{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:16:08Z","timestamp":1789992968349,"version":"4.0.1"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Urogynecol J"],"DOI":"10.1007\/s00192-026-06911-1","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:51:34Z","timestamp":1789991494000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Can Preadmission Inflammatory Markers Inform Episiotomy Wound Dehiscence Risk? A Case\u2013Control Study in Primiparous Women"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7651-3409","authenticated-orcid":false,"given":"Aybekcan","family":"Batman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-5035-0594","authenticated-orcid":false,"given":"Elif \u00d6zden Kural","family":"Ta\u015fs\u0131nd\u0131ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5630-1257","authenticated-orcid":false,"given":"Enes","family":"Sara\u00e7","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9185-5391","authenticated-orcid":false,"given":"Yi\u011fit Mert","family":"Bayrak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2215-1198","authenticated-orcid":false,"given":"Ozan","family":"Karadeniz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"issue":"6","key":"6911_CR1","doi-asserted-by":"publisher","first-page":"644","DOI":"10.1080\/07399332.2018.1445253","volume":"39","author":"C Clesse","year":"2018","unstructured":"Clesse C, Lighezzolo-Alnot J, De Lavergne S, Hamlin S, Scheffler M. Statistical trends of episiotomy around the world: comparative systematic review of changing practices. Health Care Women Int. 2018;39(6):644\u201362. https:\/\/doi.org\/10.1080\/07399332.2018.1445253","journal-title":"Health Care Women Int"},{"issue":"7","key":"6911_CR2","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1016\/j.jogoh.2018.12.002","volume":"48","author":"G Ducarme","year":"2019","unstructured":"Ducarme G, Pizzoferrato AC, de Tayrac R, Schantz C, Thubert T, Le Ray C, et al. Perineal prevention and protection in obstetrics: CNGOF clinical practice guidelines. J Gynecol Obstet Hum Reprod. 2019;48(7):455\u201360. https:\/\/doi.org\/10.1016\/j.jogoh.2018.12.002","journal-title":"J Gynecol Obstet Hum Reprod"},{"key":"6911_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.ejogrb.2019.05.038","volume":"240","author":"K Jones","year":"2019","unstructured":"Jones K, Webb S, Manresa M, Hodgetts-Morton V, Morris RK. The incidence of wound infection and dehiscence following childbirth-related perineal trauma: a systematic review of the evidence. Eur J Obstet Gynecol Reprod Biol. 2019;240:1\u20138. https:\/\/doi.org\/10.1016\/j.ejogrb.2019.05.038","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"3","key":"6911_CR4","doi-asserted-by":"publisher","first-page":"215","DOI":"10.3109\/01443615.2013.866080","volume":"34","author":"A Kamel","year":"2014","unstructured":"Kamel A, Khaled M. Episiotomy and obstetric perineal wound dehiscence: beyond soreness. J Obstet Gynaecol. 2014;34(3):215\u20137. https:\/\/doi.org\/10.3109\/01443615.2013.866080","journal-title":"J Obstet Gynaecol"},{"issue":"2","key":"6911_CR5","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1016\/j.ajog.2022.05.012","volume":"227","author":"NA Okeahialam","year":"2022","unstructured":"Okeahialam NA, Wong KW, Thakar R, Sultan AH. The incidence of wound complications following primary repair of obstetric anal sphincter injury: a systematic review and meta-analysis. Am J Obstet Gynecol. 2022;227(2):182\u201391. https:\/\/doi.org\/10.1016\/j.ajog.2022.05.012","journal-title":"Am J Obstet Gynecol"},{"issue":"7","key":"6911_CR6","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1089\/wound.2012.0383","volume":"2","author":"TA Wilgus","year":"2013","unstructured":"Wilgus TA, Roy S, McDaniel JC. Neutrophils and wound repair: positive actions and negative reactions. Adv Wound Care (New Rochelle). 2013;2(7):379\u201388. https:\/\/doi.org\/10.1089\/wound.2012.0383","journal-title":"Adv Wound Care (New Rochelle)"},{"issue":"3","key":"6911_CR7","doi-asserted-by":"publisher","first-page":"694","DOI":"10.3390\/biomedicines13030694","volume":"13","author":"F Reno","year":"2025","unstructured":"Reno F, Pagano CA, Bignotto M, Sabbatini M. Neutrophil heterogeneity in wound healing. Biomedicines. 