{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:30:42Z","timestamp":1788348642240,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T00:00:00Z","timestamp":1468972800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee Surg Sports Traumatol Arthrosc"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s00167-016-4240-9","type":"journal-article","created":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T08:16:37Z","timestamp":1469002597000},"page":"584-594","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Does sterilization with fractionated electron beam irradiation prevent ACL tendon allograft from tissue damage?"],"prefix":"10.1002","volume":"25","author":[{"given":"T.","family":"Schmidt","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Grabau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. H.","family":"Grotewohl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Gohs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pru\u00df","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Scheffler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Hoburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,20]]},"reference":[{"key":"4240_CR1","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/j.orthres.2005.01.007","volume":"23","author":"O Akkus","year":"2005","unstructured":"Akkus O, Belaney RM, Das P (2005) Free radical scavenging alleviates the biomechanical impairment of gamma radiation sterilized bone tissue. J Orthop Res 23:838\u2013845","journal-title":"J Orthop Res"},{"key":"4240_CR2","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1177\/036354658601400603","volume":"14","author":"D Amiel","year":"1986","unstructured":"Amiel D, Kleiner JB, Akeson WH (1986) The natural history of the anterior cruciate ligament autograft of patellar tendon origin. Am J Sports Med 14:449\u2013462","journal-title":"Am J Sports Med"},{"key":"4240_CR3","doi-asserted-by":"crossref","first-page":"606","DOI":"10.2307\/3571543","volume":"22","author":"AJ Bailey","year":"1964","unstructured":"Bailey AJ, Rhodes DN, Cater CW (1964) Irradiation-induced crosslinking of collagen. Radiat Res 22:606\u2013621","journal-title":"Radiat Res"},{"key":"4240_CR4","doi-asserted-by":"crossref","first-page":"2501","DOI":"10.1177\/0363546515596406","volume":"43","author":"CR Bottoni","year":"2015","unstructured":"Bottoni CR, Smith EL, Shaha J, Shaha SS, Raybin SG, Tokish JM, Rowles DJ (2015) Autograft versus allograft anterior cruciate ligament reconstruction: a prospective, randomized clinical study with a minimum 10-year follow-up. Am J Sports Med 43:2501\u20132509","journal-title":"Am J Sports Med"},{"key":"4240_CR5","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1021\/j150453a019","volume":"51","author":"M Burton","year":"1947","unstructured":"Burton M (1947) Effects of high-energy radiation on organic compounds. J Phys Colloid Chem 51:786\u2013797","journal-title":"J Phys Colloid Chem"},{"key":"4240_CR6","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1086\/430911","volume":"41","author":"C Crawford","year":"2005","unstructured":"Crawford C, Kainer M, Jernigan D, Banerjee S, Friedman C, Ahmed F, Archibald LK (2005) Investigation of postoperative allograft associated infections in patients who underwent musculoskeletal allograft implantation. Clin Infect Dis 41:195\u2013200","journal-title":"Clin Infect Dis"},{"key":"4240_CR7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/s10561-005-0338-x","volume":"6","author":"A Dziedzic-Goclawska","year":"2005","unstructured":"Dziedzic-Goclawska A, Kaminski A, Uhrynowska-Tyszkiewicz I, Stachowicz W (2005) Irradiation as a safety procedure in tissue banking. Cell Tissue Bank 6:201\u2013219","journal-title":"Cell Tissue Bank"},{"key":"4240_CR8","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.2106\/JBJS.L.00841","volume":"96","author":"EY Elenes","year":"2014","unstructured":"Elenes EY, Hunter SA (2014) Soft-tissue allografts terminally sterilized with an electron beam are biomechanically equivalent to aseptic, nonsterilized tendons. J Bone Joint Surg Am 96:1321\u20131326","journal-title":"J Bone Joint Surg Am"},{"key":"4240_CR9","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.2106\/00004623-199407000-00011","volume":"76","author":"BM