{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T14:16:04Z","timestamp":1777558564441,"version":"3.51.4"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["CZ.02.2.69\/0.0\/0.0\/19_073\/0016935"],"award-info":[{"award-number":["CZ.02.2.69\/0.0\/0.0\/19_073\/0016935"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Introduction and Hypothesis<\/jats:title>\n                <jats:p>The main risk factor for pelvic floor disorders is vaginal delivery, which may cause levator ani muscle (LAM) injury and denervation. LAM includes pubovisceral muscle (PVM, pubococcygeus), puborectalis muscle (PRM), and iliococcygeus muscle. We hypothesize that primiparous women with low pelvic floor muscle contraction have a reduced PVM cross-sectional area (CSA) compared to nulliparous women.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods (Sample Size and Statistical Approaches)<\/jats:title>\n                <jats:p>This single-centre prospective observational study compared healthy nulliparous (<jats:italic>n<\/jats:italic>\u2009=\u200940) to primiparous (<jats:italic>n<\/jats:italic>\u2009=\u200940) women after vaginal delivery without LAM avulsion and Oxford score\u2009\u2264\u20093. Demographics, questionnaires (ICIQ-UI-SF, OAB-Q-SF, PISQ-12), POP-Q, Oxford score, ultrasound measurements (minimal anteroposterior and lateral diameters, hiatal area, PRM thickness, levator-urethra gap) and magnetic resonance imaging (MRI)\u2014PVM CSA were evaluated. Normality was tested, and an appropriate test was used to compare the groups. Power calculation suggested 40 participants per group.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The primiparous group was older, had a higher BMI, and their hiatal area on ultrasound at contraction was larger compared to the nulliparous group. The CSA of the left-sided PVM (1.15\u2009\u00b1\u20090.50 cm<jats:sup>2<\/jats:sup>) was larger compared to the right side (1.03\u2009\u00b1\u20090.50 cm<jats:sup>2<\/jats:sup>), <jats:italic>p<\/jats:italic>\u2009=\u20090.02 in nulliparous women. The PVM CSA of primiparous women with low Oxford score was reduced compared to nulliparous (0.87\u2009\u00b1\u20090.30 versus 1.09\u2009\u00b1\u20090.50 cm<jats:sup>2<\/jats:sup>, <jats:italic>p<\/jats:italic>\u2009=\u20090.006). The intra-rater reliability for PVM CSA had an ICC of 0.90 and inter-rater ICC of 0.77.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Primiparous women after vaginal delivery with low pelvic floor contraction force had reduced PVM CSA on MRI images compared to nulliparous women.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00192-024-05733-3","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T13:02:53Z","timestamp":1708434173000},"page":"841-848","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Comparison of Cross-Sectional Area of Pubovisceral Muscle in Nulliparous and Primiparous Women"],"prefix":"10.1007","volume":"35","author":[{"given":"Alexandra","family":"Regendova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adela","family":"Samesova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katerina","family":"Zapletalova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabina","family":"Horejskova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzana","family":"Svata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"Hrdouskova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Zapletal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ladislav","family":"Krofta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucie","family":"Hajkova Hympanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"issue":"11","key":"5733_CR1","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1001\/jama.300.11.1311","volume":"300","author":"I Nygaard","year":"2008","unstructured":"Nygaard I. 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