{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T11:10:29Z","timestamp":1760872229724,"version":"build-2065373602"},"reference-count":9,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2009,3,3]],"date-time":"2009-03-03T00:00:00Z","timestamp":1236038400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We describe a case of delayed union in a tibial fracture secondary to primary hyperparathyroidism. A closed intra\u2010articular proximal tibia fracture was stabilized with a hybrid external fixator. At 5\u00a0months clinical and radiological evaluation failed to demonstrate evidence of fracture healing. Fixation was stable and inflammatory markers ruled out infection. Further questioning revealed symptoms of anorexia, nausea and constipation. Plasma biochemistry showed an elevated corrected calcium and parathyroid hormone concentration. Further investigation included a sestamibi scan which confirmed a diagnosis of hyperparathyroidism secondary to a parathyroid adenoma. Six weeks following partial parathyroidectomy the fracture site was pain free, non\u2010tender and the fracture had united radiologically. In cases of delayed\u2010union, once an infective cause has been excluded with a mechanically stable fracture, other causes of delayed union like primary hyperparathyroidism should be ruled out.<\/jats:p>","DOI":"10.1007\/s00167-009-0753-9","type":"journal-article","created":{"date-parts":[[2009,3,2]],"date-time":"2009-03-02T13:17:00Z","timestamp":1235999820000},"page":"551-554","source":"Crossref","is-referenced-by-count":8,"title":["Primary hyperparathyroidism presenting as delayed fracture union"],"prefix":"10.1002","volume":"17","author":[{"given":"P. S.","family":"Sauv\u00e9","sequence":"first","affiliation":[{"name":"Department of Trauma and Orthopaedics North Hampshire Hospitals Foundation NHS Trust Aldermaston Road RG24 9NA Basingstoke Hampshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. G. I.","family":"Suliman","sequence":"additional","affiliation":[{"name":"Department of Trauma and Orthopaedics North Hampshire Hospitals Foundation NHS Trust Aldermaston Road RG24 9NA Basingstoke Hampshire UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. D.","family":"Calder","sequence":"additional","affiliation":[{"name":"Imperial College School of Medicine London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,3,3]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.77B3.7744927"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.20388"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/1757\u20101626\u20101\u201061"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/165.7.569"},{"key":"e_1_2_5_6_1","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1097\/00003086-197705000-00030","article-title":"Delayed fracture healing in primary hyperparathyroidism","volume":"124","author":"Lancourt JE","year":"1977","journal-title":"Clin Orthop Relat Res"},{"key":"e_1_2_5_7_1","first-page":"183","volume-title":"Clinical chemistry","author":"Marshall W","year":"2000"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000093012.90435.e3"},{"key":"e_1_2_5_9_1","first-page":"194","volume-title":"Recent advances in endocrinology and metabolism (no. 1)","author":"O'Riordan JLH","year":"1978"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910213411701"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-009-0753-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00167-009-0753-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00167-009-0753-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:48:46Z","timestamp":1760870926000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/s00167-009-0753-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3,3]]},"references-count":9,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5]]}},"alternative-id":["10.1007\/s00167-009-0753-9"],"URL":"https:\/\/doi.org\/10.1007\/s00167-009-0753-9","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"type":"print","value":"0942-2056"},{"type":"electronic","value":"1433-7347"}],"subject":[],"published":{"date-parts":[[2009,3,3]]}}}