Fideler","year":"1994","unstructured":"Fideler BM, Vangsness CT Jr, Moore T, Li Z, Rasheed S (1994) Effects of gamma irradiation on the human immunodeficiency virus. A study in frozen human bone-patellar ligament-bone grafts obtained from infected cadavera. J Bone Joint Surg Am 76:1032\u20131035","journal-title":"J Bone Joint Surg Am"},{"key":"4240_CR10","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1177\/0363546511426088","volume":"40","author":"JW Genuario","year":"2012","unstructured":"Genuario JW, Faucett SC, Boublik M, Schlegel TF (2012) A cost-effectiveness analysis comparing 3 anterior cruciate ligament graft types: bone-patellar tendon-bone autograft, hamstring autograft, and allograft. Am J Sports Med 40:307\u2013314","journal-title":"Am J Sports Med"},{"key":"4240_CR11","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s004020050231","volume":"117","author":"MJ Goertzen","year":"1998","unstructured":"Goertzen MJ, Buitkamp J, Clahsen H, Mollmann M (1998) Cell survival following bone-anterior cruciate ligament-bone allograft transplantation: DNA fingerprints, segregation, and collagen morphological analysis of multiple markers in the canine model. Arch Orthop Trauma Surg 117:208\u2013214","journal-title":"Arch Orthop Trauma Surg"},{"key":"4240_CR12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.2106\/00004623-199502000-00006","volume":"77","author":"MJ Goertzen","year":"1995","unstructured":"Goertzen MJ, Clahsen H, Burrig KF, Schulitz KP (1995) Sterilisation of canine anterior cruciate allografts by gamma irradiation in argon. Mechanical and neurohistological properties retained one year after transplantation. J Bone Joint Surg Br 77:205\u2013212","journal-title":"J Bone Joint Surg Br"},{"key":"4240_CR13","doi-asserted-by":"crossref","first-page":"1955","DOI":"10.1007\/s00167-011-1518-9","volume":"19","author":"A Hoburg","year":"2011","unstructured":"Hoburg A, Keshlaf S, Schmidt T, Smith M, Gohs U, Perka C, Pruss A, Scheffler S (2011) Fractionation of high-dose electron beam irradiation of BPTB grafts provides significantly improved viscoelastic and structural properties compared to standard gamma irradiation. Knee Surg Sports Traumatol Arthrosc 19:1955\u20131961","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"4240_CR14","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s10561-014-9461-x","volume":"16","author":"A Hoburg","year":"2015","unstructured":"Hoburg A, Keshlaf S, Schmidt T, Smith M, Gohs U, Perka C, Pruss A, Scheffler S (2015) High-dose electron beam sterilization of soft tissue grafts maintains significantly improved biomechanical properties compared to standard gamma treatment. Cell Tissue Bank 16:219\u2013226","journal-title":"Cell Tissue Bank"},{"key":"4240_CR15","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1177\/0363546509361161","volume":"38","author":"AT Hoburg","year":"2010","unstructured":"Hoburg AT, Keshlaf S, Schmidt T, Smith M, Gohs U, Perka C, Pruss A, Scheffler S (2010) Effect of electron beam irradiation on biomechanical properties of patellar tendon allografts in anterior cruciate ligament reconstruction. Am J Sports Med 38:1134\u20131140","journal-title":"Am J Sports Med"},{"key":"4240_CR16","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s001670050112","volume":"7","author":"J Kartus","year":"1999","unstructured":"Kartus J, Magnusson L, Stener S, Brandsson S, Eriksson BI, Karlsson J (1999) Complications following arthroscopic anterior cruciate ligament reconstruction. A 2\u20135-year follow-up of 604 patients with special emphasis on anterior knee pain. Knee Surg Sports Traumatol Arthrosc 7:2\u20138","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"4240_CR17","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1053\/jars.2001.28979","volume":"17","author":"J Kartus","year":"2001","unstructured":"Kartus J, Movin T, Karlsson J (2001) Donor-site morbidity and anterior knee problems after anterior cruciate ligament reconstruction using autografts. Arthroscopy 17:971\u2013980","journal-title":"Arthroscopy"},{"key":"4240_CR18","doi-asserted-by":"crossref","first-page":"559","DOI":"10.5435\/00124635-200810000-00001","volume":"16","author":"TE