{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:55:50Z","timestamp":1780527350914,"version":"3.54.1"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100000070","name":"National Institute of Biomedical Imaging and Bioengineering","doi-asserted-by":"publisher","award":["5T32EB003392-13"],"award-info":[{"award-number":["5T32EB003392-13"]}],"id":[{"id":"10.13039\/100000070","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008497","name":"Boston Scientific Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008497","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD054214"],"award-info":[{"award-number":["U10 HD054214"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD041267"],"award-info":[{"award-number":["U10 HD041267"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD041261"],"award-info":[{"award-number":["U10 HD041261"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD069013"],"award-info":[{"award-number":["U10 HD069013"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD069025"],"award-info":[{"award-number":["U10 HD069025"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD069010"],"award-info":[{"award-number":["U10 HD069010"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD069006"],"award-info":[{"award-number":["U10 HD069006"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U10 HD054215"],"award-info":[{"award-number":["U10 HD054215"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","award":["U01 HD069031"],"award-info":[{"award-number":["U01 HD069031"]}],"id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s00192-020-04511-1","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T10:02:56Z","timestamp":1598954576000},"page":"809-818","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Methods for the defining mechanisms of anterior vaginal wall descent (DEMAND) study"],"prefix":"10.1007","volume":"32","author":[{"given":"Pamela A.","family":"Moalli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaniel T.","family":"Bowen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Abramowitch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E.","family":"Lockhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison C.","family":"Weidner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly E.","family":"Richter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles R.","family":"Rardin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko M.","family":"Komesu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi S.","family":"Harvie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beri M.","family":"Ridgeway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna","family":"Mazloomdoost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Shaffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie G.","family":"Gantz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the NICHD Pelvic Floor Disorders Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,1]]},"reference":[{"issue":"7","key":"4511_CR1","doi-asserted-by":"publisher","first-page":"971","DOI":"10.1111\/j.1471-0528.2005.00568.x","volume":"112","author":"GA Digesu","year":"2005","unstructured":"Digesu GA, Chaliha C, Salvatore S, Hutchings A, Khullar V. The relationship of vaginal prolapse severity to symptoms and quality of life. BJOG An Int J Obstet Gynaecol. 2005;112(7):971\u20136. https:\/\/doi.org\/10.1111\/j.1471-0528.2005.00568.x.","journal-title":"BJOG An Int J Obstet Gynaecol."},{"issue":"7","key":"4511_CR2","doi-asserted-by":"publisher","first-page":"1145","DOI":"10.1002\/nau.22205","volume":"31","author":"R Zielinski","year":"2012","unstructured":"Zielinski R, Miller J, Low LK, Sampselle C, Delancey JOL. The relationship between pelvic organ prolapse, genital body image, and sexual health. Neurourol Urodyn. 2012;31(7):1145\u20138. https:\/\/doi.org\/10.1002\/nau.22205.","journal-title":"Neurourol Urodyn"},{"issue":"5","key":"4511_CR3","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1097\/AOG.0b013e31816bbe85","volume":"111","author":"VL Handa","year":"2008","unstructured":"Handa VL, Cundiff G, Chang HH, Helzlsouer KJ. Female sexual function and pelvic floor disorders. Obstet Gynecol. 