{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T15:09:28Z","timestamp":1782313768577,"version":"3.54.5"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T00:00:00Z","timestamp":1761350400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["DMR-113-079"],"award-info":[{"award-number":["DMR-113-079"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004391","name":"China Medical University Hospital","doi-asserted-by":"publisher","award":["DMR-114-002"],"award-info":[{"award-number":["DMR-114-002"]}],"id":[{"id":"10.13039\/501100004391","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012544","name":"China Medical University, Taiwan","doi-asserted-by":"publisher","award":["CMU113-S-08"],"award-info":[{"award-number":["CMU113-S-08"]}],"id":[{"id":"10.13039\/501100012544","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 114-2320-B-039-040"],"award-info":[{"award-number":["NSTC 114-2320-B-039-040"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020595","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 113-2320-B-039-040"],"award-info":[{"award-number":["NSTC 113-2320-B-039-040"]}],"id":[{"id":"10.13039\/100020595","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"published-print":{"date-parts":[[2026,3]]},"DOI":"10.1007\/s00192-025-06394-6","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T10:53:27Z","timestamp":1761389607000},"page":"673-684","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Intravesical Instillation with Vivo-Morpholino Nerve Growth Factor Antisense Therapy Ameliorates Acute Interstitial Cystitis\/Painful Bladder Syndrome-Related Urinary Frequency in a Rat Model"],"prefix":"10.1007","volume":"37","author":[{"given":"Yung-Hsiang","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Po-Len","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huey-Yi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,10,25]]},"reference":[{"issue":"6","key":"6394_CR1","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1007\/s00192-024-05778-4","volume":"35","author":"B Lemmon","year":"2024","unstructured":"Lemmon B, Kyrgiou M, Mullins E. Khullar v cytokines in bladder pain syndrome: a review of the literature. Int Urogynecol J. 2024;35(6):1119\u201329. https:\/\/doi.org\/10.1007\/s00192-024-05778-4.","journal-title":"Int Urogynecol J"},{"issue":"9","key":"6394_CR2","doi-asserted-by":"publisher","first-page":"1735","DOI":"10.1007\/s00192-024-05844-x","volume":"35","author":"A Soliman","year":"2024","unstructured":"Soliman A, Adel M, Elnagar MA, Elsonbaty S. Hefnawy AE how intravesical platelet-rich plasma can help patients with interstitial cystitis\/bladder pain syndrome: a comprehensive scoping review. Int Urogynecol J. 2024;35(9):1735\u201343. https:\/\/doi.org\/10.1007\/s00192-024-05844-x.","journal-title":"Int Urogynecol J"},{"issue":"2","key":"6394_CR3","first-page":"42","volume":"3","author":"TC Lau","year":"2010","unstructured":"Lau TC. Bengtson JM Management strategies for painful bladder syndrome. Rev Obstet Gynecol. 2010;3(2):42\u20138.","journal-title":"Rev Obstet Gynecol"},{"issue":"1","key":"6394_CR4","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/S0022-5347(05)64847-1","volume":"168","author":"M Leppilahti","year":"2002","unstructured":"Leppilahti M, Tammela TL, Huhtala H, Auvinen A. Prevalence of symptoms related to interstitial cystitis in women: a population based study in Finland. J Urol. 2002;168(1):139\u201343.","journal-title":"J Urol"},{"issue":"6","key":"6394_CR5","doi-asserted-by":"publisher","first-page":"2231","DOI":"10.1097\/01.ju.0000181203.82693.95","volume":"174","author":"MT Rosenberg","year":"2005","unstructured":"Rosenberg MT, Hazzard