{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T14:04:15Z","timestamp":1791468255596,"version":"4.3.4"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["20K11158"],"award-info":[{"award-number":["20K11158"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K11420"],"award-info":[{"award-number":["22K11420"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25K14507"],"award-info":[{"award-number":["25K14507"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["25K14404"],"award-info":[{"award-number":["25K14404"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s00192-026-06703-7","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T12:53:31Z","timestamp":1778936011000},"page":"3053-3062","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Low-Intensity Extracorporeal Shock Wave Therapy Restores Passive Urethral Closure Mechanism in Vaginal Distension Rat Model"],"prefix":"10.1007","volume":"37","author":[{"given":"Takahiro","family":"Akimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asuka","family":"Ashikari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masahiro","family":"Kurobe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gakuya","family":"Takamatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Akiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruki","family":"Kume","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3669-4510","authenticated-orcid":false,"given":"Minoru","family":"Miyazato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,16]]},"reference":[{"key":"6703_CR1","doi-asserted-by":"publisher","first-page":"747","DOI":"10.1111\/iju.15454","volume":"31","author":"T Mitsui","year":"2024","unstructured":"Mitsui T, Sekido N, Masumori N, Haga N, Omae K, Saito M, et al. Prevalence and impact on daily life of lower urinary tract symptoms in Japan: results of the 2023 Japan Community Health Survey (JaCS 2023). Int J Urol. 2024;31:747\u201354. https:\/\/doi.org\/10.1111\/iju.15454","journal-title":"Int J Urol"},{"key":"6703_CR2","doi-asserted-by":"publisher","first-page":"Cd007471","DOI":"10.1002\/14651858.CD007471.pub4","volume":"5","author":"SJ Woodley","year":"2020","unstructured":"Woodley SJ, Lawrenson P, Boyle R, Cody JD, M\u00f8rkved S, Kernohan A, et al. Pelvic floor muscle training for preventing and treating urinary and faecal incontinence in antenatal and postnatal women. Cochrane Database Syst Rev. 2020;5:Cd007471. https:\/\/doi.org\/10.1002\/14651858.CD007471.pub4","journal-title":"Cochrane Database Syst Rev"},{"key":"6703_CR3","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1007\/s11934-024-01205-9","volume":"25","author":"SS Tabei","year":"2024","unstructured":"Tabei SS, Baas W, Mahdy A. Pharmacotherapy in stress urinary incontinence; a literature review. Curr Urol Rep. 2024;25:141\u20138. https:\/\/doi.org\/10.1007\/s11934-024-01205-9","journal-title":"Curr Urol Rep"},{"key":"6703_CR4","doi-asserted-by":"publisher","first-page":"1091","DOI":"10.1097\/ju.0000000000003435","volume":"209","author":"KC Kobashi","year":"2023","unstructured":"Kobashi KC, Vasavada S, Bloschichak A, Hermanson L, Kaczmarek J, Kim SK, et al. Updates to surgical treatment of female stress urinary incontinence (SUI): AUA\/SUFU guideline (2023). J Urol. 2023;209:1091\u20138. https:\/\/doi.org\/10.1097\/ju.0000000000003435","journal-title":"J Urol"},{"key":"6703_CR5","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1111\/j.1442-2042.2012.02976.x","volume":"19","author":"N Yoshimura","year":"2012","unstructured":"Yoshimura N, Miyazato M. Neurophysiology and therapeutic receptor targets for stress urinary incontinence. Int J Urol. 2012;19:524\u201337. https:\/\/doi.org\/10.1111\/j.1442-2042.2012.02976.x","journal-title":"Int J Urol"},{"key":"6703_CR6","doi-asserted-by":"publisher","first-page":"2286","DOI":"10.1016\/j.juro.2008.01.098","volume":"179","author":"JO