2025;13(3):694. https:\/\/doi.org\/10.3390\/biomedicines13030694","journal-title":"Biomedicines"},{"issue":"7","key":"6911_CR8","doi-asserted-by":"publisher","first-page":"2629","DOI":"10.1172\/JCI124616","volume":"129","author":"M Peiseler","year":"2019","unstructured":"Peiseler M, Kubes P. More friend than foe: the emerging role of neutrophils in tissue repair. J Clin Invest. 2019;129(7):2629\u201339. https:\/\/doi.org\/10.1172\/JCI124616","journal-title":"J Clin Invest"},{"issue":"3","key":"6911_CR9","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1007\/s00441-017-2785-7","volume":"371","author":"J Wang","year":"2018","unstructured":"Wang J. Neutrophils in tissue injury and repair. Cell Tissue Res. 2018;371(3):531\u20139. https:\/\/doi.org\/10.1007\/s00441-017-2785-7","journal-title":"Cell Tissue Res"},{"issue":"1","key":"6911_CR10","first-page":"5","volume":"102","author":"R Zahorec","year":"2001","unstructured":"Zahorec R. Ratio of neutrophil to lymphocyte counts\u2013rapid and simple parameter of systemic inflammation and stress in critically ill. Bratisl Lek Listy. 2001;102(1):5\u201314.","journal-title":"Bratisl Lek Listy"},{"issue":"23","key":"6911_CR11","doi-asserted-by":"publisher","first-page":"6212","DOI":"10.1158\/1078-0432.CCR-14-0442","volume":"20","author":"B Hu","year":"2014","unstructured":"Hu B, Yang XR, Xu Y, Sun YF, Sun C, Guo W, et al. Systemic immune-inflammation index predicts prognosis of patients after curative resection for hepatocellular carcinoma. Clin Cancer Res. 2014;20(23):6212\u201322. https:\/\/doi.org\/10.1158\/1078-0432.CCR-14-0442","journal-title":"Clin Cancer Res"},{"issue":"5","key":"6911_CR12","doi-asserted-by":"publisher","first-page":"e15586","DOI":"10.1016\/j.heliyon.2023.e15586","volume":"9","author":"B Qian","year":"2023","unstructured":"Qian B, Zheng Y, Jia H, Zheng X, Gao R, Li W. Neutrophil-lymphocyte ratio as a predictive marker for postoperative infectious complications: a systematic review and meta-analysis. Heliyon. 2023;9(5):e15586. https:\/\/doi.org\/10.1016\/j.heliyon.2023.e15586","journal-title":"Heliyon"},{"issue":"1","key":"6911_CR13","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1080\/00016489.2016.1218047","volume":"137","author":"Y Maruyama","year":"2017","unstructured":"Maruyama Y, Inoue K, Mori K, Gorai K, Shimamoto R, Onitsuka T, et al. Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio as predictors of wound healing failure in head and neck reconstruction. Acta Otolaryngol. 2017;137(1):106\u201310. https:\/\/doi.org\/10.1080\/00016489.2016.1218047","journal-title":"Acta Otolaryngol"},{"key":"6911_CR14","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1016\/j.ejogrb.2019.12.009","volume":"245","author":"R Rotem","year":"2020","unstructured":"Rotem R, Erenberg M, Rottenstreich M, Segal D, Yohay Z, Idan I, et al. Early prediction of post cesarean section infection using simple hematological biomarkers: a case control study. Eur J Obstet Gynecol Reprod Biol. 2020;245:84\u20138. https:\/\/doi.org\/10.1016\/j.ejogrb.2019.12.009","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"8","key":"6911_CR15","doi-asserted-by":"publisher","first-page":"39050","DOI":"10.31083\/ceog39050","volume":"52","author":"I Temur","year":"2025","unstructured":"Temur I. Early prediction of post-cesarean infection using preoperative and postoperative hematologic markers: a case-control study. Clin Exp Obstet Gynecol. 2025;52(8):39050. https:\/\/doi.org\/10.31083\/ceog39050","journal-title":"Clin Exp Obstet Gynecol"},{"key":"6911_CR16","doi-asserted-by":"publisher","first-page":"103715","DOI":"10.1016\/j.ebiom.2021.103715","volume":"74","author":"S Dockree","year":"2021","unstructured":"Dockree S, Shine B, Pavord S, Impey L, Vatish M. White blood cells in pregnancy: reference intervals for before and after delivery. EBioMedicine. 2021;74:103715. https:\/\/doi.org\/10.1016\/j.ebiom.2021.103715","journal-title":"EBioMedicine"},{"issue":"4","key":"6911_CR17","doi-asserted-by":"publisher","first-page":"1746","DOI":"10.4049\/jimmunol.1201213","volume":"190","author":"AL Brubaker","year":"2013","unstructured":"Brubaker AL, Rendon JL, Ramirez L, Choudhry MA, Kovacs EJ. Reduced neutrophil chemotaxis and infiltration contributes to delayed resolution of cutaneous wound infection with advanced age. J Immunol. 