{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T02:21:07Z","timestamp":1793413267330,"version":"4.5.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T00:00:00Z","timestamp":1642982400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T00:00:00Z","timestamp":1642982400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T00:00:00Z","timestamp":1642982400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose of this study was to determine and compare the percentage of completely healed meniscal tears after arthroscopic repair combined with anterior cruciate ligament reconstruction (ACLR) for the different vascular zones of the meniscus.\n<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>PubMed, Embase, Web of Science, Cochrane library and Emcare were searched on 19\u00a0May 2020 for articles reporting healing rates after arthroscopic meniscal repair with concomitant ACLR for the different meniscal vascular zones as assessed by second\u2010look arthroscopy. Data on meniscal tears were extracted as located in zones 1, 2 or 3, according to the Cooper classification. Studies were graded in quality using a modified Newcastle\u2013Ottawa Scale. Pooled analyses were performed utilizing a random\u2010effects model. Meta\u2010analyses were performed using R version 3.6.2 and SPSS statistical software version 25.0. The study was registered with PROSPERO (ID:CRD42020176175).\n<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ten observational cohort studies met the inclusion criteria, accounting for 758\u00a0meniscal tear repairs in total. The pooled overall proportion of healing was 78% (95% CI 72\u201384%). The mean weighted proportion of healing was 83% (95% CI 76\u201390%) for studies (<jats:italic>n<\/jats:italic>\u2009=\u200910) reporting zone 1 tears and 69% (95% CI 59\u201379%) for studies (<jats:italic>n<\/jats:italic>\u2009=\u20099) reporting zone 2 tears. No study reported healing rates for zone 3 tears. The pooled overall odds ratio was 2.5 (95% CI 1.00\u22126.02), indicating zone 1 tears as 2.5 times more likely to heal than zone 2 tears.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrates that meniscal tears localized in vascular zone 1 were more likely to heal than those in zone 2.\n<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>IV.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-022-06862-2","type":"journal-article","created":{"date-parts":[[2022,1,24]],"date-time":"2022-01-24T03:02:56Z","timestamp":1642993376000},"page":"1976-1989","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Higher healing rate after meniscal repair with concomitant ACL reconstruction for tears located in vascular zone 1 compared to zone 2: a systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0588-7961","authenticated-orcid":false,"given":"L. M.","family":"Gerritsen","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery Leiden University Medical Center P.O. Box 9600 Post zone J10\u2010R83 2300 RC Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T. J. N.","family":"van der Lelij","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery Leiden University Medical Center P.O. Box 9600 Post zone J10\u2010R83 2300 RC Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"van Schie","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopedic Surgery Leiden University Medical Center P.O. Box 9600 Post zone J10\u2010R83 2300 RC Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Fiocco","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Mathematical Institute Leiden University Leiden The Netherlands"},{"name":"<!--<label>3<\/label>--> Department of Biomedical Data Science, Medical Statistics Section Leiden University Medical Center Leiden The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. R. A.","family":"van Arkel","sequence":"additional","affiliation":[{"name":"<!--<label>4<\/label>--> Department of Orthopedic Surgery Haaglanden Medical Center The Hague The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. G.","family":"Zuurmond","sequence":"additional","affiliation":[{"name":"<!--<label>5<\/label>--> Department of Orthopedic Surgery Isala Zwolle The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Keereweer","sequence":"additional","affiliation":[{"name":"<!--<label>6<\/label>--> Department of Otorhinolaryngology and Head and Neck Surgery Erasmus MC Cancer Institute, University Medical Center Rotterdam Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. B. A. A.","family":"van Driel","sequence":"additional","affiliation":[{"name":"<!--<label>5<\/label>--> Department of Orthopedic Surgery Isala Zwolle The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,24]]},"reference":[{"key":"e_1_2_13_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511400533"},{"key":"e_1_2_13_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354658201000205"},{"key":"e_1_2_13_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2013.10.003"},{"key":"e_1_2_13_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2017.04.016"},{"key":"e_1_2_13_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603516654945"},{"key":"e_1_2_13_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967119860806"},{"key":"e_1_2_13_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278\u20105919(20)30608\u20106"},{"key":"e_1_2_13_9_2","first-page":"10","article-title":"The meniscal healing process","volume":"2","author":"Albornoz PM","year":"2012","journal-title":"Muscles Ligaments Tendons J"},{"key":"e_1_2_13_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0197\u20102456(86)90046\u20102"},{"key":"e_1_2_13_11_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100038\u20101668123"},{"key":"e_1_2_13_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010019\u201005523\u20101"},{"key":"e_1_2_13_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516632504"},{"key":"e_1_2_13_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.1186"},{"key":"e_1_2_13_15_2","doi-asserted-by":"publisher","DOI":"10.5792\/ksrr.17.078"},{"key":"e_1_2_13_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00590\u2010018\u20102317\u20105"},{"key":"e_1_2_13_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00590\u2010014\u20101450\u2010z"},{"key":"e_1_2_13_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010020\u201005847\u20103"},{"key":"e_1_2_13_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.06.037"},{"key":"e_1_2_13_20_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546510388930"},{"key":"e_1_2_13_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/036354659101900614"},{"key":"e_1_2_13_22_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.K.01584"},{"key":"e_1_2_13_23_2","doi-asserted-by":"publisher","DOI":"10.1177\/03635465020300042001"},{"key":"e_1_2_13_24_2","doi-asserted-by":"publisher","DOI":"10.1053\/jars.2000.19434"},{"key":"e_1_2_13_25_2","first-page":"372","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"29","author":"Page MJ","year":"2021","journal-title":"BMJ"},{"key":"e_1_2_13_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2017.08.020"},{"key":"e_1_2_13_27_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546508316771"},{"key":"e_1_2_13_28_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00264\u2010013\u20102039\u20106"},{"key":"e_1_2_13_29_2","doi-asserted-by":"publisher","DOI":"10.1177\/2325967120905529"},{"key":"e_1_2_13_30_2","doi-asserted-by":"publisher","DOI":"10.1177\/23259671211033584"},{"key":"e_1_2_13_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603518783473"},{"key":"e_1_2_13_32_2","doi-asserted-by":"publisher","DOI":"10.1302\/2058\u20105241.3.170059"},{"key":"e_1_2_13_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2015.10.022"},{"key":"e_1_2_13_34_2","unstructured":"Wells GASB O'ConnelD PetersonJ WelchV LososM et al.The Newcastle\u2010Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta\u2010analyses. 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