{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T04:11:35Z","timestamp":1792901495315,"version":"4.5.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005788","name":"Medical University of Vienna","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005788","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1007\/s00192-019-04070-0","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T09:02:44Z","timestamp":1565168564000},"page":"1577-1582","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["Effectiveness of hormones in postmenopausal pelvic floor dysfunction\u2014International Urogynecological Association research and development\u2014committee opinion"],"prefix":"10.1007","volume":"31","author":[{"given":"Barbara","family":"Bodner-Adler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"May","family":"Alarab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra M.","family":"Ruiz-Zapata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallavi","family":"Latthe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,8,7]]},"reference":[{"key":"4070_CR1","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1007\/s001920170012","volume":"12","author":"RG Rogers","year":"2011","unstructured":"Rogers RG, Villareal A, Kammerer-Doak D, Qualls C. Sexual function in women with and without urinary incontinence and\/or pelvic organ prolapse. Int Urogynecol J Pelvic Floor Dysfunct. 2011;12:361\u20135.","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"10","key":"4070_CR2","doi-asserted-by":"publisher","first-page":"3728","DOI":"10.1210\/jc.2014-1216","volume":"99","author":"DD Rahn","year":"2014","unstructured":"Rahn DD, Good MM, Roshanravan SM, Shi H, Schaffer JI, Singh RJ, et al. Effects of preoperative local estrogen in postmenopausal women with prolapse: a randomized trial. J Clin Endocrinol Metab. 2014;99(10):3728\u201336.","journal-title":"J Clin Endocrinol Metab"},{"key":"4070_CR3","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1016\/j.ajog.2004.10.602","volume":"192","author":"S Swift","year":"2015","unstructured":"Swift S, Woodman P, O\u2019Boyle A, et al. Pelvic organ support study (POSST): the distribution, clinical definition and epidemiologic condition of pelvic organ support defects. Am J Obstet Gynecol. 2015;192:795\u2013806.","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"4070_CR4","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1001\/jama.288.3.321","volume":"288","author":"JE Rossouw","year":"2002","unstructured":"Rossouw JE, Anderson GL, Prentice RL, et al. Writing Group for the Women\u2019s Health Initiative investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women\u2019s Health Initiative randomized controlled trial. JAMA. 2002;288(3):321\u201333.","journal-title":"JAMA"},{"issue":"7","key":"4070_CR5","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1001\/jama.280.7.605","volume":"280","author":"S Hulley","year":"1998","unstructured":"Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and estrogen\/progestin replacement study (HERS) research group. JAMA. 1998;280(7):605\u201313.","journal-title":"JAMA"},{"issue":"6","key":"4070_CR6","doi-asserted-by":"publisher","first-page":"704","DOI":"10.1016\/j.ajog.2016.07.045","volume":"215","author":"J Gandhi","year":"2016","unstructured":"Gandhi J, Chen A, Daqur G, Suh Y, Smith N, Cali B, et al. Genitourinary syndrome of menopause: an overview of clinical manifestations, pathophysiology, etiology, evaluation, and management. Am J Obstet Gynecol. 2016;215(6):704\u201311.","journal-title":"Am J Obstet Gynecol"},{"issue":"4 Suppl 1","key":"4070_CR7","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S0090-4295(03)00676-9","volume":"62","author":"D Robinson","year":"2003","unstructured":"Robinson D, Cardozo LD. The role of estrogens in female lower urinary tract dysfunction. Urology. 