{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:37:13Z","timestamp":1778776633315,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T00:00:00Z","timestamp":1381536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study assessed the results of two\u2010portal knee arthroscopic synovectomy in terms of bleeding recurrence, knee function, quality of life (QOL), and radiographic staging in a prospective case series of patients with haemophilia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nine knees from eight patients (median age 16.1 years; range 9.6\u201325 years) with haemophilia and recurrent knee haemarthrosis were prospectively evaluated. Yearly recurrence of bleeding was evaluated once a year for 5 years postoperatively. Range of motion (ROM) and radiographic staging, as well as results of the short form (SF)\u201036 and subjective knee form of the International Knee Documentation Committee (IKDC) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaires, were evaluated before surgery and at the end of follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Mean bleeding recurrence was significantly reduced during the 5\u2010year follow\u2010up period. Questionnaire results showed significant improvements (IKDC <jats:italic>P<\/jats:italic> = 0.015, WOMAC <jats:italic>P<\/jats:italic> = 0.011, and SF\u201036 <jats:italic>P<\/jats:italic> = 0.023), whereas ROM was not significantly affected. Arthropathy progressed from Arnold\u2013Hilgartner radiographic stage III to stage IV (<jats:italic>P<\/jats:italic> = 0.0082).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Two\u2010portal knee arthroscopic synovectomy was effective at reducing bleeding recurrence and improving knee function and QOL in patients with haemophilia, but did not interrupt the progression of radiographic changes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Case series, Level IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-013-2706-6","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T13:53:22Z","timestamp":1381499602000},"page":"785-791","source":"Crossref","is-referenced-by-count":10,"title":["Arthroscopic partial anterior synovectomy of the knee on patients with haemophilia"],"prefix":"10.1002","volume":"23","author":[{"given":"Adriano Marques","family":"de Almeida","sequence":"first","affiliation":[{"name":"Department of Orthopedics and Traumatology S\u00e3o Paulo University Medical School Rua Dr. Ov\u00eddio Pires de Campos, 333 Cerqueira Cesar 05403\u2010010 S\u00e3o Paulo SP Brazil"},{"name":"Institute of Orthopedics and Traumatology Hospital das Cl\u00ednicas Faculty of Medicine University of S\u00e3o Paulo Rua Dr. Ovidio Pires de Campos, 333, Cerqueira C\u00e9sar 05403\u2010010 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia Uchoa","family":"de Rezende","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology S\u00e3o Paulo University Medical School Rua Dr. Ov\u00eddio Pires de Campos, 333 Cerqueira Cesar 05403\u2010010 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felippi Guizardi","family":"Cordeiro","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology S\u00e3o Paulo University Medical School Rua Dr. Ov\u00eddio Pires de Campos, 333 Cerqueira Cesar 05403\u2010010 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula Ribeiro","family":"Villa\u00e7a","sequence":"additional","affiliation":[{"name":"Department of Hematology Hemophilia Center S\u00e3o Paulo University Medical School Av Dr. Eneas de Carvalho Aguiar, 155, 1st Floor. Cerqueira C\u00e9sar 05403\u2010000 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elbio Antonio","family":"D'Amico","sequence":"additional","affiliation":[{"name":"Department of Hematology Hemophilia Center S\u00e3o Paulo University Medical School Av Dr. Eneas de Carvalho Aguiar, 155, 1st Floor. Cerqueira C\u00e9sar 05403\u2010000 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaldo Jos\u00e9","family":"Hernandez","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology S\u00e3o Paulo University Medical School Rua Dr. Ov\u00eddio Pires de Campos, 333 Cerqueira Cesar 05403\u2010010 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gilberto Luis","family":"Camanho","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology S\u00e3o Paulo University Medical School Rua Dr. Ov\u00eddio Pires de Campos, 333 Cerqueira Cesar 05403\u2010010 S\u00e3o Paulo SP Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102141.2011.08919.x"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197759030-00001"},{"key":"e_1_2_6_4_1","first-page":"143","article-title":"Brazilian\u2010portuguese version of the SF\u201036. A reliable and valid quality of life outcome measure","volume":"39","author":"Ciconelli R","year":"1999","journal-title":"Rev Bras Reumatol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/01241398\u2010200407000\u201000013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199710000-00012"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102516.2012.02790.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.12.8757"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538\u20107836.2011.04214.x"},{"key":"e_1_2_6_10_1","unstructured":"IvanovithM(2002)Brazilian\u2010portuguese translation and validation of the Western\u2010Ontario and McMaster Universities Osteoarthritis Index (WOMAC).[dissertation]. S\u00e3o Paulo: Universidade Federal de S\u00e3o Paulo"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426\u2010200309000\u201000010"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02573.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102516.2010.02435.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749\u20108063(87)80116\u20100"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749\u20108063(87)80019\u20101"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510365314"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-198668020-00006"},{"key":"e_1_2_6_18_1","first-page":"457","article-title":"Arthroscopic synovectomy in the treatment of haemophilic arthropathy: preliminary results in eight patients","volume":"15","author":"Poggini L","year":"1989","journal-title":"Ital J Orthop Traumatol"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198601000-00017"},{"key":"e_1_2_6_20_1","first-page":"345","article-title":"Articular cartilage degradation and the pathology of haemophilic arthropathy","volume":"54","author":"Rippey JJ","year":"1978","journal-title":"S Afr Med J"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e3283570f91"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086\u2010199607000\u201000003"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/201271"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102559.1999.00608.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749\u20108063(85)80012\u20108"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000208851"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2002.32621"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199210000-00027"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20102516.2007.01539.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749\u20108063(85)80013\u2010X"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.1984.tb02572.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365\u20102516.2002.00606.x"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264\u2010005\u20100666\u20102"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-013-2706-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00167-013-2706-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00167-013-2706-6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:38:36Z","timestamp":1760881116000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/s00167-013-2706-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,12]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1007\/s00167-013-2706-6"],"URL":"https:\/\/doi.org\/10.1007\/s00167-013-2706-6","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,12]]}}}