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However, the specificity of these target values for young athletes after ACL reconstruction is unclear. The purpose of this analysis was to (1) derive age\u2010 and activity\u2010relevant KOOS functional recovery target values from uninjured young athlete data and (2) determine clinical measures at the time of RTS clearance associated with meeting the newly\u2010derived functional recovery target values in young athletes following ACLR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Two hundred and twenty\u2010two young athletes (56 uninjured controls, 17.2\u2009\u00b1\u20092.4 years, 73% female; 166 after ACL reconstruction, 16.9\u2009\u00b1\u20092.2 years, 68% female) were included in this cross\u2010sectional analysis from a larger cohort study. Uninjured control participants completed the KOOS, and functional recovery target values were defined as the lower bound of the 95% confidence interval for KOOS subscales. ACL reconstruction participants completed testing within 4 weeks of return\u2010to\u2010sport clearance, including the KOOS, single\u2010leg hop tests, and isometric quadriceps strength. In ACL reconstruction participants, logistic regression was used to determine predictors of meeting all KOOS functional recovery target values (primary outcome) among demographic\/injury, hop, and strength data (<jats:italic>\u03b1<\/jats:italic>\u2009\u2264\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>KOOS functional recovery target values for each subscale from uninjured athlete data were: Pain\u2009\u2265\u200994, Symptoms\u2009\u2265\u200992, Activities of Daily Living\u2009\u2265\u200997, Sport\u2009\u2265\u200992, and Quality\u2010of\u2010Life\u2009\u2265\u200992. At the time of return\u2010to\u2010sport clearance, ACL reconstruction participants met the KOOS functional recovery targets in the following proportions: Pain, 63%; Symptoms, 42%; Activities of Daily Living, 80%; Sport, 45%; Quality\u2010of\u2010Life, 24%; overall functional recovery (met all subscale targets), 17%. In ACL reconstruction participants, significant predictors of overall functional recovery (primary outcome) were: younger age, hamstring graft, pediatric ACL reconstruction, quadriceps strength limb\u2010symmetry index\u2009&gt;\u200990%, single\u2010hop limb\u2010symmetry index\u2009&gt;\u200990%, and crossover\u2010hop limb\u2010symmetry index\u2009&gt;\u200990%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>KOOS functional recovery target values derived from uninjured young athletes were higher than those previously reported. Small proportions of young athletes following recent RTS clearance after ACLR met these newly\u2010derived functional recovery target values, and factors associated with meeting functional recovery target values included younger age, hamstring autograft and pediatric ACLR, and having\u2009&gt;\u200990% LSI for quadriceps strength and single\u2010leg hop tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>I.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-021-06769-4","type":"journal-article","created":{"date-parts":[[2021,11,11]],"date-time":"2021-11-11T09:03:55Z","timestamp":1636621435000},"page":"3268-3276","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Few young athletes meet newly derived age\u2010 and activity\u2010relevant functional recovery targets after ACL reconstruction"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8533-3661","authenticated-orcid":false,"given":"Matthew P.","family":"Ithurburn","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> American Sports Medicine Institute 833 St. Vincent\u2019s Drive, Suite 205 Birmingham AL USA"},{"name":"<!--<label>2<\/label>--> Department of Physical Therapy University of Alabama at Birmingham Birmingham AL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"Barenius","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Clinical Science and Education Karolinska Institutet, S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Staci","family":"Thomas","sequence":"additional","affiliation":[{"name":"<!--<label>4<\/label>--> Division of Sports Medicine, Cincinnati Children\u2019s Hospital Medical Center and Department of Pediatrics University of Cincinnati College of Medicine 3333 Burnet Avenue MLC 10001 Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark V.","family":"Paterno","sequence":"additional","affiliation":[{"name":"<!--<label>4<\/label>--> Division of Sports Medicine, Cincinnati Children\u2019s Hospital Medical Center and Department of Pediatrics University of Cincinnati College of Medicine 3333 Burnet Avenue MLC 10001 Cincinnati OH USA"},{"name":"<!--<label>5<\/label>--> Division of Occupational Therapy and Physical Therapy, Division of Sports Medicine Cincinnati Children\u2019s Hospital Medical Center 3333 Burnet Avenue MLC 10001 Cincinnati OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura C.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"<!--<label>6<\/label>--> Sports Medicine Research Institute, Ohio State University Wexner Medical Center Columbus OH USA"},{"name":"<!--<label>7<\/label>--> Division of 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informed consent or parental permission\/assent (when younger than 18\u00a0years old) prior to participating in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}