{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,19]],"date-time":"2026-07-19T23:37:13Z","timestamp":1784504233975,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>This study aimed to evaluate graft survivorship according to the size and location of chondral defects and its effect on clinical outcomes after meniscal allograft transplantation (MAT). It was hypothesized that large chondral defects would be associated with inferior outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent lateral MAT with fresh\u2010frozen allografts between 2007 and 2016 were retrospectively reviewed. The inclusion criteria were patients with femoral or tibial chondral defects (International Cartilage Repair Society grade 4) who were followed up more than 2 years with 3.0\u2010T magnetic resonance imaging (MRI) scans. Maximal lesion diameter and location were assessed on MRI. The patients were divided into two groups, with chondral defects of\u2009&lt;\u20093 and\u2009\u2265\u20093\u00a0cm<jats:sup>2<\/jats:sup> on the tibial side. Graft survivorship was compared between the two groups. Graft failure was defined as revisional MAT, meniscal tear or meniscectomy greater than one\u2010third of the allograft on MRI. Clinical outcomes were evaluated using the modified Lysholm score.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010eight knees in 26 patients (mean age 37.4\u2009\u00b1\u200910.3 years) with a mean follow\u2010up of 3.6\u2009\u00b1\u20091.0 (range 2.0\u20135.4) years were identified. Nineteen knees in 17 patients had both femoral and tibial chondral defects, 7\u00a0knees in 7 patients had only femoral chondral defects, and 2\u00a0knees in 2 patients had only tibial chondral defects. The mean preoperative femoral and tibial chondral defect sizes were 1.7\u2009\u00b1\u20091.2 and 3.0\u2009\u00b1\u20091.4\u00a0cm<jats:sup>2<\/jats:sup>, respectively. Among the seven graft failures, no graft failure occurred in the cases with tibial chondral defects of\u2009&lt;\u20093\u00a0cm<jats:sup>2<\/jats:sup>. Tibial chondral defects of\u2009\u2265\u20093\u00a0cm<jats:sup>2<\/jats:sup> were significantly associated with graft failure (<jats:italic>P<\/jats:italic>\u2009=\u20090.004; odds ratio 28.3; 95% confidence interval 2.5\u20134006.7). Defects of\u2009&lt;\u20093\u00a0cm<jats:sup>2<\/jats:sup> were located primarily in the posterior aspect of the lateral tibial plateau, and most lesions were covered by allograft (7\/9, 77.8%). The modified Lysholm scores significantly improved irrespective of chondral defects size (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Larger chondral defects, more than 3\u00a0cm<jats:sup>2<\/jats:sup> on the tibial side, were associated with inferior graft survivorship but did not influence the clinical outcomes after MAT at the 3.6\u2010year follow\u2010up. Chondral defect location was associated with defect size.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-019-05713-x","type":"journal-article","created":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T05:17:55Z","timestamp":1568956675000},"page":"82-89","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Large chondral defect not covered by meniscal allograft is associated with inferior graft survivorship after lateral meniscal allograft transplantation"],"prefix":"10.1002","volume":"29","author":[{"given":"Jun\u2010Gu","family":"Park","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery, Asan Medical Center University of Ulsan College of Medicine 88, Olympic\u2010ro 43\u2010gil, Songpa\u2010gu 05505 Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1787-1139","authenticated-orcid":false,"given":"Seong\u2010Il","family":"Bin","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery, Asan Medical Center University of Ulsan College of Medicine 88, Olympic\u2010ro 43\u2010gil, Songpa\u2010gu 05505 Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong\u2010Min","family":"Kim","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery, Asan Medical Center University of Ulsan College of Medicine 88, Olympic\u2010ro 43\u2010gil, Songpa\u2010gu 05505 Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bum\u2010Sik","family":"Lee","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery, Asan Medical Center University of Ulsan College of Medicine 88, Olympic\u2010ro 43\u2010gil, Songpa\u2010gu 05505 Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang\u2010Min","family":"Lee","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopedic Surgery Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine Yangsan Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oh\u2010Jin","family":"Kwon","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery, Asan Medical Center University of Ulsan College of Medicine 88, Olympic\u2010ro 43\u2010gil, Songpa\u2010gu 05505 Seoul Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gi\u2010Woon","family":"Yoon","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery, Asan Medical Center University of Ulsan College of Medicine 88, Olympic\u2010ro 43\u2010gil, Songpa\u2010gu 05505 Seoul Republic of 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March 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"11 September 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 September 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest in the authorship and publication of this contribution.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethical approval for the present study was obtained from the institutional review board of Asan Medical Center (AMC IRB No. 2018-1237).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}