2003;62(4 Suppl 1):45\u201351.","journal-title":"Urology"},{"issue":"11","key":"4070_CR8","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1080\/00016340701625446","volume":"86","author":"MW S\u00f6derberg","year":"2007","unstructured":"S\u00f6derberg MW, Johansson B, Masironi B, Bystr\u00f6m B, Falconer C, Sahlin L, et al. Pelvic floor sex steroid hormone receptors, distribution and expression in pre- and postmenopausal stress urinary incontinent women. Acta Obstet Gynecol Scand. 2007;86(11):1377\u201384.","journal-title":"Acta Obstet Gynecol Scand"},{"key":"4070_CR9","doi-asserted-by":"crossref","first-page":"130","DOI":"10.18553\/jmcp.2014.20.2.130","volume":"20","author":"KS Coyne","year":"2014","unstructured":"Coyne KS, Wein A, Nicholson S, Kvasz M, Chen CI, Milsom I. Economic burden of urgency urinary incontinence in the United States: a systematic review. J Manag Care Pharm. 2014;20:130\u201340.","journal-title":"J Manag Care Pharm"},{"issue":"9","key":"4070_CR10","doi-asserted-by":"publisher","first-page":"e 0136265","DOI":"10.1371\/journal.pone.0136265","volume":"10","author":"MA Weber","year":"2015","unstructured":"Weber MA, Kleijn MH, Langendam M, Heineman MJ, Roovers JP. Local oestrogen for pelvic floor disorders. A systematic review. PLoS One. 2015;10(9):e 0136265.","journal-title":"PLoS One"},{"key":"4070_CR11","doi-asserted-by":"publisher","first-page":"892","DOI":"10.1111\/j.0001-6349.2004.00581.x","volume":"83","author":"L Cardozo","year":"2004","unstructured":"Cardozo L, Gunnar L, McClish D, Versi E, et al. A systematic review of the effects of estrogens for symptoms suggestive of overactive bladder. Acta Obstet Gynecol Scand. 2004;83:892\u20137.","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"2","key":"4070_CR12","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1002\/nau.22809","volume":"35","author":"AT Hanna-Mitchell","year":"2016","unstructured":"Hanna-Mitchell AT, Robinson D, Cardozo L, Everaert K, Petkov GV. Do we need to know more about the effects of hormones on lower urinary tract dysfunction? ICI-RS 2014. Neurourol Urodyn. 2016;35(2):299\u2013303.","journal-title":"Neurourol Urodyn"},{"key":"4070_CR13","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1016\/0028-2243(92)90059-8","volume":"44","author":"PS Eriksen","year":"1992","unstructured":"Eriksen PS, Rasmussen H. Low dose 17b-oestradiol vaginal tablets in the treatment of atrophic vaginitis: a double-blind placebo controlled study. Eur J Obstet Gynecol Reprod Biol. 1992;44:137\u201344.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"9","key":"4070_CR14","doi-asserted-by":"publisher","first-page":"962","DOI":"10.1097\/gme.0b013e3182104977","volume":"18","author":"RS Nelken","year":"2011","unstructured":"Nelken RS, Ozel BZ, Leegant AR, Felix JC, Mishell DR. Randomized trial of estradiol vaginal ring versus oral oxybutynin for the treatment of overactive bladder. Menopause. 2011;18(9):962\u20136.","journal-title":"Menopause"},{"issue":"1","key":"4070_CR15","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1002\/nau.20583","volume":"28","author":"LH Tseng","year":"2009","unstructured":"Tseng LH, Wang AC, Chang YL, Soong YK, Lloyd LK, Ko YJ. Randomized comparison of tolterodine with vaginal estrogen cream versus tolterodine alone for the treatment of postmenopausal women with overactive bladder syndrome. Neurorurol Urodyn. 2009;28(1):47\u201351.","journal-title":"Neurorurol Urodyn"},{"issue":"1","key":"4070_CR16","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00192-014-2554-z","volume":"26","author":"DD Rahn","year":"2015","unstructured":"Rahn DD, Ward RM, Sanses TV, Carberry C, Mamik MM, Meriwether KV, et al. Vaginal estrogen in postmenopausal women with pelvic floor disorers: systematic review and practice guidelines. Int Urogynecol J. 2015;26(1):3\u201313.","journal-title":"Int Urogynecol J"},{"issue":"4","key":"4070_CR17","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1097\/SPV.0000000000000256","volume":"22","author":"DR Ellington","year":"2016","unstructured":"Ellington DR, Szychowski JM, Malek JM, Gerten KA, Burgio KL, Richter HE. Combined Tolterodine and vaginal estradiol cream for overactive bladder symptoms after randomized single-therapy treatment. Female Pelvic Med Reconstr Surg. 2016;22(4):254\u201360.","journal-title":"Female Pelvic Med Reconstr Surg"},{"issue":"2","key":"4070_CR18","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1080\/09513590.2018.1500534","volume":"35","author":"MC Schiavi","year":"2019","unstructured":"Schiavi MC, D\u2019Oria O, Aleksa N, Vena F, Prata G, Di Tucci C, et al. Usefulness of ospemifene in the treatment of urgency in menopausal patients affected by mixed urinary incontinence underwent mid-urethral slings surgery. Gynecol Endocrinol. 