2008;111(5):1045\u201352. https:\/\/doi.org\/10.1097\/AOG.0b013e31816bbe85.","journal-title":"Obstet Gynecol"},{"issue":"6","key":"4511_CR4","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1097\/AOG.0000000000000286","volume":"123","author":"JM Wu","year":"2014","unstructured":"Wu JM, Matthews CA, Conover MM, Pate V, Jonsson Funk M. Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery. Obstet Gynecol. 2014;123(6):1201\u20136. https:\/\/doi.org\/10.1097\/AOG.0000000000000286.","journal-title":"Obstet Gynecol"},{"issue":"5","key":"4511_CR5","doi-asserted-by":"publisher","first-page":"981","DOI":"10.1097\/AOG.0b013e3182a8a5e4","volume":"122","author":"KS Eilber","year":"2013","unstructured":"Eilber KS, Alperin M, Khan A, et al. Outcomes of vaginal prolapse surgery among female medicare beneficiaries: the role of apical support. Obstet Gynecol. 2013;122(5):981\u20137. https:\/\/doi.org\/10.1097\/AOG.0b013e3182a8a5e4.","journal-title":"Obstet Gynecol"},{"key":"4511_CR6","doi-asserted-by":"publisher","unstructured":"Davila GW, Baessler K, Cosson M, Cardozo L. Selection of patients in whom vaginal graft use may be appropriate: Consensus of the 2nd IUGA grafts roundtable: Optimizing safety and appropriateness of graft use in transvaginal pelvic reconstructive surgery. Int Urogynecol J. 2012;23(SUPPL. 1). https:\/\/doi.org\/10.1007\/s00192-012-1677-3","DOI":"10.1007\/s00192-012-1677-3"},{"issue":"10","key":"4511_CR7","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1001\/jama.2014.1719","volume":"311","author":"MD Barber","year":"2014","unstructured":"Barber MD, Brubaker L, Burgio KL, et al. Comparison of 2 transvaginal surgical approaches and perioperative behavioral therapy for apical vaginal prolapse: the OPTIMAL randomized trial. JAMA - J Am Med Assoc. 2014;311(10):1023\u201334. https:\/\/doi.org\/10.1001\/jama.2014.1719.","journal-title":"JAMA - J Am Med Assoc."},{"issue":"15","key":"4511_CR8","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.1001\/jama.2018.2827","volume":"319","author":"JE Jelovsek","year":"2018","unstructured":"Jelovsek JE, Barber MD, Norton P, et al. Effect of uterosacral ligament suspension vs sacrospinous ligament fixation with or without perioperative behavioral therapy for pelvic organ vaginal prolapse on surgical outcomes and prolapse symptoms at 5 years in the OPTIMAL randomized clinical trial. JAMA - J Am Med Assoc. 2018;319(15):1554\u201365. https:\/\/doi.org\/10.1001\/jama.2018.2827.","journal-title":"JAMA - J Am Med Assoc."},{"issue":"11","key":"4511_CR9","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1007\/s00192-015-2757-y","volume":"26","author":"R Lykke","year":"2015","unstructured":"Lykke R, Blaak\u00e6r J, Ottesen B, Gimbel H. The indication for hysterectomy as a risk factor for subsequent pelvic organ prolapse repair. Int Urogynecol J. 2015;26(11):1661\u20135. https:\/\/doi.org\/10.1007\/s00192-015-2757-y.","journal-title":"Int Urogynecol J"},{"issue":"1","key":"4511_CR10","doi-asserted-by":"publisher","first-page":"79.e1","DOI":"10.1016\/j.ajog.2012.11.008","volume":"208","author":"M Jonsson Funk","year":"2013","unstructured":"Jonsson Funk M, Edenfield AL, Pate V, Visco AG, Weidner AC, Wu JM. Trends in use of surgical mesh for pelvic organ prolapse. Am J Obstet Gynecol. 2013;208(1):79.e1\u20137. https:\/\/doi.org\/10.1016\/j.ajog.2012.11.008.","journal-title":"Am J Obstet Gynecol"},{"key":"4511_CR11","doi-asserted-by":"publisher","unstructured":"Maher CM, Feiner B, Baessler K, Glazener CMA. Surgical management of pelvic organ prolapse in women: The updated summary version Cochrane review. Int Urogynecol J. 2011;22:1445\u20131457. Springer London. https:\/\/doi.org\/10.1007\/s00192-011-1542-9.","DOI":"10.1007\/s00192-011-1542-9"},{"issue":"1","key":"4511_CR12","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/j.1471-0528.2008.02023.x","volume":"116","author":"B Feiner","year":"2009","unstructured":"Feiner B, Jelovsek JE, Maher C. Efficacy and safety of transvaginal mesh kits in the treatment of prolapse of the vaginal apex: a systematic review. BJOG An Int J Obstet Gynaecol. 