procedure. At the same time another sample of 3\u00a0ml of the patient's venous blood was obtained as a control. The concentrations of growth factors in the fluids collected were determined using enzyme\u2010linked immunosorbent assay (ELISA). The growth factors assayed were platelet\u2010derived growth factor\u2010AB (PDGF\u2010AB), basic fibroblast growth factor basic (bFGF) and transforming growth factor beta 1 (TGF\u2010\u03b21). The concentrations of TGF\u2010\u03b21 (<jats:italic>p<\/jats:italic> = 0.0001), PDGF\u2010AB (<jats:italic>p<\/jats:italic> = 0.02), and bFGF (<jats:italic>p<\/jats:italic> &lt; 0.0001) were significantly higher in the fluid from the subacromial space than in the blood sample. There are high concentrations of several growth factors in the subacromial space after acromioplasty.<\/jats:p>","DOI":"10.1007\/s00167-008-0653-4","type":"journal-article","created":{"date-parts":[[2008,10,30]],"date-time":"2008-10-30T15:23:06Z","timestamp":1225380186000},"page":"98-101","source":"Crossref","is-referenced-by-count":33,"title":["Release of growth factors after arthroscopic acromioplasty"],"prefix":"10.1002","volume":"17","author":[{"given":"Pietro","family":"Randelli","sequence":"first","affiliation":[{"name":"Dipartimento di Scienze Medico\u2010Chirurgiche Universit\u00e0 degli Studi di Milano IRCCS Policlinico San Donato Via Morandi 30 20097 San Donato Milanese, Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrizio","family":"Margheritini","sequence":"additional","affiliation":[{"name":"Facolt\u00e0 di Scienze Motorie Universit\u00e0 di Roma Rome 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