M. Prevalence of interstitial cystitis symptoms in women: a population based study in the primary care office. J Urol. 2005;174(6):2231\u20134. https:\/\/doi.org\/10.1097\/01.ju.0000181203.82693.95.","journal-title":"J Urol"},{"issue":"1","key":"6394_CR6","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1097\/JU.0000000000002756","volume":"208","author":"JQ Clemens","year":"2022","unstructured":"Clemens JQ, Erickson DR, Varela NP, Lai HH. Diagnosis and treatment of interstitial cystitis\/bladder pain syndrome. J Urol. 2022;208(1):34\u201342. https:\/\/doi.org\/10.1097\/JU.0000000000002756.","journal-title":"J Urol"},{"issue":"1\u20133","key":"6394_CR7","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.ejphar.2013.03.008","volume":"707","author":"C Auge","year":"2013","unstructured":"Auge C, Chene G, Dubourdeau M, Desoubzdanne D, Corman B, Palea S, et al. Relevance of the cyclophosphamide-induced cystitis model for pharmacological studies targeting inflammation and pain of the bladder. Eur J Pharmacol. 2013;707(1\u20133):32\u201340. https:\/\/doi.org\/10.1016\/j.ejphar.2013.03.008.","journal-title":"Eur J Pharmacol"},{"issue":"1","key":"6394_CR8","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/s0022-5347(17)39897-x","volume":"143","author":"CL Parsons","year":"1990","unstructured":"Parsons CL, Boychuk D, Jones S, Hurst R, Callahan H. Bladder surface glycosaminoglycans: an epithelial permeability barrier. J Urol. 1990;143(1):139\u201342. https:\/\/doi.org\/10.1016\/s0022-5347(17)39897-x.","journal-title":"J Urol"},{"issue":"4","key":"6394_CR9","first-page":"e181","volume":"12","author":"J Kaufman","year":"2010","unstructured":"Kaufman J, Tyagi V, Anthony M, Chancellor MB. Tyagi P State of the art in intravesical therapy for lower urinary tract symptoms. Rev Urol. 2010;12(4):e181\u20139.","journal-title":"Rev Urol"},{"issue":"7","key":"6394_CR10","doi-asserted-by":"publisher","first-page":"712","DOI":"10.3109\/02770903.2013.808664","volume":"50","author":"JS Kim","year":"2013","unstructured":"Kim JS, Kang JY, Ha JH, Lee HY, Kim SJ, Kim SC, et al. Expression of nerve growth factor and matrix metallopeptidase-9\/tissue inhibitor of metalloproteinase-1 in asthmatic patients. J Asthma. 2013;50(7):712\u20137. https:\/\/doi.org\/10.3109\/02770903.2013.808664.","journal-title":"J Asthma"},{"issue":"1","key":"6394_CR11","first-page":"4989","volume":"17","author":"BL Jacobs","year":"2010","unstructured":"Jacobs BL, Smaldone MC, Tyagi V, Philips BJ, Jackman SV, Leng WW. Tyagi P Increased nerve growth factor in neurogenic overactive bladder and interstitial cystitis patients. Can J Urol. 2010;17(1):4989\u201394.","journal-title":"Can J Urol"},{"issue":"9","key":"6394_CR12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0044687","volume":"7","author":"HT Liu","year":"2012","unstructured":"Liu HT, Kuo HC. Increased urine and serum nerve growth factor levels in interstitial cystitis suggest chronic inflammation is involved in the pathogenesis of disease. PLoS ONE. 2012;7(9):e44687. https:\/\/doi.org\/10.1371\/journal.pone.0044687.","journal-title":"PLoS ONE"},{"issue":"3","key":"6394_CR13","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.jpain.2004.01.001","volume":"5","author":"K Lamb","year":"2004","unstructured":"Lamb K, Gebhart GF, Bielefeldt K. Increased nerve growth factor expression triggers bladder overactivity. J Pain. 2004;5(3):150\u20136. https:\/\/doi.org\/10.1016\/j.jpain.2004.01.001.","journal-title":"J Pain"},{"issue":"1","key":"6394_CR14","doi-asserted-by":"publisher","first-page":"1072","DOI":"10.1186\/s40064-016-2719-y","volume":"5","author":"W Chen","year":"2016","unstructured":"Chen W, Ye DY, Han DJ, Fu GQ, Zeng X, Lin W. Liang y elevated level of nerve growth factor in the bladder pain syndrome\/interstitial cystitis: a meta-analysis. Springerplus. 