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However, one\u2010third of patients experience continuous pain postoperatively, which is thought to be related to persistent maltracking of the patella and altered femoro\u2010tibial kinematics. Therefore, the aim of the present study was to simultaneously assess femoro\u2010tibial and patello\u2010femoral kinematics and identify the influence of arthroscopic LRR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixteen healthy volunteers and 12 patients with unilateral, isolated LRT were prospectively included. Open MRI scans with and without isometric quadriceps contraction were performed in 0\u00b0, 30\u00b0 and 90\u00b0 of knee flexion preoperatively and at 12\u00a0months after surgery. Patellar shift, tilt angle, patello\u2010femoral contact area and magnitude of femoro\u2010tibial rotation were calculated by digital image processing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Postoperatively, patellar shift was significantly reduced at 90\u00b0 of knee flexion compared to preoperative values. The postoperative patellar tilt angle was found to be significantly smaller at 30\u00b0 of knee flexion compared to that preoperatively. Isometric muscle contractions did not considerably influence patellar shift or tilt in either group. The patello\u2010femoral contact area increased after LRR over the full range of motion (ROM), with significant changes at 0\u00b0 and 90\u00b0. Regarding femoro\u2010tibial kinematics, significantly increased femoral internal rotation at 0\u00b0 was observed in the patient group preoperatively, whereas the magnitude of rotation at 90\u00b0 of knee flexion was comparable to that of healthy individuals. The pathologically increased femoral internal rotation at 30\u00b0 without muscular activity could be significantly decreased by LRR. With isometric quadriceps contraction no considerable improvement of femoral internal rotation could be achieved by LRR at 30\u00b0 of knee flexion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Patello\u2010femoral and femoro\u2010tibial joint kinematics could be improved, making LRR a viable surgical option in carefully selected patients with isolated LRT. However, pathologically increased femoral internal rotation during early knee flexion remained unaffected by LRR and thus potentially accounts for persistent pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>II.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-021-06434-w","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T05:03:33Z","timestamp":1611637413000},"page":"791-799","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Arthroscopic lateral retinacular release improves patello\u2010femoral and femoro\u2010tibial kinematics in patients with isolated lateral retinacular tightness"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8867-2973","authenticated-orcid":false,"given":"Florian","family":"Pohlig","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic 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