{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T18:09:19Z","timestamp":1791310159641,"version":"4.3.1"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2018,3,29]],"date-time":"2018-03-29T00:00:00Z","timestamp":1522281600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1007\/s00192-018-3637-z","type":"journal-article","created":{"date-parts":[[2018,4,3]],"date-time":"2018-04-03T23:23:48Z","timestamp":1522797828000},"page":"439-446","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Differential gene expression of extracellular-matrix-related proteins in the vaginal apical compartment of women with pelvic organ prolapse"],"prefix":"10.1007","volume":"30","author":[{"given":"Haijiao","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukimi","family":"Kira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Hamuro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aki","family":"Takase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Tachibana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayasu","family":"Koyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,3,29]]},"reference":[{"issue":"3","key":"3637_CR1","doi-asserted-by":"publisher","first-page":"615","DOI":"10.1097\/01.AOG.0000175832.13266.bb","volume":"106","author":"AM Weber","year":"2005","unstructured":"Weber AM, Richter HE. Pelvic organ prolapse. Obstet Gynecol. 2005;106(3):615\u201334. \n                    https:\/\/doi.org\/10.1097\/01.Aog.0000175832.13266.Bb\n                    \n                  .","journal-title":"Obstet Gynecol"},{"key":"3637_CR2","first-page":"57","volume":"151","author":"JO DeLancey","year":"1990","unstructured":"DeLancey JO. Functional anatomy of the female lower urinary tract and pelvic floor. CIBA Found Symp. 1990;151:57\u201369.","journal-title":"CIBA Found Symp"},{"issue":"2","key":"3637_CR3","doi-asserted-by":"publisher","first-page":"578","DOI":"10.2353\/ajpath.2007.060662","volume":"170","author":"PG Drewes","year":"2007","unstructured":"Drewes PG, Yanagisawa H, Starcher B, Hornstra I, Csiszar K, Marinis SI, et al. Pelvic organ prolapse in fibulin-5 knockout mice - pregnancy-induced changes in elastic fiber homeostasis in mouse vagina. Am J Pathol. 2007;170(2):578\u201389. \n                    https:\/\/doi.org\/10.2353\/ajpath.2007.060662\n                    \n                  .","journal-title":"Am J Pathol"},{"key":"3637_CR4","doi-asserted-by":"publisher","unstructured":"Chin K, Wieslander C, Shi H, Balgobin S, Montoya TI, Yanagisawa H, et al. Pelvic organ support in animals with partial loss of fibulin-5 in the vaginal wall. Plos One. 2016;11(4). \n                    https:\/\/doi.org\/10.1371\/journal.pone.0152793\n                    \n                  .","DOI":"10.1371\/journal.pone.0152793"},{"issue":"1","key":"3637_CR5","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/S0002-9378(96)70243-0","volume":"175","author":"RC Bump","year":"1996","unstructured":"Bump RC, Mattiasson A, Bo K, Brubaker LP, DeLancey JO, Klarskov P, et al. The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction. Am J Obstet Gynecol. 1996;175(1):10\u20137.","journal-title":"Am J Obstet Gynecol"},{"issue":"8","key":"3637_CR6","doi-asserted-by":"publisher","first-page":"995","DOI":"10.1007\/s00192-010-1131-3","volume":"21","author":"OA Ibeanu","year":"2010","unstructured":"Ibeanu OA, Chesson RR, Sandquist D, Perez J, Santiago K, Nolan TE. Hypertrophic cervical elongation: clinical and histological correlations. Int Urogynecol J. 2010;21(8):995\u20131000. \n                    https:\/\/doi.org\/10.1007\/s00192-010-1131-3\n                    \n                  .","journal-title":"Int Urogynecol J"},{"issue":"10","key":"3637_CR7","doi-asserted-by":"publisher","first-page":"1211","DOI":"10.1007\/s00192-011-1502-4","volume":"22","author":"MA Bortolini","year":"2011","unstructured":"Bortolini MA, Rizk DE. Genetics of pelvic organ prolapse: crossing the bridge between bench and bedside in urogynecologic research. Int Urogynecol J. 2011;22(10):1211\u20139. \n                    https:\/\/doi.org\/10.1007\/s00192-011-1502-4\n                    \n                  .","journal-title":"Int Urogynecol J"},{"issue":"5","key":"3637_CR8","doi-asserted-by":"publisher","first-page":"2048","DOI":"10.1172\/JCI45636","volume":"121","author":"M Budatha","year":"2011","unstructured":"Budatha M, Roshanravan S, Zheng Q, Weislander C, Chapman SL, Davis EC, et al. Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans. J Clin Invest. 2011;121(5):2048\u201359. \n                    https:\/\/doi.org\/10.1172\/JCI45636\n                    \n                  .","journal-title":"J Clin Invest"},{"issue":"12","key":"3637_CR9","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.1007\/s00192-013-2111-1","volume":"24","author":"L Landsheere De","year":"2013","unstructured":"De Landsheere L, Munaut C, Nusgens B, Maillard C, Rubod C, Nisolle M, et al. Histology of the vaginal wall in women with pelvic organ prolapse: a literature review. Int Urogynecol J. 2013;24(12):2011\u201320. \n                    https:\/\/doi.org\/10.1007\/s00192-013-2111-1\n                    \n                  .","journal-title":"Int Urogynecol J"},{"issue":"6","key":"3637_CR10","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1111\/j.1447-0756.2011.01814.x","volume":"38","author":"BH Zhao","year":"2012","unstructured":"Zhao BH, Zhou JH. Decreased expression of elastin, fibulin-5 and lysyl oxidase-like 1 in the uterosacral ligaments of postmenopausal women with pelvic organ prolapse. J Obstet Gynaecol Res. 2012;38(6):925\u201331. \n                    https:\/\/doi.org\/10.1111\/j.1447-0756.2011.01814.x\n                    \n                  .","journal-title":"J Obstet Gynaecol Res"},{"issue":"6","key":"3637_CR11","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1111\/jog.12952","volume":"42","author":"A Hamuro","year":"2016","unstructured":"Hamuro A, Tachibana D, Wang H, Hayashi M, Yanai S, Kurihara Y, et al. Combined reconstructive surgery involving uterosacral colpopexy and anterior vaginal mesh implantation for pelvic organ prolapse. J Obstet Gynaecol Res. 2016;42(6):707\u201315. \n                    https:\/\/doi.org\/10.1111\/jog.12952\n                    \n                  .","journal-title":"J Obstet Gynaecol Res"},{"issue":"3","key":"3637_CR12","doi-asserted-by":"publisher","first-page":"1083","DOI":"10.1128\/MCB.01330-06","volume":"27","author":"Q Zheng","year":"2007","unstructured":"Zheng Q, Davis EC, Richardson JA, Starcher BC, Li T, Gerard RD, et al. Molecular analysis of fibulin-5 function during de novo synthesis of elastic fibers. Mol Cell Biol. 2007;27(3):1083\u201395. \n                    https:\/\/doi.org\/10.1128\/MCB.01330-06\n                    \n                  .","journal-title":"Mol Cell Biol"},{"issue":"6868","key":"3637_CR13","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1038\/415168a","volume":"415","author":"H Yanagisawa","year":"2002","unstructured":"Yanagisawa H, Davis EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson JA, et al. Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature. 2002;415(6868):168\u201371. \n                    https:\/\/doi.org\/10.1038\/415168a\n                    \n                  .","journal-title":"Nature"},{"issue":"3\u20134","key":"3637_CR14","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1007\/s12079-009-0065-3","volume":"3","author":"H Yanagisawa","year":"2009","unstructured":"Yanagisawa H, Schluterman MK, Brekken RA. Fibulin-5, an integrin-binding matricellular protein: its function in development and disease. Journal Cell Commun Signal. 2009;3(3\u20134):337\u201347. \n                    https:\/\/doi.org\/10.1007\/s12079-009-0065-3\n                    \n                  .","journal-title":"Journal Cell Commun Signal"},{"issue":"11","key":"3637_CR15","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1007\/s00192-010-1199-9","volume":"21","author":"M Alarab","year":"2010","unstructured":"Alarab M, Bortolini MA, Drutz H, Lye S, Shynlova O. LOX family enzymes expression in vaginal tissue of premenopausal women with severe pelvic organ prolapse. Int Urogynecol J. 2010;21(11):1397\u2013404. \n                    https:\/\/doi.org\/10.1007\/s00192-010-1199-9\n                    \n                  .","journal-title":"Int Urogynecol J"},{"issue":"1","key":"3637_CR16","doi-asserted-by":"publisher","first-page":"23","DOI":"10.7555\/JBR.27.20110142","volume":"27","author":"Y