2016;5(1):1072. https:\/\/doi.org\/10.1186\/s40064-016-2719-y.","journal-title":"Springerplus"},{"issue":"1","key":"6394_CR15","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1073\/pnas.75.1.285","volume":"75","author":"ML Stephenson","year":"1978","unstructured":"Stephenson ML. Zamecnik PC inhibition of Rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci U S A. 1978;75(1):285\u20138. https:\/\/doi.org\/10.1073\/pnas.75.1.285.","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"6","key":"6394_CR16","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1038\/eye.2008.86","volume":"22","author":"H Dadgostar","year":"2008","unstructured":"Dadgostar H, Waheed N. The evolving role of vascular endothelial growth factor inhibitors in the treatment of neovascular age-related macular degeneration. Eye (Lond). 2008;22(6):761\u20137. https:\/\/doi.org\/10.1038\/eye.2008.86.","journal-title":"Eye (Lond)"},{"issue":"3","key":"6394_CR17","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1089\/oli.1.2000.10.163","volume":"10","author":"RM Hudziak","year":"2000","unstructured":"Hudziak RM, Summerton J, Weller DD, Iversen PL. Antiproliferative effects of steric blocking phosphorodiamidate morpholino antisense agents directed against c-myc. Antisense Nucleic Acid Drug Dev. 2000;10(3):163\u201376. https:\/\/doi.org\/10.1089\/oli.1.2000.10.163.","journal-title":"Antisense Nucleic Acid Drug Dev"},{"issue":"2","key":"6394_CR18","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1038\/79951","volume":"26","author":"A Nasevicius","year":"2000","unstructured":"Nasevicius A, Ekker sc. Effective targeted gene \u2018knockdown\u2019 in zebrafish. Nat Genet. 2000;26(2):216\u201320. https:\/\/doi.org\/10.1038\/79951.","journal-title":"Nat Genet"},{"issue":"3","key":"6394_CR19","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.3390\/molecules14031304","volume":"14","author":"JD Moulton","year":"2009","unstructured":"Moulton JD. Jiang S gene knockdowns in adult animals: PPMOs and vivo-morpholinos. Molecules. 2009;14(3):1304\u201323. https:\/\/doi.org\/10.3390\/molecules14031304.","journal-title":"Molecules"},{"issue":"5","key":"6394_CR20","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1038\/mt.2009.38","volume":"17","author":"B Wu","year":"2009","unstructured":"Wu B, Li Y, Morcos PA, Doran TJ, Lu P, Lu QL. Octa-guanidine morpholino restores dystrophin expression in cardiac and skeletal muscles and ameliorates pathology in dystrophic mdx mice. Mol Ther. 2009;17(5):864\u201371. https:\/\/doi.org\/10.1038\/mt.2009.38.","journal-title":"Mol Ther"},{"issue":"3","key":"6394_CR21","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1007\/s00281-018-0674-0","volume":"40","author":"LA Birder","year":"2018","unstructured":"Birder LA. Kullmann fa role of neurogenic inflammation in local communication in the visceral mucosa. Semin Immunopathol. 2018;40(3):261\u201379. https:\/\/doi.org\/10.1007\/s00281-018-0674-0.","journal-title":"Semin Immunopathol"},{"key":"6394_CR22","doi-asserted-by":"publisher","first-page":"1305","DOI":"10.3389\/fphar.2020.01305","volume":"11","author":"C Auge","year":"2020","unstructured":"Auge C, Game X, Vergnolle N, Lluel P. Chabot s characterization and validation of a chronic model of cyclophosphamide-induced interstitial cystitis\/bladder pain syndrome in rats. Front Pharmacol. 