{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T10:24:53Z","timestamp":1776335093520,"version":"3.51.2"},"reference-count":28,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T00:00:00Z","timestamp":1671494400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The purpose of the study was to evaluate the effect of skeletal age and lesion size, location, and grade on the success of nonoperative treatment for juvenile osteochondritis dissecans (OCD). It is hypothesized that skeletal maturity, including a combination of maturation phenotypes, correlates with nonoperative lesion healing.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The clinical and radiographic data on 52 patients aged 7\u201320 years treated for OCD of the distal femur between 2010 and 2019 were retrospectively reviewed. Knee radiographs were assessed for number of lesions present and lesion location, size, and stage. Assessments of skeletal maturation were performed on all antero\u2010posterior knee radiographs using the Roche, Wainer, and Thissen (RWT) method. Patients were categorized as healed if they demonstrated no pain on clinical examination. The relationship between skeletal maturity and nonoperative lesion healing was determined using Spearman rank correlations on available variables.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Neither chronological nor skeletal age was associated with surgical status (Rho\u2009=\u20090.03, n.s., and Rho\u2009=\u20090.13, n.s., respectively) or the healing status of nonoperatively treated OCD lesions (Rho\u2009=\u20090.44, n.s., and Rho\u2009=\u20090.03, n.s., respectively). Epiphyseal fusion status of the distal femoral physis was moderately correlated with nonoperative healing, but was not statistically significant (lateral femoral physis: Rho\u2009=\u20090.43, <jats:italic>p<\/jats:italic>\u2009=\u20090.05; medial femoral physis: Rho\u2009=\u20090.43, n.s.). Lesion length correlated with surgical status (Rho\u2009=\u2009\u2212 0.38, <jats:italic>p<\/jats:italic>\u2009=\u20090.009).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The extent of fusion of the distal femoral physis (multi\u2010stage grading) may be more strongly correlated with nonoperative healing than other markers of skeletal maturity or chronological age. Clinicians can use this as an additional radiographic sign when considering nonoperative treatment for juvenile OCD lesions in the distal femur. OCD lesion length and physeal fusion status appear to be more important for healing than patient age.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-022-07284-w","type":"journal-article","created":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T07:03:39Z","timestamp":1671519819000},"page":"2936-2943","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Physeal fusion status and lesion size are more important than patient age for healing of juvenile osteochodritis dessicans lesions of the distal femur"],"prefix":"10.1002","volume":"31","author":[{"given":"Olubusola","family":"Brimmo","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery University of Missouri, Missouri Orthopaedic Institute 1100 Virginia Ave 65201 Columbia MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie E.","family":"Boeyer","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery University of Missouri, Missouri Orthopaedic Institute 1100 Virginia Ave 65201 Columbia MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel G.","family":"Hoernschemeyer","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery University of Missouri, Missouri Orthopaedic Institute 1100 Virginia Ave 65201 Columbia MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Gray","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery University of Missouri, Missouri Orthopaedic Institute 1100 Virginia Ave 65201 Columbia MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5666-3354","authenticated-orcid":false,"given":"Dana L.","family":"Duren","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery University of Missouri, Missouri Orthopaedic Institute 1100 Virginia Ave 65201 Columbia MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2978-4801","authenticated-orcid":false,"given":"Sumit K.","family":"Gupta","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Department of Orthopaedic Surgery University of Missouri, Missouri Orthopaedic Institute 1100 Virginia Ave 65201 Columbia MO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,12,20]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/1947603517715736"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2019.08.050"},{"key":"e_1_2_11_4_2","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.20.01399"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1302\/2058\u20105241.4.180079"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.csm.2022.06.001"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11999\u2010012\u20102290\u2010y"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546506290127"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010013\u20102531\u2010y"},{"key":"e_1_2_11_10_2","volume-title":"Knee osteochondritis dissecans","author":"Mohr 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March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Hoernschemeyer is a paid presenter or speaker and receives research support from Biomarin and IP royalties, is a paid consultant and has stock or stock options from Orthopediatrics. Dr. Gupta is a board or committee member for the AAOS and a board or committee member for the Pediatric Orthopaedic Society of North America.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was approved by the Institutional review board of the University of Missouri (IRB#2,014,076).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}