{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T23:24:17Z","timestamp":1782602657593,"version":"3.54.5"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,6]],"date-time":"2012-12-06T00:00:00Z","timestamp":1354752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study is to evaluate the safety and clinical efficacy of this novel polyurethane meniscal scaffold to treat partial meniscal loss.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Eighteen patients (11\u00a0men and 7 women, mean age: 45 years) affected by irreparable acute meniscal tears requiring partial meniscectomy or chronic prior loss of meniscal tissue were enrolled in the study. They underwent arthroscopic polyurethane meniscal scaffold implantation (13\u00a0medial and 5 lateral) and, in case of presence of other comorbidities, concurrent procedures were also performed. Patients were prospectively evaluated up to 2 years of follow\u2010up through IKDC objective, IKDC subjective, and Tegner scores. Furthermore, MRI evaluation of the meniscal scaffold was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No major adverse events were observed. A statistically significant increase in all the clinical parameters considered was found. The IKDC objective score increased from 61 % of normal or nearly normal knees at basal evaluation to 94 % at 2 years of follow\u2010up (<jats:italic>p<\/jats:italic> = 0.01). There was also a significant increase in the IKDC subjective score both at 6\u201312\u00a0months of follow\u2010up (<jats:italic>p<\/jats:italic> = 0.03 and <jats:italic>p<\/jats:italic> &lt; 0.005), which was confirmed at 24\u00a0months. The Tegner score also showed a significant increase from the pre\u2010operative level (median value 2, range 1\u20135) to final evaluation (median value 3, range 2\u20135; <jats:italic>p<\/jats:italic> = 0.005), albeit not reaching the pre\u2010injury sports activity level.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The implantation of this novel polyurethane scaffold proved to be a safe and potentially effective procedure to treat partial meniscal loss with encouraging results at short\u2010term follow\u2010up. Further high\u2010quality studies with larger numbers of patients and longer evaluation times are needed to confirm these preliminary data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Case series, Level IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-012-2328-4","type":"journal-article","created":{"date-parts":[[2012,12,5]],"date-time":"2012-12-05T16:38:19Z","timestamp":1354725499000},"page":"128-134","source":"Crossref","is-referenced-by-count":58,"title":["Biodegradable polyurethane meniscal scaffold for isolated partial lesions or as combined procedure for knees with multiple comorbidities: clinical results at 2 years"],"prefix":"10.1002","volume":"22","author":[{"given":"Elizaveta","family":"Kon","sequence":"first","affiliation":[{"name":"Nano\u2010Biotechnology Laboratory Rizzoli Orthopaedic Institute Via di Barbiano n. 1\/10 40136 Bologna 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