2009;116(1):15\u201324. https:\/\/doi.org\/10.1111\/j.1471-0528.2008.02023.x.","journal-title":"BJOG An Int J Obstet Gynaecol"},{"issue":"3","key":"4511_CR13","doi-asserted-by":"publisher","first-page":"230.e1","DOI":"10.1016\/j.ajog.2011.03.046","volume":"205","author":"GB Diwadkar","year":"2011","unstructured":"Diwadkar GB, Barber MD, Feiner B, et al. Predicting the number of women who will undergo incontinence and prolapse surgery, 2010 to 2050. Am J Obstet Gynecol. 2011;205(3):230.e1\u20135. https:\/\/doi.org\/10.1016\/j.ajog.2011.03.046.","journal-title":"Am J Obstet Gynecol"},{"key":"4511_CR14","unstructured":"FDA takes action to protect women\u2019s health, orders manufacturers of surgical mesh intended for transvaginal repair of pelvic organ prolapse to stop selling all devices | FDA. https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-takes-action-protect-womens-health-orders-manufacturers-surgical-mesh-intended-transvaginal. Accessed 14 Jan 2020."},{"issue":"11","key":"4511_CR15","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.1001\/jama.2019.12812","volume":"322","author":"CW Nager","year":"2019","unstructured":"Nager CW, Visco AG, Richter HE, et al. Effect of vaginal mesh hysteropexy vs vaginal hysterectomy with uterosacral ligament suspension on treatment failure in women with uterovaginal prolapse: a randomized clinical trial. JAMA - J Am Med Assoc. 2019;322(11):1054\u201365. https:\/\/doi.org\/10.1001\/jama.2019.12812.","journal-title":"JAMA - J Am Med Assoc"},{"issue":"9","key":"4511_CR16","doi-asserted-by":"publisher","first-page":"1323","DOI":"10.1016\/j.mri.2012.05.001","volume":"30","author":"A Fedorov","year":"2012","unstructured":"Fedorov A, Beichel R, Kalpathy-Cramer J, et al. 3D slicer as an image computing platform for the quantitative imaging network. Magn Reson Imaging. 2012;30(9):1323\u201341. https:\/\/doi.org\/10.1016\/j.mri.2012.05.001.","journal-title":"Magn Reson Imaging"},{"key":"4511_CR17","doi-asserted-by":"publisher","unstructured":"Easley DC, Menon PG, Abramowitch SD, Moalli PA. Inter-observer variability of vaginal wall segmentation from MRI: a statistical shape analysis approach. In: ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE). Vol 3\u20132015. American Society of Mechanical Engineers (ASME); 2015. https:\/\/doi.org\/10.1115\/IMECE2015-53499.","DOI":"10.1115\/IMECE2015-53499"},{"issue":"2","key":"4511_CR18","doi-asserted-by":"publisher","first-page":"344","DOI":"10.1002\/jmri.21847","volume":"30","author":"L Hoyte","year":"2009","unstructured":"Hoyte L, Brubaker L, Fielding JR, et al. Measurements from image-based three dimensional pelvic floor reconstruction: a study of inter- and intraobserver reliability. J Magn Reson Imaging. 2009;30(2):344\u201350. https:\/\/doi.org\/10.1002\/jmri.21847.","journal-title":"J Magn Reson Imaging"},{"issue":"10","key":"4511_CR19","doi-asserted-by":"publisher","first-page":"1247","DOI":"10.1007\/s00192-010-1178-1","volume":"21","author":"JA Tumbarello","year":"2010","unstructured":"Tumbarello JA, Hsu Y, Lewicky-Gaupp C, Rohrer S, DeLancey JOL. Do repetitive Valsalva maneuvers change maximum prolapse on dynamic MRI? Int Urogynecol J. 2010;21(10):1247\u201351. https:\/\/doi.org\/10.1007\/s00192-010-1178-1.","journal-title":"Int Urogynecol J"},{"issue":"8","key":"4511_CR20","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.1007\/s00192-016-2980-1","volume":"27","author":"CW Swenson","year":"2016","unstructured":"Swenson CW, Luo J, Chen L, Ashton-Miller JA, DeLancey JOL. Traction force needed to reproduce physiologically observed uterine movement: technique development, feasibility assessment, and preliminary findings. Int Urogynecol J. 2016;27(8):1227\u201334. https:\/\/doi.org\/10.1007\/s00192-016-2980-1.","journal-title":"Int Urogynecol J"},{"issue":"11","key":"4511_CR21","doi-asserted-by":"publisher","first-page":"1697","DOI":"10.1007\/s00192-018-3755-7","volume":"29","author":"JT Kowalski","year":"2018","unstructured":"Kowalski JT, Mehr A, Cohen E, Bradley CS. Systematic review of definitions for success in pelvic organ prolapse surgery. Int Urogynecol J. 2018;29(11):1697\u2013704. https:\/\/doi.org\/10.1007\/s00192-018-3755-7.","journal-title":"Int Urogynecol J"},{"key":"4511_CR22","doi-asserted-by":"publisher","unstructured":"Meister MRL, Sutcliffe S, Lowder JL. Definitions of apical vaginal support loss: a systematic review. Am J Obstet Gynecol. 