{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:59:25Z","timestamp":1783393165330,"version":"3.54.6"},"reference-count":40,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,8,1]],"date-time":"2014-08-01T00:00:00Z","timestamp":1406851200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2014,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Medial patellofemoral ligament (MPFL) reconstruction is a well\u2010established treatment option in recurrent patella dislocation. The combination with associated retropatellar cartilage lesions are severe injuries and very difficult to treat. The purpose of this study was to evaluate our clinical results of MPFL reconstruction and autologous chondrocyte implantation (ACI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirteen patients with recurrent patella dislocation were treated with a combination of MPFL reconstruction and ACI at our institution between 2010 and 2014. All patients had at least 2 patella dislocations. The posttraumatic cartilage lesions were grade IV according to the ICRS and were localized retropatellar in 8 cases and at the lateral femoral condyle in 2 cases. The mean defect size was 7.2 \u00b1 3.5\u00a0cm<jats:sup>2<\/jats:sup> (3\u201312\u00a0cm<jats:sup>2<\/jats:sup>). Subjective and objective scores were assessed before surgery and at f\/u, as well as radiologic parameters and cartilage status on magnetic resonance imaging (MRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten patients (5\u00a0male, 5 female) with a mean follow\u2010up of 2 years (minimum 1 year to 4 years) were enrolled in the study. At latest clinical follow\u2010up, all patients had a stable patella with no signs of instability and all patients showed improved subjective and objective scores. Lysholm score increased to 74.1 \u00b1 18.7 (48\u201399), KOOS score to 74.4 \u00b1 16.9 (57\u201395), IKDC subjective to 63.9 \u00b1 22.1 (34\u201393) and Kujala score to 73.8 \u00b1 25.1 (50\u2013100). The post\u2010operative modified MOCART score for quality assessment of the ACI on MRI was an average of 13.7 \u00b1 1.8 points (11\u201316), with a complete fill of the defect in 80 % of lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Medial patellofemoral ligament reconstruction with simultaneous ACI showed good clinical results in recurrent patella dislocation with traumatic cartilage lesions grade IV. No patella re\u2010dislocation occurred and the ACI was successful in 80 % of patients according to MRI. Subjective and objective scores improved but combined surgery is inferior to reports from the literature on MPFL reconstruction alone without cartilage damage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Therapeutic case series, Level IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-014-3196-x","type":"journal-article","created":{"date-parts":[[2014,7,31]],"date-time":"2014-07-31T10:31:06Z","timestamp":1406802666000},"page":"2477-2483","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Clinical outcome after medial patellofemoral ligament reconstruction and autologous chondrocyte implantation following recurrent patella dislocation"],"prefix":"10.1002","volume":"22","author":[{"given":"Rainer","family":"Siebold","sequence":"first","affiliation":[{"name":"Institute for Anatomy and Cell Biology Ruprecht\u2010Karls\u2010University Heidelberg Germany"},{"name":"HKF \u2013 Center for Hip, Knee, Foot Surgery and Sportstraumatology ATOS Klinik Bismarckstr. 9\u201015 69115 Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios","family":"Karidakis","sequence":"additional","affiliation":[{"name":"HKF \u2013 Center for Hip, Knee, Foot Surgery and Sportstraumatology ATOS Klinik Bismarckstr. 9\u201015 69115 Heidelberg Germany"},{"name":"Orthopaedic Department 251 General Air Forces Hospital Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Fernandez","sequence":"additional","affiliation":[{"name":"HKF \u2013 Center for Hip, Knee, Foot Surgery and Sportstraumatology ATOS Klinik Bismarckstr. 9\u201015 69115 Heidelberg Germany"},{"name":"Orthopaedic Department Makati Medical Center Manila Philippines"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199410063311401"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200300002-00008"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510376230"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1148\/rg.304095755"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2001.21490"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510390476"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.00633"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2010.04.005"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010008\u20100635\u20106"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513519077"},{"issue":"14","key":"e_1_2_6_12_1","first-page":"2470","article-title":"Surgical management of articular cartilage defects of the knee","volume":"92","author":"Gomoll AH","year":"2010","journal-title":"J Bone Joint Surg Am"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.J.00049"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01560215"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2006.04.006"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513498572"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749\u20108063(05)80366\u20104"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.12.004"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010012\u20102066\u20107"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513506593"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0095399703258677"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.07.004"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507306161"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511420079"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010012\u20102347\u20101"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509349605"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509357915"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1998.28.2.88"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506296415"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010012\u20101968\u20108"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010010\u20101285\u2010z"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2003.50112"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546505285584"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2008.01.042"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198509000-00007"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.J.01723"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.10.008"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010010\u20101267\u20101"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330\u2010012\u20102493\u20103"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2009.05.001"},{"key":"e_1_2_6_41_1","unstructured":"ChowS ShaoJ WangH(2008)Sample size calculations in clinical research 2nd edn.Chapman & Hall\/CRC Biostatistics Series Boca Raton Florida p100"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-014-3196-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00167-014-3196-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00167-014-3196-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T11:30:55Z","timestamp":1760873455000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/s00167-014-3196-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8]]},"references-count":40,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1007\/s00167-014-3196-x"],"URL":"https:\/\/doi.org\/10.1007\/s00167-014-3196-x","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8]]}}}