2020;11:1305. https:\/\/doi.org\/10.3389\/fphar.2020.01305.","journal-title":"Front Pharmacol"},{"issue":"8","key":"6394_CR23","doi-asserted-by":"publisher","first-page":"1659","DOI":"10.1002\/nau.21180","volume":"30","author":"M Boudes","year":"2011","unstructured":"Boudes M, Uvin P, Kerselaers S, Vennekens R, Voets T, De Ridder D. Functional characterization of a chronic cyclophosphamide-induced overactive bladder model in mice. Neurourol Urodyn. 2011;30(8):1659\u201365. https:\/\/doi.org\/10.1002\/nau.21180.","journal-title":"Neurourol Urodyn"},{"issue":"3","key":"6394_CR24","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1002\/nau.20777","volume":"29","author":"C Saitoh","year":"2010","unstructured":"Saitoh C, Yokoyama H, Chancellor MB, de Groat WC, Yoshimura N. Comparison of voiding function and nociceptive behavior in two rat models of cystitis induced by cyclophosphamide or acetone. Neurourol Urodyn. 2010;29(3):501\u20135. https:\/\/doi.org\/10.1002\/nau.20777.","journal-title":"Neurourol Urodyn"},{"key":"6394_CR25","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2023.1232017","volume":"14","author":"C Tay","year":"2023","unstructured":"Tay C. Animal models of interstitial cystitis\/bladder pain syndrome. Front Physiol. 2023;14:1232017. https:\/\/doi.org\/10.3389\/fphys.2023.1232017.","journal-title":"Front Physiol"},{"issue":"8","key":"6394_CR26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0104216","volume":"9","author":"T Okinami","year":"2014","unstructured":"Okinami T, Imamura M, Nishikawa N, Negoro H, Sugino Y, Yoshimura K, et al. Altered detrusor gap junction communications induce storage symptoms in bladder inflammation: a mouse cyclophosphamide-induced model of cystitis. PLoS ONE. 2014;9(8):e104216. https:\/\/doi.org\/10.1371\/journal.pone.0104216.","journal-title":"PLoS ONE"},{"key":"6394_CR27","doi-asserted-by":"publisher","unstructured":"Renzi A, DeMorrow S, Onori P, Carpino G, Mancinelli R, Meng F, et al. Modulation of the biliary expression of arylalkylamine N-acetyltransferase alters the autocrine proliferative responses of cholangiocytes in rats. Hepatology. 2013;57(3):1130\u201341. https:\/\/doi.org\/10.1002\/hep.26105.","DOI":"10.1002\/hep.26105"},{"issue":"1","key":"6394_CR28","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.ejogrb.2013.08.034","volume":"171","author":"HY Chen","year":"2013","unstructured":"Chen HY, Chen CJ, Lin YN, Chen YH, Chen WC, Chen CM. Proteomic analysis related to stress urinary incontinence following vaginal trauma in female mice. Eur J Obstet Gynecol Reprod Biol. 2013;171(1):171\u20139. https:\/\/doi.org\/10.1016\/j.ejogrb.2013.08.034.","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"5","key":"6394_CR29","doi-asserted-by":"publisher","first-page":"1977","DOI":"10.1021\/jf062945r","volume":"55","author":"FY Lin","year":"2007","unstructured":"Lin FY, Chen YH, Chen YL, Wu TC, Li CY, Chen JW, et al. Ginkgo biloba extract inhibits endotoxin-induced human aortic smooth muscle cell proliferation via suppression of toll-like receptor 4 expression and NADPH oxidase activation. J Agric Food Chem. 2007;55(5):1977\u201384. https:\/\/doi.org\/10.1021\/jf062945r.","journal-title":"J Agric Food Chem"},{"issue":"3","key":"6394_CR30","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1002\/jcb.10151","volume":"85","author":"SJ Lin","year":"2002","unstructured":"Lin SJ, Yang TH, Chen YH, Chen JW, Kwok CF, Shiao MS, et al. Effects of Ginkgo biloba extract on the proliferation of vascular smooth muscle cells in vitro and on intimal thickening and interleukin-1beta expression after balloon injury in cholesterol-fed rabbits in vivo. J Cell Biochem. 