DeLancey","year":"2008","unstructured":"DeLancey JO, Trowbridge ER, Miller JM, Morgan DM, Guire K, Fenner DE, et al. Stress urinary incontinence: relative importance of urethral support and urethral closure pressure. J Urol. 2008;179:2286\u201390. https:\/\/doi.org\/10.1016\/j.juro.2008.01.098","journal-title":"J Urol"},{"key":"6703_CR7","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.ejogrb.2019.01.012","volume":"234","author":"R Gong","year":"2019","unstructured":"Gong R, Xia Z. Collagen changes in pelvic support tissues in women with pelvic organ prolapse. Eur J Obstet Gynecol Reprod Biol. 2019;234:185\u20139. https:\/\/doi.org\/10.1016\/j.ejogrb.2019.01.012","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"6703_CR8","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1186\/s13104-020-05430-6","volume":"14","author":"A Ashikari","year":"2021","unstructured":"Ashikari A, Suda T, Miyazato M. Collagen type 1A1, type 3A1, and LOXL1\/4 polymorphisms as risk factors of pelvic organ prolapse. BMC Res Notes. 2021;14:15. https:\/\/doi.org\/10.1186\/s13104-020-05430-6","journal-title":"BMC Res Notes"},{"key":"6703_CR9","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1016\/j.ejogrb.2012.04.012","volume":"163","author":"HY Chen","year":"2012","unstructured":"Chen HY, Lin YN, Chen YH, Chen WC. Stress urinary incontinence following vaginal trauma involves remodeling of urethral connective tissue in female mice. Eur J Obstet Gynecol Reprod Biol. 2012;163:224\u20139. https:\/\/doi.org\/10.1016\/j.ejogrb.2012.04.012","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"6703_CR10","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering12040373","volume":"12","author":"D De Vicari","year":"2025","unstructured":"De Vicari D, Barba M, Costa C, Cola A, Frigerio M. Assessment of urethral elasticity by shear wave elastography: a novel parameter bridging a gap between hypermobility and ISD in female stress urinary incontinence. Bioengineering Basel. 2025;12:373. https:\/\/doi.org\/10.3390\/bioengineering12040373.","journal-title":"Bioengineering Basel"},{"key":"6703_CR11","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22157844","volume":"22","author":"JS Holsapple","year":"2021","unstructured":"Holsapple JS, Cooper B, Berry SH, Staniszewska A, Dickson BM, Taylor JA, et al. Low intensity shockwave treatment modulates macrophage functions beneficial to healing chronic wounds. Int J Mol Sci. 2021;22:7844. https:\/\/doi.org\/10.3390\/ijms22157844.","journal-title":"Int J Mol Sci"},{"key":"6703_CR12","doi-asserted-by":"publisher","first-page":"3773","DOI":"10.1007\/s11255-024-04136-z","volume":"56","author":"K Kawase","year":"2024","unstructured":"Kawase K, Kamijo TC, Kusakabe N, Nakane K, Koie T, Miyazato M. Effects of low-intensity extracorporeal shock wave on bladder and urethral dysfunction in spinal cord injured rats. Int Urol Nephrol. 2024;56:3773\u201381. https:\/\/doi.org\/10.1007\/s11255-024-04136-z","journal-title":"Int Urol Nephrol"},{"key":"6703_CR13","doi-asserted-by":"publisher","first-page":"187.e1","DOI":"10.1016\/j.urology.2020.03.035","volume":"141","author":"X Zhang","year":"2020","unstructured":"Zhang X, Ruan Y, Wu AK, Zaid U, Villalta JD, Wang G, et al. Delayed treatment with low-intensity extracorporeal shock wave therapy in an irreversible rat model of stress urinary incontinence. Urology. 2020;141:187.e1-187.e7. https:\/\/doi.org\/10.1016\/j.urology.2020.03.035.","journal-title":"Urology"},{"key":"6703_CR14","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s11255-023-03770-3","volume":"56","author":"N Kusakabe","year":"2024","unstructured":"Kusakabe N, Kamijo TC, Wada N, Chiba H, Shinohara N, Miyazato M. Effects of low-intensity extracorporeal shock wave therapy on lipopolysaccharide cystitis in a rat model of interstitial cystitis\/bladder pain syndrome. Int Urol Nephrol. 