{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T06:52:43Z","timestamp":1761807163169},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2005,6,28]],"date-time":"2005-06-28T00:00:00Z","timestamp":1119916800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1007\/s00198-005-1858-8","type":"journal-article","created":{"date-parts":[[2005,6,27]],"date-time":"2005-06-27T16:39:55Z","timestamp":1119890395000},"page":"2180-2184","source":"Crossref","is-referenced-by-count":27,"title":["Hepatitis C-associated osteosclerosis (HCAO): report of a new case with involvement of the OPG\/RANKL system"],"prefix":"10.1007","volume":"16","author":[{"given":"C. E.","family":"Fiore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Riccobene","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mangiafico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Santoro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Pennisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,6,28]]},"reference":[{"key":"1858_CR1","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1093\/oxfordjournals.bmb.a072408","volume":"46","author":"Choo","year":"1990","unstructured":"Choo QL, Weiner AJ, Overby LR (1990) Hepatitis C virus: the major causative agent of viral non-A, non-B hepatitis. Br Med Bull 46:423-441","journal-title":"Br Med Bull"},{"key":"1858_CR2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0002-9343(92)90165-8","volume":"93","author":"Villareal","year":"1992","unstructured":"Villareal DT, Murphy WA, Teitelbaum SL, Arens MQ, Whyte MP (1992) Painful diffuse osteosclerosis after intravenous drug abuse. Am J Med 93:371\u2013381","journal-title":"Am J Med"},{"key":"1858_CR3","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/0002-9343(93)90364-U","volume":"95","author":"Beyer","year":"1993","unstructured":"Beyer HS, Anderson Q, Shih MS, Parfitt AM, Heath H (1993) Diffuse osteosclerosis in intravenous drug abusers. Am J Med 95:660\u2013661","journal-title":"Am J Med"},{"key":"1858_CR4","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/jbmr.5650110417","volume":"11","author":"Whyte","year":"1996","unstructured":"Whyte MP, Teitelbaum SL, Reinus WR (1996) Doubling skeletal mass during adult life: the syndrome of diffuse osteosclerosis after intravenous drug abuse. J Bone Miner Res 11:554\u2013558","journal-title":"J Bone Miner Res"},{"key":"1858_CR5","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/S8756-3282(96)00304-3","volume":"19","author":"Diamond","year":"1996","unstructured":"Diamond T, Depczysnki B (1996) Acquired osteosclerosis associated with intravenous drug use and hepatitis C infection. Bone 19:679\u2013683","journal-title":"Bone"},{"key":"1858_CR6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0002-9343(97)89507-1","volume":"102","author":"Whyte","year":"1997","unstructured":"Whyte MP, Reasner CA (1997) Hepatitis C-associated osteosclerosis after blood transfusion. Am J Med 102:219\u2013229","journal-title":"Am J Med"},{"key":"1858_CR7","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0002-9343(97)00139-3","volume":"103","author":"Hassoun","year":"1997","unstructured":"Hassoun AAK, Nippoldt TB, Tiegs RD, Khosla S (1997) Hepatitis C-associated osteosclerosis: an unusual syndrome of acquired osteosclerosis in adults. Am J Med 103:70\u201373","journal-title":"Am J Med"},{"key":"1858_CR8","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1210\/jcem.83.1.4521","volume":"83","author":"Shaker","year":"1998","unstructured":"Shaker JL, Reims WR, Whyte MP (1998) Hepatitis C-associated osteosclerosis: late onset after blood transfusion in an elderly woman. J Clin Endocrinol Metab 83:93\u201398","journal-title":"J Clin Endocrinol Metab"},{"key":"1858_CR9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1002\/art.10770","volume":"48","author":"Wakitani","year":"2003","unstructured":"Wakitani S, Hattori T, Nakaya H, Chae YM, Murata N, Tanigami A (2003) Clinical images: hepatitis C-associated osteosclerosis. Arthritis Rheum 48:268","journal-title":"Arthritis Rheum"},{"key":"1858_CR10","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1172\/JCI1111","volume":"101","author":"Khosla","year":"1998","unstructured":"Khosla S, Hassoun AAK, Baker BK, Liu F, Zein NN, Whyte MP, Reasner CA, Nippoldt TB, Tiegs RD, Hintz RL (1998) Insulin-like growth factor system abnormalities in hepatitis C-associated osteosclerosis. J Clin Invest 101:2165\u20132173","journal-title":"J Clin Invest"},{"key":"1858_CR11","doi-asserted-by":"crossref","first-page":"3867","DOI":"10.1210\/jcem.87.8.8783","volume":"87","author":"Khosla","year":"2002","unstructured":"Khosla S, Ballard FJ, Conover CA (2002) Use of site-specific antibodies to characterize the circulating form of big insulin-like growth factor II in patients with hepatitis C-associated