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Patient demographics, patellofemoral articular cartilage status at surgery, and patient anatomical measures from imaging were obtained via chart review. Patients were contacted and outcomes assessed through collection of Norwich Patellar Instability (NPI) score, Knee injury and Osteoarthritis Outcome Score (KOOS), and Marx activity score as well as an assessment for recurrent patellar dislocation. Outcomes of patients with grade 0\u2013II patellofemoral cartilage damage were compared to those of patients with grade III\u2013IV cartilage damage.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred twenty\u2010two patients (76%) with a minimum of one year follow\u2010up were contacted at a mean of 4.8 years post\u2010operatively. A total of 63 patients (52%) had grade III or IV patellofemoral chondral damage at the time of surgery. The majority of the defects was on the medial patella (46 patients\u201072%) and the mean patellar defect size was 2.8\u00a0cm<jats:sup>2<\/jats:sup>. Among 93 patients who completed patient\u2010reported outcome scores, the 52 with grade III or IV chondral damage reported a significantly poorer KOOS Quality of Life than the 44 patients with grade 0 to II chondral damage (<jats:italic>p\u2009<\/jats:italic>=\u20090.041), controlling for patient age, sex, BMI, and anatomical factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with grade III or IV articular cartilage damage of the patellofemoral joint at the time of MPFL reconstruction demonstrated poorer KOOS knee\u2010related quality of life than patients without grade III or IV articular cartilage damage at a mean of 4.8 years following isolated MPFL reconstruction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>Level II<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-022-07221-x","type":"journal-article","created":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T11:03:51Z","timestamp":1668596631000},"page":"2794-2801","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Patellofemoral articular cartilage damage is associated with poorer patient\u2010reported outcomes following isolated medial patellofemoral ligament reconstruction"],"prefix":"10.1002","volume":"31","author":[{"given":"Roberto C.","family":"Gonzalez","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> The Ohio State University College of Medicine Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Ryskamp","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> The Ohio State University College of Medicine Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Swinehart","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parker A.","family":"Cavendish","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Milliron","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex C.","family":"DiBartola","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Duerr","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Flanigan","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Magnussen","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopaedics The Ohio State University, Jameson Crane Institute of Sports Medicine, Sports Medicine Research Institute 2835 Fred Taylor Drive 43202 Columbus OH 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