2024;56:77\u201386. https:\/\/doi.org\/10.1007\/s11255-023-03770-3","journal-title":"Int Urol Nephrol"},{"key":"6703_CR15","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-025-04814-6","author":"TC Kamijo","year":"2025","unstructured":"Kamijo TC, Kurobe M, Akimoto T, Miyazato M. Low-intensity energy shock wave therapy modulates bladder function and anxiety-like behavior in maternal separation rats. Int Urol Nephrol. 2025. https:\/\/doi.org\/10.1007\/s11255-025-04814-6","journal-title":"Int Urol Nephrol"},{"key":"6703_CR16","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-62471-4","volume":"10","author":"CY Long","year":"2020","unstructured":"Long CY, Lin KL, Lee YC, Chuang SM, Lu JH, Wu BN, et al. Therapeutic effects of low intensity extracorporeal low energy shock wave therapy (LiESWT) on stress urinary incontinence. Sci Rep. 2020;10:5818. https:\/\/doi.org\/10.1038\/s41598-020-62471-4.","journal-title":"Sci Rep"},{"key":"6703_CR17","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57090947","volume":"57","author":"KL Lin","year":"2021","unstructured":"Lin KL, Chueh KS, Lu JH, Chuang SM, Wu BN, Lee YC, et al. Low intensity extracorporeal shock wave therapy as a novel treatment for stress urinary incontinence: a randomized-controlled clinical study. Medicina Kaunas. 2021;57:947. https:\/\/doi.org\/10.3390\/medicina57090947.","journal-title":"Medicina Kaunas"},{"key":"6703_CR18","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18020433","volume":"18","author":"B Wang","year":"2017","unstructured":"Wang B, Ning H, Reed-Maldonado AB, Zhou J, Ruan Y, Zhou T, et al. Low-intensity extracorporeal shock wave therapy enhances brain-derived neurotrophic factor expression through PERK\/ATF4 signaling pathway. Int J Mol Sci. 2017;18:433. https:\/\/doi.org\/10.3390\/ijms18020433.","journal-title":"Int J Mol Sci"},{"key":"6703_CR19","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2015.183","volume":"6","author":"Z Liu","year":"2015","unstructured":"Liu Z, Lv Y, Zhao N, Guan G, Wang J. Protein kinase R-like ER kinase and its role in endoplasmic reticulum stress-decided cell fate. Cell Death Dis. 2015;6:e1822. https:\/\/doi.org\/10.1038\/cddis.2015.183.","journal-title":"Cell Death Dis"},{"key":"6703_CR20","doi-asserted-by":"publisher","first-page":"1884","DOI":"10.1152\/japplphysiol.01071.2004","volume":"98","author":"MS Damaser","year":"2005","unstructured":"Damaser MS, Whitbeck C, Chichester P, Levin RM. Effect of vaginal distension on blood flow and hypoxia of urogenital organs of the female rat. J Appl Physiol. 2005;98:1884\u201390. https:\/\/doi.org\/10.1152\/japplphysiol.01071.2004","journal-title":"J Appl Physiol"},{"key":"6703_CR21","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1111\/j.1447-0756.2012.01959.x","volume":"39","author":"J Huang","year":"2013","unstructured":"Huang J, Cheng M, Ding Y, Chen L, Hua K. Modified vaginal dilation rat model for postpartum stress urinary incontinence. J Obstet Gynaecol Res. 2013;39:256\u201363. https:\/\/doi.org\/10.1111\/j.1447-0756.2012.01959.x","journal-title":"J Obstet Gynaecol Res"},{"key":"6703_CR22","doi-asserted-by":"publisher","first-page":"S7","DOI":"10.21037\/tau.2017.12.36","volume":"7","author":"AK Wu","year":"2018","unstructured":"Wu AK, Zhang X, Wang J, Ning H, Zaid U, Villalta JD, et al. Treatment of stress urinary incontinence with low-intensity extracorporeal shock wave therapy in a vaginal balloon dilation induced rat model. Transl Androl Urol. 2018;7:S7-16. https:\/\/doi.org\/10.21037\/tau.2017.12.36.","journal-title":"Transl Androl Urol"},{"key":"6703_CR23","doi-asserted-by":"publisher","first-page":"1605","DOI":"10.1002\/nau.23518","volume":"37","author":"A Ashikari","year":"2018","unstructured":"Ashikari A, Miyazato M, Kimura R, Oshiro T, Saito S. The effect of tramadol on sneeze-induced urethral continence reflex through \u03bc-opioid receptors in the spinal cord in rats. Neurourol Urodyn. 