2002;85(3):572\u201382. https:\/\/doi.org\/10.1002\/jcb.10151.","journal-title":"J Cell Biochem"},{"key":"6394_CR31","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13127","author":"K Dogishi","year":"2017","unstructured":"Dogishi K, Okamoto K, Majima T, Konishi-Shiotsu S, Homan T, Kodera M, et al. A rat long-lasting cystitis model induced by intravesical injection of hydrogen peroxide. Physiol Rep. 2017. https:\/\/doi.org\/10.14814\/phy2.13127.","journal-title":"Physiol Rep"},{"issue":"1","key":"6394_CR32","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1002\/nau.25095","volume":"42","author":"Y Tokita","year":"2023","unstructured":"Tokita Y, Sugaya K, Nishijima S, Tsuchiya N, Hamaguchi M, Yamamoto H. Choreito, a kampo medicine attenuates detrusor overactivity and bladder pain symptoms in rat tranilast-induced interstitial cystitis\/bladder pain syndrome-like model. Neurourol Urodyn. 2023;42(1):56\u201364. https:\/\/doi.org\/10.1002\/nau.25095.","journal-title":"Neurourol Urodyn"},{"issue":"2\u20133","key":"6394_CR33","first-page":"e69","volume":"12","author":"HC Kuo","year":"2010","unstructured":"Kuo HC, Liu HT. Chancellor MB Can urinary nerve growth factor be a biomarker for overactive bladder? Rev Urol. 2010;12(2\u20133):e69-77.","journal-title":"Rev Urol"},{"issue":"3","key":"6394_CR34","doi-asserted-by":"publisher","first-page":"R534","DOI":"10.1152\/ajpregu.00367.2009","volume":"298","author":"B Schnegelsberg","year":"2010","unstructured":"Schnegelsberg B, Sun TT, Cain G, Bhattacharya A, Nunn PA, Ford AP, et al. Cockayne DA Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function. Am J Physiol Regul Integr Comp Physiol. 2010;298(3):R534\u201347. https:\/\/doi.org\/10.1152\/ajpregu.00367.2009.","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"issue":"2","key":"6394_CR35","doi-asserted-by":"publisher","first-page":"354","DOI":"10.1016\/j.jneumeth.2011.10.009","volume":"203","author":"KJ Reissner","year":"2012","unstructured":"Reissner KJ, Sartor GC, Vazey EM, Dunn TE, Aston-Jones G, Kalivas PW. Use of vivo-morpholinos for control of protein expression in the adult rat brain. J Neurosci Methods. 2012;203(2):354\u201360. https:\/\/doi.org\/10.1016\/j.jneumeth.2011.10.009.","journal-title":"J Neurosci Methods"},{"issue":"2","key":"6394_CR36","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.juro.2013.02.090","volume":"190","author":"M Kashyap","year":"2013","unstructured":"Kashyap M, Kawamorita N, Tyagi V, Sugino Y, Chancellor M, Yoshimura N, et al. Down-regulation of nerve growth factor expression in the bladder by antisense oligonucleotides as new treatment for overactive bladder. J Urol. 2013;190(2):757\u201364. https:\/\/doi.org\/10.1016\/j.juro.2013.02.090.","journal-title":"J Urol"},{"issue":"4","key":"6394_CR37","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1007\/s12031-016-0774-z","volume":"59","author":"BM Girard","year":"2016","unstructured":"Girard BM, Malley S, May V, Vizzard MA. Effects of CYP-induced cystitis on growth factors and associated receptor expression in micturition pathways in mice with chronic overexpression of NGF in urothelium. J Mol Neurosci. 2016;59(4):531\u201343. https:\/\/doi.org\/10.1007\/s12031-016-0774-z.","journal-title":"J Mol Neurosci"},{"issue":"2","key":"6394_CR38","doi-asserted-by":"publisher","first-page":"189","DOI":"10.22074\/cellj.2016.4313","volume":"18","author":"Y Mortazavi","year":"2016","unstructured":"Mortazavi Y, Sheikhsaran F, Khamisipour GK, Soleimani M, Teimuri A, Shokri S. The evaluation of nerve growth factor over expression on neural lineage specific genes in human mesenchymal stem cells. Cell Journal (Yakhteh). 