2019;35(2):155\u20139.","journal-title":"Gynecol Endocrinol"},{"issue":"8","key":"4070_CR19","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1080\/09513590.2018.1441398","volume":"34","author":"MC Schiavi","year":"2018","unstructured":"Schiavi MC, Sciuga V, Giannini A, Vena F, D\u2019oria O, Prata G, et al. Overactive bladder syndrome treatment with ospemifene in menopausal patients with vulvovaginal atrophy: improvement of sexuality? Gynecol Endocrinol. 2018;34(8):666\u20139.","journal-title":"Gynecol Endocrinol"},{"issue":"4","key":"4070_CR20","doi-asserted-by":"publisher","first-page":"722","DOI":"10.1016\/S0029-7844(98)00175-6","volume":"92","author":"L Cardozo","year":"1998","unstructured":"Cardozo L, Bachmann G, McClish D, Fonda D, Birgerson L. Meta-analysis of estrogen therapy in the management of urogenital atrophy in postmenopausal women: second report of the hormones and urogenital therapy committee. Obstet Gynecol. 1998;92(4):722\u20137.","journal-title":"Obstet Gynecol"},{"key":"4070_CR21","doi-asserted-by":"publisher","unstructured":"Mitchell CM, Reed S, Diem S, Larson JC, Newton KM, Ensrud KE, et al. Efficacy of vaginal estradiol or vaginal moisturizer vs placebo for treating postmenopausal vulvovaginal symptoms a randomized clinical trial. JAMA Intern Med. 2018. https:\/\/doi.org\/10.1001\/jamainternmed.2018.0116 .","DOI":"10.1001\/jamainternmed.2018.0116"},{"issue":"6","key":"4070_CR22","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1016\/j.juro.2018.04.088","volume":"200","author":"L Smith","year":"2018","unstructured":"Smith L, Brown J, Wyman JF, Berry A, Newman DK, Stapleton AE. Treatment and prevention of recurrent lower urinary tract infections in women: a rapid review with practice recommendations. J Urol. 2018;200(6):1174\u201391.","journal-title":"J Urol"},{"key":"4070_CR23","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1097\/01.gco.0000242958.25244.ff","volume":"18","author":"M Alperin","year":"2006","unstructured":"Alperin M, Moalli PA. Remodeling of vaginal connective tissue in patients with prolapse. Curr Opin Obstet Gynecol. 2006;18:544\u201350.","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"1","key":"4070_CR24","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1097\/GME.0000000000001209","volume":"26","author":"M Alperin","year":"2019","unstructured":"Alperin M, Burnett L, Lukacz E, Brubaker L. The mysteries of menopause and urogynecologic health: clinical and scientific gaps. Menopause. 2019;26(1):103\u201311.","journal-title":"Menopause"},{"issue":"4","key":"4070_CR25","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1177\/2053369115614704","volume":"21","author":"S Bulchandani","year":"2015","unstructured":"Bulchandani S, Toozs-Hobson P, Verghese T, Latthe P. Does vaginal estrogen treatment with support pessaries in vaginal prolapse reduce complications? Post Reprod Health. 2015;21(4):141\u20135.","journal-title":"Post Reprod Health"},{"issue":"9","key":"4070_CR26","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1007\/s00192-016-3000-1","volume":"27","author":"SG Dessie","year":"2016","unstructured":"Dessie SG, Armstrong K, Modest AM, Hacker MR, Hota LS. Effect of vaginal estrogen on pessary use. Int Urogynecol J Pelvic Floor Dysfunct. 