2018;37:1605\u201311. https:\/\/doi.org\/10.1002\/nau.23518","journal-title":"Neurourol Urodyn"},{"key":"6703_CR24","doi-asserted-by":"publisher","first-page":"F1089","DOI":"10.1152\/ajprenal.00230.2017","volume":"313","author":"S Yoshikawa","year":"2017","unstructured":"Yoshikawa S, Sumino Y, Kwon J, Suzuki T, Kitta T, Miyazato M, et al. Effects of multiple simulated birth traumas on urethral continence function in rats. Am J Physiol Renal Physiol. 2017;313:F1089-96. https:\/\/doi.org\/10.1152\/ajprenal.00230.2017.","journal-title":"Am J Physiol Renal Physiol"},{"key":"6703_CR25","doi-asserted-by":"publisher","first-page":"F434","DOI":"10.1152\/ajprenal.00038.2004","volume":"287","author":"I Kamo","year":"2004","unstructured":"Kamo I, Cannon TW, Conway DA, Torimoto K, Chancellor MB, de Groat WC, et al. The role of bladder-to-urethral reflexes in urinary continence mechanisms in rats. Am J Physiol Renal Physiol. 2004;287:F434-441. https:\/\/doi.org\/10.1152\/ajprenal.00038.2004.","journal-title":"Am J Physiol Renal Physiol"},{"issue":"1","key":"6703_CR26","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-01200-x","volume":"11","author":"JL Palacios","year":"2021","unstructured":"Palacios JL, Ju\u00e1rez R, Mirto-Aguilar N, Munoz A, Damaser MS, Cruz Y. Time course for urethral neuromuscular reestablishment and its facilitated recovery by transcutaneous neuromodulation after simulated birth trauma in rats. Sci Rep. 2021;11(1):21591. https:\/\/doi.org\/10.1038\/s41598-021-01200-x.","journal-title":"Sci Rep"},{"key":"6703_CR27","doi-asserted-by":"publisher","first-page":"F303","DOI":"10.1152\/ajprenal.00214.2019","volume":"317","author":"MG Dalghi","year":"2019","unstructured":"Dalghi MG, Clayton DR, Ruiz WG, Al-Bataineh MM, Satlin LM, Kleyman TR, et al. Expression and distribution of PIEZO1 in the mouse urinary tract. Am J Physiol Renal Physiol. 2019;317:F303-f321. https:\/\/doi.org\/10.1152\/ajprenal.00214.2019.","journal-title":"Am J Physiol Renal Physiol"},{"key":"6703_CR28","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25094927","volume":"25","author":"KS Chueh","year":"2024","unstructured":"Chueh KS, Juan TJ, Lu JH, Wu BN, Lin RJ, Mao JW, et al. Low-intensity extracorporeal shock wave therapy ameliorates detrusor hyperactivity with impaired contractility via transient potential vanilloid channels: a rat model for ovarian hormone deficiency. Int J Mol Sci. 2024;25:4927. https:\/\/doi.org\/10.3390\/ijms25094927.","journal-title":"Int J Mol Sci"}],"container-title":["International Urogynecology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-026-06703-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00192-026-06703-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-026-06703-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:36:14Z","timestamp":1791466574000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00192-026-06703-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,16]]},"references-count":28,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["6703"],"URL":"https:\/\/doi.org\/10.1007\/s00192-026-06703-7","relation":{},"ISSN":["0937-3462","1433-3023"],"issn-type":[{"value":"0937-3462","type":"print"},{"value":"1433-3023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,16]]},"assertion":[{"value":"26 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All experimental procedures were performed using a protocol (A2021041) approved by the Institutional Animal Care and Use Committee of the University of the Ryukyus in compliance with the ARRIVE guidelines (\n                      \n                      ). All efforts were made to minimize suffering and the number of rats used in the experiment.","order":1,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","label":"Conflicts of Interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}