{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:17:17Z","timestamp":1770743837439,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To assess the MRI\u2010measured structural integrity of hamstring autograft at 9\u00a0months after anterior cruciate ligament reconstruction (ACLR) surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A prospective cohort study was conducted including 34 patients (mean age 36.8\u2009\u00b1\u200911.8 years; 73.5% males) who underwent ACLR with hamstring autograft. In addition, 36 patients (mean age 39.2\u2009\u00b1\u200910.5 years; 69.4% males) without any ACL injury were also reviewed and served as control group. The primary outcome used for examining graft maturity at 9\u00a0months after ACLR was the MRI\u2010based signal\u2010to\u2010noise quotient (SNQ) of reconstructed ACL. SNQ values were stratified into 3 different categories: excellent:\u2009&lt;\u20090.1; good:\u2009\u2265\u20090.1 and\u2009\u2264\u20090.19; fair:\u2009\u2265\u20090.2. The KT\u20101000\u00a0knee arthrometer was used to measure the side\u2010to\u2010side difference in the anterior tibial translation between the ACLR knee and the contralateral healthy knee in the ACLR group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Reconstructed ACLs were found with a mean SNQ of 0.078\u2009\u00b1\u20090.061, while almost all ACL\u2010reconstructed patients (97%; 33 out of 34) were found with excellent or good SNQ values (&lt;\u20090.019). The mean KT\u20101000\u00a0in the ACLR group was 0.071\u00a0mm\u2009\u00b1\u20090.926\u00a0mm, while there were no patients in the ACLR cohort with a KT\u20101000 value\u2009&gt;\u20093\u00a0mm. The mean 9\u2010months MRI\u2010based SNQ of ACLR group was significantly higher compared to the mean MRI\u2010based SNQ of the control group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multiple regression analysis showed no correlation between SNQ and age, gender, time from injury to ACLR, graft size, or simultaneous treatment of additional intra\u2010articular knee lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this cohort of 34 ACL\u2010reconstructed patients, 97% of hamstring tendon autografts demonstrated excellent\/good MRI signal intensity and excellent functional results (KT\u20101000\u2009&lt;\u20093\u00a0mm) at 9\u00a0months after surgery. Based on this finding, it is suggested that return to sports after ACLR with hamstring autograft can be considered safe at 9\u00a0months post surgery. Furthermore, while structural integrity of the graft has been achieved at this time point, statistical differences found in SNQ values of ACL\u2010reconstructed patients compared to ACLs of healthy individuals highlight the continuing process of graft maturation and remodelling.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Level III.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-021-06830-2","type":"journal-article","created":{"date-parts":[[2022,1,17]],"date-time":"2022-01-17T19:03:57Z","timestamp":1642446237000},"page":"1893-1900","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Sufficient MRI graft structural integrity at 9\u00a0months after anterior cruciate ligament reconstruction with hamstring tendon autograft"],"prefix":"10.1002","volume":"30","author":[{"given":"Michael\u2010Alexander","family":"Malahias","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedics and Traumatology Clinical Ars Medica Via Grumo 16 6929 Gravesano Ticino Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7027-0415","authenticated-orcid":false,"given":"Francesco Maria","family":"Capece","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedics and Traumatology Clinical Ars Medica Via Grumo 16 6929 Gravesano Ticino Switzerland"},{"name":"<!--<label>5<\/label>--> University of Rome \u2018Tor Vergata\u2019 Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Ballarati","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Radiology Clinical Ars Medica Gravesano Ticino Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Vigan\u00f2","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> IRCCS Istituto Ortopedico Galeazzi Milano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Marano","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedics and Traumatology Clinical Ars Medica Via Grumo 16 6929 Gravesano Ticino Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Hofbauer","sequence":"additional","affiliation":[{"name":"<!--<label>4<\/label>--> Medical University of Vienna Wien Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danilo","family":"Togninalli","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedics and Traumatology Clinical Ars Medica Via Grumo 16 6929 Gravesano Ticino 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MV is a paid consultant of Lipogem SpA.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Institutional review board approval for the study was provided by the Medical University of Vienna (no. 1562\u20132014).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}