{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T03:53:49Z","timestamp":1773287629657,"version":"3.50.1"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T00:00:00Z","timestamp":1392336000000},"content-version":"vor","delay-in-days":4488,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Knee surg. sports traumatol. arthrosc."],"published-print":{"date-parts":[[2001,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Autologous chondrocyte transplantation (ACT) for the treatment of cartilage injuries has been in clinical use for several years. Since this new technique is potentially more costly and invasive than traditional conservative therapies, we evaluated the effect of ACT on clinical outcome, absenteeism, disability status, and total direct economic burden in 57 patients with full\u2010thickness chondral lesions of the knee treated between 1987 and 1996. Patients graded good or excellent following ACT in the treatments groups were: femoral condyles (28\/33), femoral condyles with anterior cruciate ligament (ACL) repair (5\/5), osteochondritis dissecans (7\/8), and patellar lesions (9\/11). Pre\u2010ACT, 57\/57 patients were disabled and post\u2010ACT (mean follow\u2010up 7.3years) 44\/57 had no sickness, 10\/57 had minor disability, and 1\/57 was disabled. Two of the 57 patients suffered re\u2010injury during the follow\u2010up time. In the 10\u2010year period prior to ACT, the average cost of absenteeism and surgery was SEK 982,457 ($ 122,807) and SEK 47,000 ($ 5,875), respectively, compared to the post\u2010ACT period where both absenteeism and medical costs were dramatically reduced: SEK 9,508 ($ 1,189) and SEK 7,050 ($ 881), respectively. In conclusion, 49 of the 57 patients improved clinically as a result of the ACT treatment. A dramatic cost\u2010saving effect was demonstrated over a projected 10\u2010year period due to reduced absenteeism and disability.<\/jats:p>","DOI":"10.1007\/s001670100209","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T09:44:04Z","timestamp":1033897444000},"page":"358-363","source":"Crossref","is-referenced-by-count":66,"title":["Health economics benefits following autologous chondrocyte transplantation for patients with focal chondral lesions of the knee"],"prefix":"10.1002","volume":"9","author":[{"given":"A.","family":"Lindahl","sequence":"first","affiliation":[{"name":"<!--<label>1<\/label>--> Institute of Laboratory Medicine Department of Clinical Chemistry and Transfusion Medicine SE\u00a041345 Sahlgrens University Hospital Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Brittberg","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopedic Surgery Gothenburg University Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Peterson","sequence":"additional","affiliation":[{"name":"<!--<label>2<\/label>--> Department of Orthopedic Surgery Gothenburg University Gothenburg Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,14]]},"container-title":["Knee Surgery, Sports Traumatology, Arthroscopy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s001670100209.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s001670100209\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1007\/s001670100209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:01:51Z","timestamp":1760882511000},"score":1,"resource":{"primary":{"URL":"https:\/\/esskajournals.onlinelibrary.wiley.com\/doi\/10.1007\/s001670100209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["10.1007\/s001670100209"],"URL":"https:\/\/doi.org\/10.1007\/s001670100209","archive":["Portico"],"relation":{},"ISSN":["0942-2056","1433-7347"],"issn-type":[{"value":"0942-2056","type":"print"},{"value":"1433-7347","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}