{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T22:16:11Z","timestamp":1777414571854,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the clinical outcomes and survival at long\u2010term between hybrid and cemented primary total knee arthroplasty (TKA). A better clinical outcome and survival following a follow\u2010up as long as 15 years with the use of hybrid fixation as compared with cemented fixation was hypothesized.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Case\u2013control study of 126 patients with a mean age of 62.4 years who underwent hybrid TKA matched with 126 patients underwent cemented TKA. Clinical outcome was assessed by the Knee Society scores (KSS) and reduced Western Ontario and MacMaster Universities questionnaire (WOMAC). Radiological assessment was made by the Knee Society method.\n<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean follow\u2010up was 15.7 (range 15\u201317) years. At the final follow\u2010up, clinical scores were significantly better in the hybrid group, although the differences were not clinically relevant. Revisions for all reasons were performed in five knees in the hybrid group and 15\u00a0knees in the cemented group (<jats:italic>p<\/jats:italic>\u2009=\u20090.033). In the hybrid group, there was one aseptic femoral loosening and no aseptic tibial loosening. In the cemented group, the main reasons for aseptic revisions were polyethylene wear (six knees) and tibial loosening (four knees). Cemented fixation was a significant risk factor for aseptic revision (hazard ratio 2.3; 95% CI 1.3\u20133.7%; <jats:italic>p<\/jats:italic>\u2009=\u20090.004). Survival at 15 years for aseptic reasons was 96.5% (95% CI 93.4\u201398.7%) in hybrid groups and 90.3% (95% CI 88.7\u201393.9%) in cemented group (<jats:italic>p<\/jats:italic>\u2009=\u20090.020).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>After a minimum follow\u2010up of 15 years, hybrid fixation of primary TKA for osteoarthritis provide significantly higher clinical benefits compared with cemented fixation, but the differences were not clinically relevant. Hybrid fixation provides longer overall survival, although the femoral component survival was similar between groups.\n<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>III.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-020-06028-y","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T06:04:01Z","timestamp":1588053841000},"page":"832-837","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Better clinical outcomes and overall higher survival with hybrid versus cemented primary total knee arthroplasty: a minimum 15 years follow\u2010up"],"prefix":"10.1002","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4798-2702","authenticated-orcid":false,"given":"Alejandro","family":"Lizaur\u2010Utrilla","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery Elda University Hospital Ctra Elda\u2010Sax s\/n, Elda 03600 Alicante Spain"},{"name":"<!--<label>2<\/label>--> Department of Traumatology and Orthopaedics Miguel Hernandez University Avda Universidad s\/n, San Juan de Alicante 03202 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fancisco A.","family":"Miralles\u2010Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery Elda University Hospital Ctra Elda\u2010Sax s\/n, Elda 03600 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matias","family":"Ruiz\u2010Lozano","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery Elda University Hospital Ctra Elda\u2010Sax s\/n, Elda 03600 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Gonz\u00e1lez\u2010Parre\u00f1o","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery Elda University Hospital Ctra Elda\u2010Sax s\/n, Elda 03600 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Alonso\u2010Montero","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Traumatology and Orthopaedics Miguel Hernandez University Avda Universidad s\/n, San Juan de Alicante 03202 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando A.","family":"Lopez\u2010Prats","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Traumatology and Orthopaedics Miguel Hernandez University Avda Universidad s\/n, San Juan de Alicante 03202 Alicante Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,4,28]]},"reference":[{"key":"e_1_2_8_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2017.06.043"},{"key":"e_1_2_8_3_2","first-page":"1833","article-title":"Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip and the knee","volume":"15","author":"Bellamy N","year":"1988","journal-title":"J 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February 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 April 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was approved by the Institutional Review Board of Elda University Hospital (Miguel Hernandez University), ID number PI2019-021.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the 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