{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T19:14:37Z","timestamp":1773602077400,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2018,6,2]],"date-time":"2018-06-02T00:00:00Z","timestamp":1527897600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2018,6,2]],"date-time":"2018-06-02T00:00:00Z","timestamp":1527897600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2018,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The aim of this study was to assess the progression of radiological cartilage changes and to document the functional, long\u2010term results during a follow\u2010up of 10 years after osteoautograft transplantation (OAT) knee surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was a retrospective analysis of all patients who underwent OAT at Turku University Hospital from 1999 to 2007. Pre\u2010 and postoperative cartilage changes were estimated based on standardised radiographs. The extent of osteoarthritis (OA) was graded according to the Kellgren\u2013Lawrence scale. Clinical outcomes were evaluated with the Knee Injury and Osteoarthritis Outcome Score (KOOS) questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 60 patients (64\u00a0knees) with a median age of 30 years (range 14\u201362) were included. The median follow\u2010up was 140\u00a0months (range 47\u2013205). Of the 64\u00a0knees examined, 14 (22%) had a traumatic chondral lesion and 50 (78%) had osteochondritis dissecans (OCD). Preoperatively, 71% of the patients had Kellgren\u2013Lawrence grades of 0\u20131; during the follow\u2010up period, 50% of the patients showed radiographical progression of OA. OA progressed most significantly in patients with normal preoperative Kellgren\u2013Lawrence grades (<jats:italic>p<\/jats:italic>\u2009=\u20090.0003). Patients with no progression in joint space narrowing had statistically significantly better overall KOOS (<jats:italic>p<\/jats:italic>\u2009=\u20090.02) than patients whose Kellgren\u2013Lawrence grades worsened. Patients with defect sizes\u2009&gt;\u20093.0\u00a0cm<jats:sup>2<\/jats:sup> scored statistically significantly better in all subscales than patients with smaller defect sizes (<jats:italic>p<\/jats:italic>\u2009=\u20090.02). Patients with OCD had statistically significantly better KOOS than patients with chondral defects (<jats:italic>p<\/jats:italic>\u2009=\u20090.008).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>OAT surgery for treating patients with cartilage defects of the knee had good clinical results after a mean follow\u2010up of 11 years. Radiological analyses revealed a progression of cartilage degeneration in 50% of the operated knees. Patients with no progression of the degenerative changes scored statistically significantly better on the KOOS self\u2010assessment test. These results indicate that OAT surgery appears to be a reasonable therapeutic option to restore knee function in patients with cartilage lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-018-4995-2","type":"journal-article","created":{"date-parts":[[2018,6,2]],"date-time":"2018-06-02T05:01:05Z","timestamp":1527915665000},"page":"3560-3565","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Favourable long\u2010term functional and radiographical outcome after osteoautograft transplantation surgery of the knee: a minimum 10\u2010year follow\u2010up"],"prefix":"10.1002","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1330-7418","authenticated-orcid":false,"given":"Elina","family":"Ekman","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery, Turku University Hospital University of Turku Kiinamyllynkatu 4\u20108 20521 Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keijo","family":"M\u00e4kel\u00e4","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery, Turku University Hospital University of Turku Kiinamyllynkatu 4\u20108 20521 Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ia","family":"Kohonen","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Medical Imaging Centre of Southwest Finland Turku University Hospital Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ari","family":"Hiltunen","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Orthopaedics Terveystalo\u2010Pulssi Hospital Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ari","family":"It\u00e4l\u00e4","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Orthopaedics Terveystalo\u2010Pulssi Hospital Turku Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,6,2]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354659702500617"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2015.06.001"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2014.10.001"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546512458763"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2005.06.018"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b013e3181b8f6c7"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546504263234"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546509360405"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623\u2010200300002\u201000004"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514562174"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.K.00815"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2010.519166"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546507305455"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.D.02846"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.2174\/1874325001004010111"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2006.11.011"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2015.11.037"},{"key":"e_1_2_9_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107525\u20101\u201017"},{"key":"e_1_2_9_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546517699846"},{"key":"e_1_2_9_21_2","first-page":"208","article-title":"Osteochondral 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