{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:22:50Z","timestamp":1760919770313,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T00:00:00Z","timestamp":1670544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20210843"],"award-info":[{"award-number":["BK20210843"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Affiliated Hospital of Nantong University","award":["No. Tdb2007"],"award-info":[{"award-number":["No. Tdb2007"]}]},{"name":"Natural Science Foundation for the youth of Jiangsu Province","award":["No. BK20210843"],"award-info":[{"award-number":["No. BK20210843"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the absorbable and nonabsorbable suture knots on the tendon on bone\u2010to\u2010tendon healing during the early phase in a rat rotator cuff tear (RCT) model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifty\u2010two male Sprague\u2013Dawley rats (10 weeks old; mean weight, 380 g) were used in this study, and 51 of them were randomly assigned into three groups: absorbable suture group (ASG, <jats:italic>n<\/jats:italic>\u2009=\u200922), nonabsorbable suture group (NSG, <jats:italic>n<\/jats:italic>\u2009=\u200922), and sham surgery group (SSG, <jats:italic>n<\/jats:italic>\u2009=\u20097), and the remaining rat was used to take surgical pictures. Bilateral supraspinatus tendon tears were created and repaired immediately in ASG and NSG. Three rats from ASG and NSG were killed for Western blot and histological evaluation at 3\u00a0days, 1 week, and 4 weeks after surgery. At 4 weeks, four rats from each group were killed for biomechanical test, and three rats from SSG were used for histological evaluation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Absorbable suture knots on the tendon completely degraded at 4 weeks. However, nonabsorbable suture knots remained intact between the tendon and articular side. ASG showed a stronger inflammatory reaction at 3\u00a0days and 1 week, but a weaker reaction at 4 weeks as confirmed by gross observation and Western blot. Besides, ASG showed superior biomechanical properties in terms of maximum load to failure and stiffness at 4 weeks. Modified Bonar score revealed superior maturity for tissue healing in ASG to that in NSG at 4 weeks. Furthermore, inferior bone\u2010to\u2010tendon interface and weakest link formation were observed in NSG on histologic images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Absorbable suture knots on the tendon contributed to better mechanical properties compared with the nonabsorbable one after rotator cuff repair.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-022-07269-9","type":"journal-article","created":{"date-parts":[[2022,12,9]],"date-time":"2022-12-09T05:03:34Z","timestamp":1670562214000},"page":"2572-2580","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Absorbable suture knots on the supraspinatus tendon prevent adverse effects of nonabsorbable suture knots in a rat model"],"prefix":"10.1002","volume":"31","author":[{"given":"Hui","family":"Ben","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Hand Surgery, College of Medicine Affiliated Hospital of Nantong University, University of Nantong 226001 Nantong Jiangsu China"},{"name":"<!--<label>2<\/label>--> Department of Orthopedic Surgery, ASAN Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunbing","family":"Luo","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Hand Surgery, College of Medicine Affiliated Hospital of Nantong University, University of Nantong 226001 Nantong Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Cheng","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Spine Surgery, College of Medicine Affiliated Hospital of Nantong University, University of Nantong Nantong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chu Hui","family":"Zeng","sequence":"additional","affiliation":[{"name":"<!--<label>4<\/label>--> Department of Radiology and Research Institute of Radiology, ASAN Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youlang","family":"Zhou","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Hand Surgery, College of Medicine Affiliated Hospital of Nantong University, University of Nantong 226001 Nantong Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u2010Ho","family":"Jeon","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopedic Surgery, ASAN Medical Center University of Ulsan College of Medicine Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5899-2792","authenticated-orcid":false,"given":"Yucheng","family":"Sun","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Hand Surgery, College of Medicine 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