{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T16:37:56Z","timestamp":1790440676067,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,5,12]],"date-time":"2023-05-12T00:00:00Z","timestamp":1683849600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/100008958","name":"Lawson Health Research Institute","doi-asserted-by":"publisher","award":["#F06-19"],"award-info":[{"award-number":["#F06-19"]}],"id":[{"id":"10.13039\/100008958","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008958","name":"Lawson Health Research Institute","doi-asserted-by":"publisher","award":["#F06\u201019"],"award-info":[{"award-number":["#F06\u201019"]}],"id":[{"id":"10.13039\/100008958","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To determine whether different regimens of multimodal analgesia will reduce postoperative pain scores, opioid consumption, costs and hospital length\u2010of\u2010stay following hip arthroscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From 2018 to 2021, 132 patients undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS) were included in this prospective, single\u2010center randomized controlled trial. Patients were randomized into four treatment groups:<jats:list>\n<jats:list-item><jats:p>Group 1\u2014Control: opioid medication (oxycodone\u2010acetaminophen 5\u00a0mg\/325\u00a0mg, 1\u20132 tabs q6H as needed), Heterotopic ossification prophylaxis\u2014Naprosyn 500\u00a0mg twice daily\u2009\u00d7\u20093 weeks);<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Group 2\u2014Control\u2009+\u2009postoperative sleeping aid (Zopiclone 7.5\u00a0mg nightly\u2009\u00d7\u20097\u00a0days);<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Group 3\u2014Control\u2009+\u2009preoperative and postoperative Gabapentin (600\u00a0mg orally, 1 h preoperatively; 600\u00a0mg postoperatively, 8 h following pre\u2010op dose);<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Group 4\u2014Control\u2009+\u2009pre\u2010medicate with Celecoxib (400\u00a0mg orally, 1 h preoperatively)<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p><jats:p>The primary outcome was pain measured with a visual analog scale, monitored daily for the first week and every other day for 6 weeks. Secondary outcomes included opioid consumption, healthcare resource use, and hospital length of stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patient characteristics were similar between groups. There were no statistically significant differences in pain scores between groups at any timepoint after adjusting for intra\u2010operative traction time, intra\u2010operative opioid administration and preoperative pain scores (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05). There were also no significant differences in the number of days that opioids were taken (n.s.) and the average daily morphine milligram equivalents consumed (n.s.). Similarly, there were no statistically significant differences in length of stay in the experimental groups, compared with the control group (n.s.). Finally, there were no differences in cost between groups (n.s.).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The routine use of Zopiclone, Celecoxib and Gabapentin did not improve postoperative pain control or reduce length\u2010of\u2010stay following hip arthroscopy. Therefore, these medications are not recommended for routine postoperative pain control following hip arthroscopy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>l.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-023-07445-5","type":"journal-article","created":{"date-parts":[[2023,5,11]],"date-time":"2023-05-11T22:01:58Z","timestamp":1683842518000},"page":"4016-4026","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Multimodal analgesia did not improve post\u2010operative pain scores, reduce opioid consumption or reduce length of stay following hip arthroscopy"],"prefix":"10.1002","volume":"31","author":[{"given":"Ryan M.","family":"Degen","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"},{"name":"<!--<label>2<\/label>--> Bone and Joint Institute Western University London ON Canada"},{"name":"<!--<label>3<\/label>--> Department of Surgery, Schulich School of Medicine and Dentistry Western University London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Firth","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herman","family":"Sehmbi","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"},{"name":"<!--<label>4<\/label>--> Department of Anesthesia, Schulich School of Medicine and Dentistry Western University London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Martindale","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Wanlin","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Chen","sequence":"additional","affiliation":[{"name":"<!--<label>5<\/label>--> Faculty of Health Sciences Western University London Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline D.","family":"Marsh","sequence":"additional","affiliation":[{"name":"<!--<label>5<\/label>--> Faculty of Health Sciences Western University London Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Willits","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"},{"name":"<!--<label>2<\/label>--> Bone and Joint Institute Western University London ON Canada"},{"name":"<!--<label>3<\/label>--> Department of Surgery, Schulich School of Medicine and Dentistry Western University London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne","family":"Bryant","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Fowler Kennedy Sport Medicine Clinic Western University 1151 Richmond Street, 3M Centre London ON Canada"},{"name":"<!--<label>2<\/label>--> Bone and Joint Institute Western University London ON Canada"},{"name":"<!--<label>3<\/label>--> Department of Surgery, Schulich School of Medicine and Dentistry Western University London ON Canada"},{"name":"<!--<label>5<\/label>--> Faculty of Health Sciences Western University London Canada"},{"name":"<!