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This study aimed to determine if the posterior tibial slope (PTS) and meniscal slope (MS) are associated with in vivo anterior\u2013posterior translation and internal tibia rotation during running and double\u2010leg drop jumps in healthy knees.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Nineteen collegiate athletes performed fast running at 5.0\u00a0m\/s on an instrumented treadmill and double\u2010leg drop jump from a 60\u00a0cm platform while biplane radiographs of the knee were acquired at 150\u00a0Hz. Tibiofemoral kinematics were determined using a validated model\u2010based tracking process. Medial and lateral PTS and MS were measured using magnetic resonance imaging (MRI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In fast running, more internal tibia rotation was associated with greater PTS (<jats:italic>\u03c1<\/jats:italic>\u2009=\u20090.336, <jats:italic>P<\/jats:italic>\u2009=\u20090.039) and MS (<jats:italic>\u03c1<\/jats:italic>\u2009=\u20090.405, <jats:italic>P<\/jats:italic>\u2009=\u20090.012) in the medial knee compartment. In the double\u2010leg drop jump, more internal tibia rotation was associated with greater PTS (<jats:italic>\u03c1<\/jats:italic>\u2009=\u20090.431, <jats:italic>P<\/jats:italic>\u2009=\u20090.007) and MS (<jats:italic>\u03c1<\/jats:italic>\u2009=\u20090.323, <jats:italic>P<\/jats:italic>\u2009=\u20090.005) in the medial knee compartment, as well as a greater PTS in the lateral knee compartment (<jats:italic>\u03c1<\/jats:italic>\u2009=\u20090.445, <jats:italic>P<\/jats:italic>\u2009=\u20090.005).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These findings suggest that the medial and lateral PTS and medial MS are associated with the amount of knee rotation during high\u2010impact activities. These in vivo findings improve our understanding of ACL injury risk by linking bone and meniscus morphology to dynamic kinematics.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-022-07163-4","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T12:18:41Z","timestamp":1663417121000},"page":"2366-2373","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Posterior tibial slope and meniscal slope correlate with in vivo tibial internal rotation during running and drop jump"],"prefix":"10.1002","volume":"31","author":[{"given":"Toshikazu","family":"Tanaka","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> UPMC Freddie Fu Sports Medicine Center, Department of Orthopaedic Surgery University of Pittsburgh Pittsburgh PA USA"},{"name":"<!--<label>2<\/label>--> Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo 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