2013;190(4):1746\u201357. https:\/\/doi.org\/10.4049\/jimmunol.1201213","journal-title":"J Immunol"},{"issue":"4","key":"6911_CR18","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1189\/jlb.0802406","volume":"73","author":"JV Dovi","year":"2003","unstructured":"Dovi JV, He LK, DiPietro LA. Accelerated wound closure in neutrophil-depleted mice. J Leukoc Biol. 2003;73(4):448\u201355. https:\/\/doi.org\/10.1189\/jlb.0802406","journal-title":"J Leukoc Biol"},{"issue":"3","key":"6911_CR19","doi-asserted-by":"publisher","first-page":"1121","DOI":"10.17826\/cumj.1123893","volume":"47","author":"D Tu\u011frul Ersak","year":"2022","unstructured":"Tu\u011frul Ersak D, Ersak B, Zorlu U, Kokanali MK, Moralo\u011flu Tekin \u00d6, Do\u011fanay M. A model to predict the risk of infected episiotomy in low-risk women. Cukurova Med J. 2022;47(3):1121\u20138. https:\/\/doi.org\/10.17826\/cumj.1123893","journal-title":"Cukurova Med J"},{"issue":"8","key":"6911_CR20","doi-asserted-by":"publisher","first-page":"3036","DOI":"10.3390\/jcm12083036","volume":"12","author":"A Puissegur","year":"2023","unstructured":"Puissegur A, Accoceberry M, Rouzaire M, Pereira B, Herault M, Bruhat C, et al. Risk factors for perineal wound breakdown in early postpartum: a retrospective case-control study. J Clin Med. 2023;12(8):3036. https:\/\/doi.org\/10.3390\/jcm12083036","journal-title":"J Clin Med"},{"issue":"3","key":"6911_CR21","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/j.ajog.2006.06.085","volume":"195","author":"MK Williams","year":"2006","unstructured":"Williams MK, Chames MC. Risk factors for the breakdown of perineal laceration repair after vaginal delivery. Am J Obstet Gynecol. 2006;195(3):755\u20139. https:\/\/doi.org\/10.1016\/j.ajog.2006.06.085","journal-title":"Am J Obstet Gynecol"},{"issue":"1","key":"6911_CR22","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/s00404-019-05165-1","volume":"300","author":"D Gommesen","year":"2019","unstructured":"Gommesen D, Nohr EA, Drue HC, Qvist N, Rasch V. Obstetric perineal tears: risk factors, wound infection and dehiscence: a prospective cohort study. Arch Gynecol Obstet. 2019;300(1):67\u201377. https:\/\/doi.org\/10.1007\/s00404-019-05165-1","journal-title":"Arch Gynecol Obstet"},{"issue":"11","key":"6911_CR23","doi-asserted-by":"publisher","first-page":"CD012136","DOI":"10.1002\/14651858.CD012136.pub2","volume":"11","author":"M Bonet","year":"2017","unstructured":"Bonet M, Ota E, Chibueze CE, Oladapo OT. Antibiotic prophylaxis for episiotomy repair following vaginal birth. Cochrane Database Syst Rev. 2017;11(11):CD012136. https:\/\/doi.org\/10.1002\/14651858.CD012136.pub2","journal-title":"Cochrane Database Syst Rev"},{"issue":"Suppl 1","key":"6911_CR24","doi-asserted-by":"publisher","first-page":"21S","DOI":"10.1097\/PRS.0b013e3181fbe291","volume":"127","author":"G Hahm","year":"2011","unstructured":"Hahm G, Glaser JJ, Elster EA. Biomarkers to predict wound healing: the future of complex war wound management. Plast Reconstr Surg. 2011;127(Suppl 1):21S\u201326S. https:\/\/doi.org\/10.1097\/PRS.0b013e3181fbe291","journal-title":"Plast Reconstr Surg"}],"container-title":["International Urogynecology Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-026-06911-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00192-026-06911-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00192-026-06911-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T11:51:35Z","timestamp":1789991495000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00192-026-06911-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,21]]},"references-count":24,"alternative-id":["6911"],"URL":"https:\/\/doi.org\/10.1007\/s00192-026-06911-1","relation":{},"ISSN":["0937-3462","1433-3023"],"issn-type":[{"value":"0937-3462","type":"print"},{"value":"1433-3023","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,21]]},"assertion":[{"value":"6 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by the Scientific Research Ethics Committee No. 1 of Ba\u015fak\u015fehir \u00c7am and Sakura City Hospital (decision number 258, dated 27 August 2025; reference KAEK\/27.08.2025.258). Because of the retrospective design, the requirement for informed consent was waived.","order":1,"name":"Ethics","label":"Ethics Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}