--<label>6<\/label>--> Department of Health Research Methods, Evidence and Impact McMaster University Hamilton Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,12]]},"reference":[{"key":"e_1_2_9_2_2","doi-asserted-by":"crossref","unstructured":"AbebeMM ArefayneNR TemesgenMM AdmassBAEvidence\u2010based perioperative pain management protocol for day case surgery in a resource limited setting: systematic review.Ann Med Surg(2022)10.1016\/j.amsu.2022.104322","DOI":"10.1016\/j.amsu.2022.104322"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOSGlobal\u2010D\u201021\u201000080"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.5435\/JAAOS\u2010D\u201021\u201000390"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocpiqo.2020.08.006"},{"key":"e_1_2_9_6_2","doi-asserted-by":"crossref","unstructured":"CunninghamDJ KwonNF AllenNB HanselmanAM AdamsSBTime and state legislation have decreased opioid prescribing in elective foot and ankle surgery in the United States.Foot Ankle Spec(2021)10.1177\/1938640021104336134872365","DOI":"10.1177\/2473011421S00162"},{"key":"e_1_2_9_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513510392"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2006.03.012"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2016.10.010"},{"key":"e_1_2_9_10_2","doi-asserted-by":"crossref","unstructured":"HuangY\u2010M WangC\u2010M WangC\u2010T LinW\u2010P HorngL\u2010C JiangC\u2010CPerioperative celecoxib administration for pain management after total knee arthroplasty\u2014a randomized controlled study.BMC Musculoskelet Disord(2008)10.1186\/1471\u20102474\u20109\u20107718986532","DOI":"10.1186\/1471-2474-9-77"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2022.05.029"},{"key":"e_1_2_9_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2017.01.016"},{"key":"e_1_2_9_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2015.12.022"},{"key":"e_1_2_9_14_2","doi-asserted-by":"publisher","DOI":"10.2174\/1872213X11307020004"},{"key":"e_1_2_9_15_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7006a4"},{"key":"e_1_2_9_16_2","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000152010.74739.B8"},{"key":"e_1_2_9_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.16844"},{"key":"e_1_2_9_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2012.11.013"},{"key":"e_1_2_9_19_2","doi-asserted-by":"crossref","unstructured":"O\u2019HaganET H\u00fcbscherM MillerCB GordonCJ GustinS BriggsN McAuleyJHZolpidem reduces pain intensity postoperatively: a systematic review and meta\u2010analysis of the effect of hypnotic medicines on post\u2010operative pain intensity.Syst Rev(2020)10.1186\/s13643\u2010020\u201001458\u2010832883342","DOI":"10.1186\/s13643-020-01458-8"},{"key":"e_1_2_9_20_2","doi-asserted-by":"crossref","unstructured":"OlsenMF BjerreE HansenMD HildenJ LandlerNE TendalB Hr\u00f3bjartssonAPain relief that matters to patients: systematic review of empirical studies assessing the minimum clinically important difference in acute pain.BMC Med(2017)10.1186\/s12916\u2010016\u20100775\u2010329145892","DOI":"10.1186\/s12916-016-0775-3"},{"key":"e_1_2_9_21_2","doi-asserted-by":"crossref","unstructured":"PasqualiniI Rull\u00e1nPJ DerenM KrebsVE MolloyRM NystromLM PiuzziNSTeam approach: use of opioids in orthopaedic practice.JBJS Rev(2023)10.2106\/JBJS.RVW.22.0020937549241","DOI":"10.2106\/JBJS.RVW.22.00209"},{"key":"e_1_2_9_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.asmr.2021.09.011"},{"key":"e_1_2_9_23_2","doi-asserted-by":"crossref","unstructured":"PengC LiC QuJ WuDGabapentin can decrease acute pain and morphine consumption in spinal surgery patients.Medicine (Baltimore)(2017)10.1097\/MD.000000000000646329390487","DOI":"10.1097\/MD.0000000000006463"},{"key":"e_1_2_9_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2021.07.013"},{"key":"e_1_2_9_25_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.0003\u20102409.2001.02399.x"},{"key":"e_1_2_9_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2021.02.029"},{"key":"e_1_2_9_27_2","unstructured":"Federal provincial and territorial Special Advisory Committee on the epidemic of opioid overdoses. Opioid\u2010 and stimulant\u2010related harms in Canada. Public Health Agency of Canada Ottawa 2023.https:\/\/health\u2010infobase.canada.ca\/substance\u2010related\u2010harms\/opioids\u2010stimulants\/"},{"key":"e_1_2_9_28_2","doi-asserted-by":"publisher","DOI":"10.1177\/03635465211036116"},{"key":"e_1_2_9_29_2","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100030\u20101248088"},{"key":"e_1_2_9_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00167\u2010010\u20101368\u2010x"},{"key":"e_1_2_9_31_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2004.022905"},{"key":"e_1_2_9_32_2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515602468"},{"key":"e_1_2_9_33_2","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e318265bacd"},{"key":"e_1_2_9_34_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2018.02.023"},{"key":"e_1_2_9_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00590\u2010013\u20101359\u2010y"}],"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-023-07445-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00167-023-07445-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00167-023-07445-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s00167-023-07445-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T08:53:28Z","timestamp":1760864008000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/s00167-023-07445-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,12]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1007\/s00167-023-07445-5"],"URL":"https:\/\/doi.org\/10.1007\/s00167-023-07445-5","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,12]]},"assertion":[{"value":"20 February 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study was registered with  (NCT03351439) and approved by our institutional review board (Western University Health Sciences REB ID# 110350).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}