{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:49:05Z","timestamp":1790660945924,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2015,3,22]],"date-time":"2015-03-22T00:00:00Z","timestamp":1426982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,3,22]],"date-time":"2015-03-22T00:00:00Z","timestamp":1426982400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>Our hypothesis was that the Achilles tendon healing process after surgical treatment would be promoted by PRP with a faster return to sports activities.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty patients with Achilles tendon rupture and surgically treated with a combined mini\u2010open and percutaneous technique were prospectively enroled in the study. Patients were alternately case\u2010by\u2010case assigned to Group A (control group; 15 patients) or Group B (study group; 15 patients). In Group B, PRP was locally infiltrated both during surgery and 14\u00a0days after surgery. Patients in both groups were followed up at 1, 3, 6 and 24\u00a0months post\u2010operatively via physical examination, VAS, FAOS and VISA\u2010A scales; ultrasonography (US) and MRI were also conducted at one and 6\u00a0months; at the 6\u2010month follow\u2010up, isokinetic and jumping capacity tests were also performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The VAS, FAOS and VISA\u2010A scale showed no difference between the two groups at 1, 3, 6 and 24\u00a0months post\u2010operatively. Isokinetic evaluation showed no differences at both angular speeds. Jumping evaluation showed no difference at 6\u00a0months. Also US evaluation showed no differences. MRI data analysis before administration of gadolinium did not reveal significant differences between the two groups. Moreover, after intravenous injection of gadolinium, patients in Group B showed signal enhancement in 30 % of patients compared to 80 % in Group A at 6\u00a0months, as indirect evidence of better tendon remodelling (<jats:italic>P<\/jats:italic> &lt; 0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A substantial equivalence in structural and functional results in Achilles tendon ruptures surgically treated with and without addition of PRP is shown by present study. Clinical results, morphological features and jumping capability were similar in both groups. The addition of PRP to the surgical treatment of Achilles tendon rupture does not appear to offer superior clinical and functional results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-015-3580-1","type":"journal-article","created":{"date-parts":[[2015,3,21]],"date-time":"2015-03-21T10:11:44Z","timestamp":1426932704000},"page":"2231-2237","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Can platelet\u2010rich plasma have a role in Achilles tendon surgical repair?"],"prefix":"10.1002","volume":"24","author":[{"given":"Angelo","family":"De Carli","sequence":"first","affiliation":[{"name":"Orthopaedic Unit \u201cKirk Kilgour\u201d Sports Injury Center S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo Maria","family":"Lanzetti","sequence":"additional","affiliation":[{"name":"Orthopaedic Unit \u201cKirk Kilgour\u201d Sports Injury Center S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Ciompi","sequence":"additional","affiliation":[{"name":"Orthopaedic Unit \u201cKirk Kilgour\u201d Sports Injury Center S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Lupariello","sequence":"additional","affiliation":[{"name":"Orthopaedic Unit \u201cKirk Kilgour\u201d Sports Injury Center S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Vadal\u00e0","sequence":"additional","affiliation":[{"name":"Orthopaedic Unit \u201cKirk Kilgour\u201d Sports Injury Center S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Argento","sequence":"additional","affiliation":[{"name":"Diagnostic Imaging Unit S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Ferretti","sequence":"additional","affiliation":[{"name":"Orthopaedic Unit \u201cKirk Kilgour\u201d Sports Injury Center S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Via di Grottarossa 1035 00189 Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. C.","family":"Vulpiani","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation Unit S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vetrano","sequence":"additional","affiliation":[{"name":"Physical Medicine and Rehabilitation Unit S. Andrea Hospital University of Rome \u201cLa Sapienza\u201d Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.orthres.2004.08.015"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/000164700317381234"},{"issue":"3","key":"e_1_2_7_4_1","first-page":"292","article-title":"Spontaneous Achilles tendon ruptures treated with a mini open technique: clinical and functional evaluation","volume":"49","author":"De Carli A","year":"2009","journal-title":"J Sports Med Phys Fitness"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354659302100516"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010007\u20100448\u2010z"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110078500600107"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/34786470"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264\u2010011\u20101431\u20103"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.77B1.7822398"},{"issue":"9","key":"e_1_2_7_11_1","first-page":"CD003674","article-title":"Surgical interventions for treating acute Achilles tendon ruptures","volume":"8","author":"Khan RJ","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1095\u20106433(02)00255\u20106"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.3928\/01477447\u201020131021\u201037"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e318260edad"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1079\u20102104(98)90029\u20104"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256\u2010200333050\u201000004"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.35.5.335"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/107110070102201004"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22199"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506294078"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510383515"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0455.2001.042003269.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.01850"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768\u2010200112000\u201000002"},{"key":"e_1_2_7_25_1","first-page":"616","article-title":"Clinical, functional and radiological results of Achilles tenorrhaphy surgically treated with mini\u2010open technique","volume":"52","author":"Vadal\u00e0 A","year":"2012","journal-title":"J Sports Med Phys Fitness"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513475345"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512466383"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.32098\/mltj.01.2014.12"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512453293"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.I.01401"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465020300041701"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-015-3580-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00167-015-3580-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00167-015-3580-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T13:08:23Z","timestamp":1760879303000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/s00167-015-3580-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,22]]},"references-count":30,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1007\/s00167-015-3580-1"],"URL":"https:\/\/doi.org\/10.1007\/s00167-015-3580-1","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,22]]}}}