2016;18(2):189\u201396. https:\/\/doi.org\/10.22074\/cellj.2016.4313.","journal-title":"Cell Journal (Yakhteh)"},{"key":"6394_CR39","doi-asserted-by":"publisher","first-page":"1483548","DOI":"10.3389\/fphar.2025.1483548","volume":"16","author":"I Anjum","year":"2025","unstructured":"Anjum I, Nasir A, Naseer F, Ibrahim A, Rehman B, Bashir F. Tul ain q exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review. Front Pharmacol. 2025;16:1483548. https:\/\/doi.org\/10.3389\/fphar.2025.1483548.","journal-title":"Front Pharmacol"},{"issue":"3","key":"6394_CR40","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1016\/j.euf.2019.06.006","volume":"5","author":"T Antunes-Lopes","year":"2019","unstructured":"Antunes-Lopes T, Cruz F. Urinary biomarkers in overactive bladder: revisiting the evidence in 2019. Eur Urol Focus. 2019;5(3):329\u201336. https:\/\/doi.org\/10.1016\/j.euf.2019.06.006.","journal-title":"Eur Urol Focus"},{"issue":"3","key":"6394_CR41","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1097\/JU.0000000000001031","volume":"204","author":"HH Lai","year":"2020","unstructured":"Lai HH, Pickersgill NA, Vetter JM. Hunner lesion phenotype in interstitial cystitis\/bladder pain syndrome: a systematic review and meta-analysis. J Urol. 2020;204(3):518\u201323. https:\/\/doi.org\/10.1097\/JU.0000000000001031.","journal-title":"J Urol"},{"key":"6394_CR42","doi-asserted-by":"publisher","unstructured":"Ismawati, Saryono, Mukhyarjon, Romus I, Putri VD, Yanti S, Dyna F, Adesti NI Effect of inulin from dahlia tubers (Dahlia variabilis) extract on insulitis severity and insulin expression in diabetic rats. Biomedicine (Taipei). 2024;14(3):31\u201339. https:\/\/doi.org\/10.37796\/2211-8039.1460.","DOI":"10.37796\/2211-8039.1460"},{"key":"6394_CR43","doi-asserted-by":"publisher","unstructured":"Mata-Bermudez A, Trejo-Chavez R, Martinez-Vargas M, Perez-Arredondo A, de Los Angeles Martinez-Cardenas M, Diaz-Ruiz A, Rios C, Romero-Sanchez HA, Martinez-Antonio A, Navarro L Effect of Mucuna pruriens seed extract on depression-like behavior derived from mild traumatic brain injury in rats. Biomedicine (Taipei). 2024;14(3):23\u201330. https:\/\/doi.org\/10.37796\/2211-8039.1461.","DOI":"10.37796\/2211-8039.1461"},{"issue":"1","key":"6394_CR44","doi-asserted-by":"publisher","first-page":"10","DOI":"10.37796\/2211-8039.1433","volume":"14","author":"RD Palmer","year":"2024","unstructured":"Palmer RD. Biomedicines in longevity and aging the quest to resist biological decline. Biomedicine (Taipei). 2024;14(1):10\u20139. https:\/\/doi.org\/10.37796\/2211-8039.1433.","journal-title":"Biomedicine (Taipei)"}],"container-title":["International Urogynecology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-025-06394-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00192-025-06394-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-025-06394-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T13:17:44Z","timestamp":1774703864000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00192-025-06394-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,25]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["6394"],"URL":"https:\/\/doi.org\/10.1007\/s00192-025-06394-6","relation":{},"ISSN":["0937-3462","1433-3023"],"issn-type":[{"value":"0937-3462","type":"print"},{"value":"1433-3023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,25]]},"assertion":[{"value":"12 March 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 October 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The processes of the animal study received consent from the ethical committee of the Institutional Animal Care and Use Committee of China Medical University (Reference number: CMUIACUC-2022\u2013190, 28 December 2021), Taichung, Taiwan.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"None.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}