2016;27(9):1423\u20139.","journal-title":"Int Urogynecol J Pelvic Floor Dysfunct"},{"issue":"4","key":"4070_CR27","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1097\/SPV.0b013e31825e6401","volume":"18","author":"DR Karp","year":"2012","unstructured":"Karp DR, Jean-Michel M, Johnston Y, Suciu G, Aguilar VC, Davila GW. A randomized trial of the impact of local estrogen on postoperative tissue quality after vaginal reconstructive surgery. Female Pelvic Med Reconstr Surg. 2012;18(4):211\u20135.","journal-title":"Female Pelvic Med Reconstr Surg"},{"issue":"1","key":"4070_CR28","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1097\/SPV.0b013e318278cc40","volume":"19","author":"CM Vaccaro","year":"2013","unstructured":"Vaccaro CM, Fellner AN, Crisp CC, Estanol MV, Kleeman SD, et al. Histologic and cytologic effects of vaginal estrogen in women with pelvic organ prolapse. A randomized controlled trial. Female Pelvic Med Reconstr Surg. 2013;19(1):34\u20139.","journal-title":"Female Pelvic Med Reconstr Surg"},{"key":"4070_CR29","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1111\/j.1463-1318.2008.01624.x","volume":"11","author":"G Pinedo","year":"2009","unstructured":"Pinedo G, Garcia E, Zarate AJ, et al. Are topical oestrogens useful in fecal incontinence? Double blind randomized trial. Color Dis. 2009;11:390\u20133.","journal-title":"Color Dis"},{"key":"4070_CR30","first-page":"CD 001405","volume":"10","author":"JD Cody","year":"2012","unstructured":"Cody JD, Jacobs ML, Richardson K, Moehrer B, Hextall A. Estrogen therapy for urinary incontinence in post-menopausal women. Chochrane Database Syst Rev. 2012;10:CD 001405.","journal-title":"Chochrane Database Syst Rev"},{"key":"4070_CR31","first-page":"12","volume":"83","author":"JA Fantl","year":"1994","unstructured":"Fantl JA, Cardozo L, McClish DK. Estrogen therapy in the management of urinary incontinence in postmenopausal women: a meta-analysis. First report of the hormones and urogenital therapy committee. Obstet Gynecol. 1994;83:12\u20138.","journal-title":"Obstet Gynecol"},{"key":"4070_CR32","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1001\/jama.293.8.935","volume":"293","author":"SL Hendrix","year":"2005","unstructured":"Hendrix SL, Cochrane BB, Nygaard IE, Handa VL, Barnabei VM, Iglesia C, et al. Effects of estrogen with and without progestin on urinary incontinence. JAMA. 2005;293:935\u201348.","journal-title":"JAMA"},{"issue":"8","key":"4070_CR33","doi-asserted-by":"publisher","first-page":"1915","DOI":"10.1053\/j.gastro.2017.02.005","volume":"152","author":"K Staller","year":"2017","unstructured":"Staller K, Townsend MK, Khalili H, et al. Menopausal hormone therapy is associated with increased risk of fecal incontinence in women after menopause. Gastroenterology. 2017;152(8):1915\u20131921.e1.","journal-title":"Gastroenterology"},{"key":"4070_CR34","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007063","volume":"9","author":"SI Ismail","year":"2010","unstructured":"Ismail SI, Bain C, Hagen S. Oestrogens for treatment or prevention of pelvic organ prolapse in postmenopausal women. Cochrane Database Syst Rev. 2010;9:CD007063. https:\/\/doi.org\/10.1002\/14651858.CD007063 .","journal-title":"Cochrane Database Syst Rev"}],"container-title":["International Urogynecology Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-019-04070-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00192-019-04070-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-019-04070-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T05:41:22Z","timestamp":1610775682000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00192-019-04070-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8,7]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["4070"],"URL":"https:\/\/doi.org\/10.1007\/s00192-019-04070-0","relation":{},"ISSN":["0937-3462","1433-3023"],"issn-type":[{"value":"0937-3462","type":"print"},{"value":"1433-3023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,8,7]]},"assertion":[{"value":"11 May 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 July 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 August 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}