osteosclerosis. J Clin Endocrinol Metab 87:3867\u20133870","journal-title":"J Clin Endocrinol Metab"},{"key":"1858_CR12","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.1210\/endo.142.12.8536","volume":"142","author":"Khosla","year":"2001","unstructured":"Khosla S (2001) Minireview: the OPG\/RANK\/RANKL system. Endocrinology 142:5050\u20135055","journal-title":"Endocrinology"},{"key":"1858_CR13","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1210\/jcem.84.1.5427-7","volume":"84","author":"Shaker","year":"1999","unstructured":"Shaker JL, Moore BP, Whyte MP (1999) Hyperparathyroidism and increased serum IGF-binding protein-2 levels in hepatitis C-associated osteosclerosis. J Clin Endocrinol Metab 84:384\u2013385","journal-title":"J Clin Endocrinol Metab"},{"key":"1858_CR14","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1002\/jbmr.5650111010","volume":"11","author":"Whyte","year":"1996","unstructured":"Whyte MP, Chines A, Silva DP, Landt Y, Ladenson JH (1996) Creatine kinase brain isoenzyme (BB-CK) presence in serum distinguishes osteopetroses among the sclerosing bone disorders. J Bone Miner Res 11:1438\u20131443","journal-title":"J Bone Miner Res"},{"key":"1858_CR15","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/s00198-003-1550-9","volume":"15","author":"Pennisi","year":"2004","unstructured":"Pennisi P, Signorelli SS, Riccobene S, Celotta G, Di Pino L, La Malfa T, Fiore CE (2004) Low bone density and abnormal bone turnover in patients with atherosclerosis of peripheral vessels. Osteoporos Int 15:389\u2013395","journal-title":"Osteoporos Int"},{"key":"1858_CR16","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0168-8278(02)00435-X","volume":"38","author":"Szalay","year":"2003","unstructured":"Szalay F, Hegedus D, Lakatos PL, Tornai I, Bajnock E, Dunkel K, Lakatos P (2003) High serum osteoprotegerin and low RANKL in primary biliary cirrhosis. J Hepatol 38:395\u2013400","journal-title":"J Hepatol"},{"key":"1858_CR17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1083\/jcb.145.3.527","volume":"145","author":"Burgess","year":"1999","unstructured":"Burgess TL, Qian YX, Kaufman S, Ring BD, Van G, Capparelli C (1999) The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol 145:527\u2013538","journal-title":"J Cell Biol"},{"key":"1858_CR18","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1359\/JBMR.040305","volume":"19","author":"Bekker","year":"2004","unstructured":"Bekker PJ, Holloway DL, Rasmussen AS, Murphy R, Martin SW, Leese PT, Holmes GB, Dunstan CR, DePaoli AM (2004) A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women. J Bone Miner Res 19:1059\u20131066","journal-title":"J Bone Miner Res"},{"key":"1858_CR19","first-page":"148","volume":"29","author":"Tappero","year":"1997","unstructured":"Tappero G, Farina M, Negro F, Anfossi G, Mattiello L, Giuli PD, Colombatto P, Brunetto MR, Angeli A, Bonino F (1997) Intrahepatic expression of c-fos, c-myb and c-myc oncogenes: correlation with virus-induced chronic liver disease and response to interferon. Ital J Gastroenterol Hepatol 29:148\u2013154","journal-title":"Ital J Gastroenterol Hepatol"},{"key":"1858_CR20","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/79683","volume":"6","author":"Sabatakos","year":"2000","unstructured":"Sabatakos G, Sims NA, Chen K, Aoki K, Kelz MB, Amling M, Bouali V, Mukhopadhyay K, Ford K, Nestler EJ, Baron R (2000) Overexpression of \u0394Fos B transcription factor(s) increases bone formation and inhibits adipogenesis. Nat Med 6:985\u2013990","journal-title":"Nat Med"},{"key":"1858_CR21","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1038\/79676","volume":"6","author":"Jochum","year":"2000","unstructured":"Jochum W, David JP, Elliot C, Wutz A, Plenk H, Matsuo K, Wagner EF (2000) Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1. Nat Med 6:980\u2013984","journal-title":"Nat Med"},{"key":"1858_CR22","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/72855","volume":"24","author":"Matsuo","year":"2000","unstructured":"Matsuo K, Owens JM, Tonko M, Elliot C, Chambers TJ, Wagner EF (2000) Fos-1 is a transcriptional target of c-Fos during osteoclast differentiation. Nat Genet 24:184\u2013187","journal-title":"Nat Genet"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-005-1858-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-005-1858-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-005-1858-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T15:03:55Z","timestamp":1558623835000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-005-1858-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6,28]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["1858"],"URL":"https:\/\/doi.org\/10.1007\/s00198-005-1858-8","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,6,28]]}}}