{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:29:25Z","timestamp":1788154165040,"version":"build-2803163510"},"reference-count":37,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T00:00:00Z","timestamp":1688342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T00:00:00Z","timestamp":1688342400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T00:00:00Z","timestamp":1688342400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004047","name":"Karolinska Institute","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004047","name":"Karolinska Institutet","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004047","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>The primary aim of this study is to analyse the patient\u2010reported outcomes after ACLR complicated by septic arthritis. The secondary aim is to examine the 5\u2010year risk of revision surgery after primary ACLR complicated by septic arthritis. The hypothesis was that patients with septic arthritis after ACLR are more likely to have lower PROMs scores and an increased risk of revision, compared with patients without septic arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and methods<\/jats:title><jats:p>All primary ACLRs, with a hamstring or patellar tendon autograft (<jats:italic>n<\/jats:italic>\u2009=\u200923,075), in the Swedish Knee Ligament Register (SKLR) between 2006 and 2013 were linked with data from the Swedish National Board of Health and Welfare to identify patients with postoperative septic arthritis. These patients were verified in a nationwide medical records analysis and compared with patients without infection in the SKLR. The patient\u2010reported outcome was measured using the Knee injury and Osteoarthritis Index Score (KOOS) and the European Quality of Life Five Dimensions Index (EQ\u20105D) at 1, 2 and 5 years postoperatively and the 5\u2010year risk of revision surgery was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 268 events of septic arthritis (1.2%). The mean scores on the KOOS and EQ\u20105D index were significantly lower for patients with septic arthritis on all subscales on all follow\u2010up occasions compared with patients without septic arthritis. Patients with septic arthritis had a revision rate of 8.2% compared with 4.2% in patients without septic arthritis (adjusted hazard ratio 2.04; confidence interval 1.34\u20133.12).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients suffering from septic arthritis following ACLR are associated with poorer patient\u2010reported outcomes at 1\u2010, 2\u2010 and 5\u2010year follow\u2010ups compared with patients without septic arthritis. The risk of revision ACL reconstruction within 5 years of the primary operation for patients with septic arthritis following ACLR is almost twice as high, compared with patients without septic arthritis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Level of evidence<\/jats:title><jats:p>III.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s00167-023-07498-6","type":"journal-article","created":{"date-parts":[[2023,7,3]],"date-time":"2023-07-03T06:02:37Z","timestamp":1688364157000},"page":"4090-4098","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Poorer patient\u2010reported outcome and increased risk of revision at a 5\u2010year follow\u2010up among patients with septic arthritis following anterior cruciate ligament reconstruction: a register\u2010based cohort study of 23,075 primary anterior cruciate ligament reconstructions"],"prefix":"10.1002","volume":"31","author":[{"given":"Jesper Kraus","family":"Schmitz","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Stockholm Sports Trauma Research Center, Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3383-1586","authenticated-orcid":false,"given":"Osama","family":"Omar","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Clinical Science and Education, S\u00f6dersjukhuset Karolinska Institutet Vo Ortopedi, S\u00f6dersjukhuset, Sjukhusbacken 10 11883 Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Nordkvist","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Stockholm Sports Trauma Research Center, Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrik","family":"Hedevik","sequence":"additional","affiliation":[{"name":"<!--<label>3<\/label>--> Department of Health, Medicine and Caring Sciences Link\u00f6ping University Link\u00f6ping Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Per\u2010Mats","family":"Janarv","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Stockholm Sports Trauma Research Center, Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anders","family":"St\u00e5lman","sequence":"additional","affiliation":[{"name":"<!--<label>1<\/label>--> Stockholm Sports Trauma Research Center, Department of Molecular Medicine and Surgery Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,3]]},"reference":[{"key":"e_1_2_10_2_2","unstructured":"The Swedish Knee Ligament Registry Annual Report 2019.https:\/\/aclregister.nu\/documents\/. 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