{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T11:50:33Z","timestamp":1793620233152,"version":"4.5.0"},"reference-count":35,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:00:00Z","timestamp":1598572800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>(1) To determine the rate of return to play following autologous osteochondral transplantation (AOT) for osteochondral lesions of the talus (OLT) and (2) report subsequent rehabilitation protocols.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A systematic review of the PubMed, Embase, and The Cochrane Library databases was performed according to the PRISMA guidelines based on specific eligibility criteria. Return to play data was meta\u2010analysed and subsequent rehabilitation protocols were summarised. Level of evidence and quality of evidence (Zaman\u2019s criteria) were also evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Nine studies that totalled 205 ankles were included for review. The mean follow\u2010up was 44.4 \u00b1 25.0 (range 16\u201384) months. The mean OLT size was 135.4\u2009\u00b1\u200956.4\u00a0mm\n                      <jats:sup>2<\/jats:sup>\n                      . The mean time to return to play was 5.8\u2009\u00b1\u20092.6\u00a0months. The mean rate of return to play was 86.3% (range 50\u201395.2%), with 81.8% of athletes returning to pre\u2010injury status. Based on the fixed\u2010effect model, the rate of return to play was 84.07%. Significant correlation was found between increase age and decrease rate of return to play (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.362,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.00056). There was no correlation between OLT sizes and rate of return to play (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.140,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.023). The most common time to ankle motion post\u2010surgery was immediately and the most common time to full weight\u2010bearing was 12 weeks.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This systematic review indicated a high rate of return to play following AOT in the athletic population. Size of OLT was not found to be a predictor of return to play, whereas advancing age was a predictor. Rehabilitation protocols were largely inconsistent and were primarily based on individual surgeon protocols. However, the included studies were of low level and quality of evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of evidence<\/jats:title>\n                    <jats:p>Level IV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00167-020-06216-w","type":"journal-article","created":{"date-parts":[[2020,8,28]],"date-time":"2020-08-28T00:25:17Z","timestamp":1598574317000},"page":"1554-1561","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Autologous osteochondral transplantation for osteochondral lesions of the talus: high rate of return to play in the athletic population"],"prefix":"10.1002","volume":"29","author":[{"given":"Dexter","family":"Seow","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> NYU Langone Health, NYU Langone Orthopedic Hospital 171 Delancey Street 10002 New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiharu","family":"Shimozono","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> NYU Langone Health, NYU Langone Orthopedic Hospital 171 Delancey Street 10002 New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna L.","family":"Gianakos","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Jersey City Medical Center \u2013 RWJ Barnabas Health Jersey City NJ USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenio","family":"Chiarello","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> ULSS3 Serenissima, Ospedale dell\u2019Angelo, Orthopaedics and Traumatology Venice Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathaniel","family":"Mercer","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> NYU Langone Health, NYU Langone Orthopedic Hospital 171 Delancey Street 10002 New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eoghan T.","family":"Hurley","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> NYU Langone Health, NYU Langone Orthopedic Hospital 171 Delancey Street 10002 New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7258-6528","authenticated-orcid":false,"given":"John G.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> NYU Langone Health, NYU Langone Orthopedic Hospital 171 Delancey Street 10002 New York NY 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March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors report the following potential conflicts of interest or sources of funding: J.G.K. receives support from Ohnell Family Foundation and Mr. and Mrs. Michael J. Levitt.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This manuscript is a systematic review and meta-analysis, and does not contain any studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}