Mroz","year":"2008","unstructured":"Mroz TE, Joyce MJ, Steinmetz MP, Lieberman IH, Wang JC (2008) Musculoskeletal allograft risks and recalls in the United States. J Am Acad Orthop Surg 16:559\u2013565","journal-title":"J Am Acad Orthop Surg"},{"key":"4240_CR19","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1177\/0363546513518004","volume":"43","author":"SS Park","year":"2015","unstructured":"Park SS, Dwyer T, Congiusta F, Whelan DB, Theodoropoulos J (2015) Analysis of irradiation on the clinical effectiveness of allogenic tissue when used for primary anterior cruciate ligament reconstruction. Am J Sports Med 43:226\u2013235","journal-title":"Am J Sports Med"},{"key":"4240_CR20","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1006\/biol.2002.0326","volume":"30","author":"A Pruss","year":"2002","unstructured":"Pruss A, Kao M, Gohs U, Koscielny J, von Versen R, Pauli G (2002) Effect of gamma irradiation on human cortical bone transplants contaminated with enveloped and non-enveloped viruses. Biologicals 30:125\u2013133","journal-title":"Biologicals"},{"key":"4240_CR21","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1055\/s-2007-965134","volume":"39","author":"A Pruss","year":"2007","unstructured":"Pruss A, von Versen R (2007) Influence of European regulations on quality, safety and availability of cell and tissue allografts in Germany. Handchir Mikrochir Plast Chir 39:81\u201387","journal-title":"Handchir Mikrochir Plast Chir"},{"key":"4240_CR22","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4103\/0970-9290.131142","volume":"25","author":"J Raviraj","year":"2014","unstructured":"Raviraj J, Bokkasam VK, Kumar VS, Reddy US, Suman V (2014) Radiosensitizers, radioprotectors, and radiation mitigators. Indian J Dent Res 25:83\u201390","journal-title":"Indian J Dent Res"},{"key":"4240_CR23","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/j.arthro.2005.05.008","volume":"21","author":"S Scheffler","year":"2005","unstructured":"Scheffler S, Chwastek H, Schonfelder V, Unterhauser F, Hunt P, Weiler A (2005) The impact of radiofrequency shrinkage on the mechanical and histologic properties of the elongated anterior cruciate ligament in a sheep model. Arthroscopy 21:923\u2013933","journal-title":"Arthroscopy"},{"key":"4240_CR24","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1007\/s11999-008-0288-2","volume":"466","author":"SU Scheffler","year":"2008","unstructured":"Scheffler SU, Gonnermann J, Kamp J, Przybilla D, Pruss A (2008) Remodeling of ACL allografts is inhibited by peracetic acid sterilization. Clin Orthop Relat Res 466:1810\u20131818","journal-title":"Clin Orthop Relat Res"},{"key":"4240_CR25","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.arthro.2007.10.011","volume":"24","author":"SU Scheffler","year":"2008","unstructured":"Scheffler SU, Schmidt T, Gangey I, Dustmann M, Unterhauser F, Weiler A (2008) Fresh-frozen free-tendon allografts versus autografts in anterior cruciate ligament reconstruction: delayed remodeling and inferior mechanical function during long-term healing in sheep. Arthroscopy 24:448\u2013458","journal-title":"Arthroscopy"},{"key":"4240_CR26","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1007\/s00167-008-0560-8","volume":"16","author":"SU Scheffler","year":"2008","unstructured":"Scheffler SU, Unterhauser FN, Weiler A (2008) Graft remodeling and ligamentization after cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 16:834\u2013842","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"4240_CR27","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1007\/s10561-011-9289-6","volume":"13","author":"T Schmidt","year":"2012","unstructured":"Schmidt T, Hoburg A, Broziat C, Smith MD, Gohs U, Pruss A, Scheffler S (2012) Sterilization with electron beam irradiation influences the biomechanical properties and the early remodeling of tendon allografts for reconstruction of the anterior cruciate ligament (ACL). Cell Tissue Bank 13:387\u2013400","journal-title":"Cell Tissue Bank"},{"key":"4240_CR28","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000336380","volume":"39","author":"T Schmidt","year":"2012","unstructured":"Schmidt T, Hoburg AT, Gohs U, Schumann W, Sim-Brandenburg JW, Nitsche A, Scheffler S, Pruss A (2012) Inactivation effect of standard and fractionated electron beam irradiation on enveloped and non-enveloped viruses in a tendon transplant model. Transfus Med Hemother 39:29\u201335","journal-title":"Transfus Med Hemother"},{"key":"4240_CR29","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1177\/0363546506288851","volume":"34","author":"HE Schwartz","year":"2006","unstructured":"Schwartz HE, Matava MJ, Proch FS, Butler CA, Ratcliffe A, Levy M, Butler DL (2006) The effect of gamma irradiation on anterior cruciate ligament allograft biomechanical and biochemical properties in the caprine model at time zero and at 6\u00a0months after surgery. Am J Sports Med 34:1747\u20131755","journal-title":"Am J Sports Med"},{"key":"4240_CR30","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1007\/s11999-008-0301-9","volume":"466","author":"A Seto","year":"2008","unstructured":"Seto A, Gatt CJ Jr, Dunn MG (2008) Radioprotection of tendon tissue via crosslinking and free radical scavenging. Clin Orthop Relat Res 466:1788\u20131795","journal-title":"Clin Orthop Relat Res"},{"key":"4240_CR31","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1007\/s11999-009-0934-3","volume":"467","author":"A Seto","year":"2009","unstructured":"Seto A, Gatt CJ Jr, Dunn MG (2009) Improved tendon radioprotection by combined cross-linking and free radical scavenging. Clin Orthop Relat Res 467:2994\u20133001","journal-title":"Clin Orthop Relat Res"},{"key":"4240_CR32","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s10561-013-9385-x","volume":"14","author":"AU Seto","year":"2013","unstructured":"Seto AU, Culp BM, Gatt CJ Jr, Dunn M (2013) Radioprotection provides functional mechanics but delays healing of irradiated tendon allografts after ACL reconstruction in sheep. Cell Tissue Bank 14:655\u2013665","journal-title":"Cell Tissue Bank"},{"key":"4240_CR33","doi-asserted-by":"crossref","first-page":"2696","DOI":"10.1177\/0363546515589168","volume":"43","author":"SG Tejwani","year":"2015","unstructured":"Tejwani SG, Chen J, Funahashi TT, Love R, Maletis GB (2015) Revision risk after allograft anterior cruciate ligament reconstruction: association with graft processing techniques, patient characteristics, and graft type. Am J Sports Med 43:2696\u20132705","journal-title":"Am J Sports Med"},{"key":"4240_CR34","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1177\/230949901402200128","volume":"22","author":"J Wee","year":"2014","unstructured":"Wee J, Lee KT (2014) Graft infection following arthroscopic anterior cruciate ligament reconstruction: a report of four cases. J Orthop Surg 22:111\u2013117","journal-title":"J Orthop Surg"},{"key":"4240_CR35","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.jbiomech.2012.11.049","volume":"46","author":"W Wei","year":"2013","unstructured":"Wei W, Liu Y, Yang X, Tian S, Liu C, Zhang Y, Xu Z, Hu B, Tian Z, Sun K (2013) Fractionation of 50\u00a0kGy electron beam irradiation: effects on biomechanics of human flexor digitorum superficialis tendons treated with ascorbate. J Biomech 46:658\u2013661","journal-title":"J Biomech"},{"issue":"1","key":"4240_CR36","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.arthro.2015.07.027","volume":"32","author":"C Zeng","year":"2016","unstructured":"Zeng C, Gao SG, Li H, Yang T, Luo W, Li YS, Lei GH (2016) Autograft versus allograft in anterior cruciate ligament reconstruction: a meta-analysis of randomized controlled trials and systematic review of overlapping systematic reviews. Arthroscopy 32(1):153\u2013163e18","journal-title":"Arthroscopy"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-016-4240-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00167-016-4240-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-016-4240-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-016-4240-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,15]],"date-time":"2023-12-15T19:22:41Z","timestamp":1702668161000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00167-016-4240-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7,20]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["4240"],"URL":"https:\/\/doi.org\/10.1007\/s00167-016-4240-9","relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7,20]]}}}