2017;216:232.e1\u2013232.e14. Mosby Inc. https:\/\/doi.org\/10.1016\/j.ajog.2016.09.078","DOI":"10.1016\/j.ajog.2016.09.078"},{"key":"4511_CR23","doi-asserted-by":"publisher","unstructured":"J.O. D. The hidden epidemic of pelvic floor dysfunction: achievable goals for improved prevention and treatment. Am J Obstet Gynecol 2005;192(5):1488\u20131495. https:\/\/doi.org\/10.1016\/j.ajog.2004.11.014.","DOI":"10.1016\/j.ajog.2004.11.014"},{"issue":"4","key":"4511_CR24","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s10397-014-0864-2","volume":"11","author":"H Kashihara","year":"2014","unstructured":"Kashihara H, Emmanuelli V, Poncelet E, et al. Comparison of dynamic MRI vaginal anatomical changes after vaginal mesh surgery and laparoscopic sacropexy. Gynecol Surg. 2014;11(4):249\u201356. https:\/\/doi.org\/10.1007\/s10397-014-0864-2.","journal-title":"Gynecol Surg"},{"key":"4511_CR25","doi-asserted-by":"publisher","unstructured":"Kasturi S, Lowman J, Kelvin FM, Akisik F, Terry C, Hale DS. Pelvic magnetic resonance imaging for assessment of the efficacy of the Prolift system for pelvic organ prolapse. Am J Obstet Gynecol. 2010;203:504.e1\u2013504.e5. Mosby Inc. https:\/\/doi.org\/10.1016\/j.ajog.2010.06.034","DOI":"10.1016\/j.ajog.2010.06.034"},{"issue":"10","key":"4511_CR26","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1007\/s00192-018-3807-z","volume":"30","author":"LTS Arenholt","year":"2019","unstructured":"Arenholt LTS, Pedersen BG, Glavind K, Greisen S, Bek KM, Glavind-Kristensen M. Prospective evaluation of paravaginal defect repair with and without apical suspension: a 6-month postoperative follow-up with MRI, clinical examination, and questionnaires. Int Urogynecol J. 2019;30(10):1725\u201333. https:\/\/doi.org\/10.1007\/s00192-018-3807-z.","journal-title":"Int Urogynecol J"}],"container-title":["International Urogynecology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-020-04511-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00192-020-04511-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-020-04511-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T01:26:59Z","timestamp":1630459619000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00192-020-04511-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,1]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["4511"],"URL":"https:\/\/doi.org\/10.1007\/s00192-020-04511-1","relation":{},"ISSN":["0937-3462","1433-3023"],"issn-type":[{"value":"0937-3462","type":"print"},{"value":"1433-3023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,1]]},"assertion":[{"value":"28 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"Pamela A. Moalli: Amphora Medical Inc., consulting; NICHD, research support;Shaniel T. Bowen: None.Steven D. Abramowitch: NICHD: research support;Mark E. Lockhart: JUM, deputy editor, salary and editorial work; Elsevier, book royalties; Oxford Publishers, book royalties;Michael Ham: None.Michael E. Hahn: General Electric, research grant; HealthLytix, consultant;Alison C. Weidner: OBGYN Survey, assistant editor, salary and editorial work; NICHD, research support; Urocure, consultant.Holly E. Richter: IUJ, OG, editorial work and travel reimbursement; Worldwide Fistula Fund, board membership and travel reimbursement; American Urogynecologic Society, Board of Directors, travel reimbursement; Bluewind, DSMB; Renovia, Allergan, NICHD, NIA, research support; UpToDate, licensor and royalties;Charles R. Rardin: FPMRS, editorial board membership; Solace Therapeutics, Pelvalon, Foundation for Female Health Awareness, NICHD, research support;Yuko M. Komesu: Cook-Myosite\u00ae, funding; NICHD, funding.Heidi S. Harvie: None.Beri M. Ridgeway: Coloplast Corp, consulting, education, and travel & lodging;Donna Mazloomdoost: Boston Scientific, research grant.Amanda Shaffer: None.Marie G. Gantz: Boston Scientific, research grant.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}