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Although there is evidence supporting the use of photobiomodulation (PBM) for pain relief and wound healing in various conditions, there is a lack of studies on its effect on these lacerations. Our hypothesis is that PBM aids in pain management and healing in perineal lacerations\/episiotomies in hospitalized women.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>A randomized, controlled, double-blind clinical trial in women with grade I\/II lacerations and\/or episiotomy, assigned to the intervention group (660\u00a0nm; 4\u00a0J) or placebo group (device turned off). Primary outcome was perineal pain at rest and during movements, measured using the numeric rating scale. Secondary outcome was healing, measured using the REEDA (redness, edema, ecchymosis, discharge, approximation) scale. Additionally, in-hospital analgesic consumption, self-perception of perineal laceration healing, and satisfaction with the intervention were analyzed. Analysis performed pre-intervention (6\u201312\u00a0h postpartum), post-intervention 1 (6\u201312\u00a0h post-first intervention), post-intervention 2 (12\u201318\u00a0h post-first intervention), and follow-up (7\u201315\u00a0days postpartum). Analysis was performed on an intention-to-treat basis using the Mann\u2013Whitney test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 59 women participated (intervention 30; placebo 29), most of whom were primiparous. The intragroup analysis shows a reduction in perineal pain during rest and movements, with improved healing in both groups. No difference was observed in intergroup analysis. The intervention group consumed fewer analgesics and had a longer interval between doses than the placebo group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Photobiomodulation (660\u00a0nm; 4\u00a0J) applied within 24\u00a0h postpartum, did not result in clinical improvement in pain or healing in women with perineal lacerations\/episiotomies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00192-026-06686-5","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T12:25:49Z","timestamp":1781699149000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Photobiomodulation for Pain, Healing, and Analgesic Use after Perineal Lacerations: A Double-Blind Randomized Controlled Trial"],"prefix":"10.1007","author":[{"given":"Thais","family":"de Castro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00edza Helena","family":"Viana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Botelho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00edgia Sousa","family":"Marino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,17]]},"reference":[{"key":"6686_CR1","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1055\/s-0041-1735227","volume":"43","author":"LHH Domenighi","year":"2021","unstructured":"Domenighi LHH, Weinmann ARM, Haeffner LSB, Feltrin ML. 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The present study was conducted with the support of the Research Foundation of the State of Minas Gerais, through the Federal University of Alfenas (UNIFAL-MG), and with the support of the Coordination for the Improvement of Higher Education Personnel \u2013 Brazil \u2013 Funding code 001. Data are available upon reasonable request by email to the corresponding author.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Aspects"}}]}}