Zhou","year":"2013","unstructured":"Zhou Y, Ling O, Bo L. Expression and significance of lysyl oxidase-like 1 and fibulin-5 in the cardinal ligament tissue of patients with pelvic floor dysfunction. Journal Biomed Res. 2013;27(1):23\u20138. \n                    https:\/\/doi.org\/10.7555\/JBR.27.20110142\n                    \n                  .","journal-title":"Journal Biomed Res"},{"issue":"4","key":"3637_CR17","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1007\/s00192-008-0737-1","volume":"20","author":"MH Kerkhof","year":"2009","unstructured":"Kerkhof MH, Hendriks L, Brolmann HA. Changes in connective tissue in patients with pelvic organ prolapse--a review of the current literature. Int Urogynecol J Pelvic Floor Dysfunct. 2009;20(4):461\u201374. \n                    https:\/\/doi.org\/10.1007\/s00192-008-0737-1\n                    \n                  .","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"7","key":"3637_CR18","first-page":"307","volume":"109","author":"SV Antovska","year":"2008","unstructured":"Antovska SV. A new modification of the POPQ system - its effectiveness in the diagnosis of supravaginal elongation of the uterine cervix in cases with genital prolapse. Bratisl Med J. 2008;109(7):307\u201312.","journal-title":"Bratisl Med J"},{"issue":"8","key":"3637_CR19","doi-asserted-by":"publisher","first-page":"1095","DOI":"10.1007\/s00192-012-1747-6","volume":"23","author":"MB Berger","year":"2012","unstructured":"Berger MB, Ramanah R, Guire KE, DeLancey JO. Is cervical elongation associated with pelvic organ prolapse? Int Urogynecol J. 2012;23(8):1095\u2013103. \n                    https:\/\/doi.org\/10.1007\/s00192-012-1747-6\n                    \n                  .","journal-title":"Int Urogynecol J"},{"issue":"7","key":"3637_CR20","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1083\/jcb.200611026","volume":"176","author":"M Hirai","year":"2007","unstructured":"Hirai M, Ohbayashi T, Horiguchi M, Okawa K, Hagiwara A, Chien KR, et al. Fibulin-5\/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo. J Cell Biol. 2007;176(7):1061\u201371. \n                    https:\/\/doi.org\/10.1083\/jcb.200611026\n                    \n                  .","journal-title":"J Cell Biol"},{"issue":"4","key":"3637_CR21","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1016\/j.matbio.2009.03.004","volume":"28","author":"J Choi","year":"2009","unstructured":"Choi J, Bergdahl A, Zheng Q, Starcher B, Yanagisawa H, Davis EC. Analysis of dermal elastic fibers in the absence of fibulin-5 reveals potential roles for fibulin-5 in elastic fiber assembly. Matrix Biol. 2009;28(4):211\u201320. \n                    https:\/\/doi.org\/10.1016\/j.matbio.2009.03.004\n                    \n                  .","journal-title":"Matrix Biol"},{"issue":"4","key":"3637_CR22","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.jogc.2016.10.012","volume":"39","author":"PA Nosti","year":"2017","unstructured":"Nosti PA, Gutman RE, Iglesia CB, Park AJ, Tefera E, Sokol AI. Defining cervical elongation: a prospective observational study. J Obstet Gynaecol Can. 2017;39(4):223\u20138. \n                    https:\/\/doi.org\/10.1016\/j.jogc.2016.10.012\n                    \n                  .","journal-title":"J Obstet Gynaecol Can"}],"container-title":["International Urogynecology Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00192-018-3637-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-018-3637-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-018-3637-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T17:18:08Z","timestamp":1566839888000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00192-018-3637-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,29]]},"references-count":22,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["3637"],"URL":"https:\/\/doi.org\/10.1007\/s00192-018-3637-z","relation":{},"ISSN":["0937-3462","1433-3023"],"issn-type":[{"value":"0937-3462","type":"print"},{"value":"1433-3023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,29]]},"assertion":[{"value":"27 December 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 March 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 March 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}