{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T12:18:24Z","timestamp":1788351504633,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T00:00:00Z","timestamp":1415318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T00:00:00Z","timestamp":1415318400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Many studies have demonstrated that injection of various growth factors including platelet\u2010derived growth factor could increase meniscal cell activity and stimulate repair. The purpose of this study was to augment repair and promote meniscal healing by the use of platelet\u2010rich plasma (PRP) within horizontal cleavage meniscal tears repaired via an open approach. The hypothesis was that the clinical outcomes and healing process would be improved using this meniscal healing augmentation technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this case\u2013control study, 34 consecutive young patients underwent an open meniscal repair to treat symptomatic Grade 2 or Grade 3 horizontal meniscal tears [median age 28 years (13\u201340)]. The median time between the onset of symptoms and surgery was 11.5\u00a0months (6\u201350). In the first group (17 consecutive patients, Group 1), a standard open meniscal repair was performed. In the second group (17 consecutive patients, Group 2), the same surgical repair was performed, but platelet\u2010rich plasma was introduced into the lesion at the end of the procedure. Clinical outcomes were evaluated using KOOS and IKDC 2000 scores. MRI was performed at 1 year after surgery for objective evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At a minimum of 24\u00a0months postoperatively (mean 32.2\u00a0months, 24\u201340), three patients underwent subsequent meniscectomy (two in Group 1, one in Group 2). The mean KOOS distribution (pain, symptoms, daily activities, sports, quality of life) was 78.4, 86.1, 93.8, 74.4, 74.6\u00a0in Group 1, and 93.3, 90.7, 97.1, 88.8, 78.3\u00a0in Group 2 (<jats:italic>p<\/jats:italic> &lt; 0.05 for pain and sports parameters). MRI revealed five cases with the complete disappearance of any hypersignal within the repaired meniscus in Group 2, and none in Group 1 (<jats:italic>p<\/jats:italic> &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Open meniscal repair of horizontal tears extending into the avascular zone was effective at midterm follow\u2010up in young patients. Clinical outcomes were slightly improved by the addition of PRP in this case\u2013control study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>III.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-014-3417-3","type":"journal-article","created":{"date-parts":[[2014,11,14]],"date-time":"2014-11-14T14:20:45Z","timestamp":1415974845000},"page":"51-58","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":124,"title":["Platelet\u2010rich plasma for open meniscal repair in young patients: Any benefit?"],"prefix":"10.1002","volume":"23","author":[{"given":"Nicolas","family":"Pujol","sequence":"first","affiliation":[{"name":"Orthopedic Department Centre Hospitalier de Versailles Versailles\u2010Saint Quentin University 177, rue de Versailles 78157 Le Chesnay France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etienne","family":"Salle De 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