{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T01:43:56Z","timestamp":1789868636881,"version":"4.0.1"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2005,3,3]],"date-time":"2005-03-03T00:00:00Z","timestamp":1109808000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1007\/s00198-005-1860-1","type":"journal-article","created":{"date-parts":[[2005,3,2]],"date-time":"2005-03-02T15:38:50Z","timestamp":1109777930000},"page":"1425-1431","source":"Crossref","is-referenced-by-count":310,"title":["Association between 25-hydroxy vitamin D levels, physical activity, muscle strength and fractures in the prospective population-based OPRA Study of Elderly Women"],"prefix":"10.1007","volume":"16","author":[{"given":"P.","family":"Gerdhem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. A. M.","family":"Ringsberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. J.","family":"Obrant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Akesson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2005,3,3]]},"reference":[{"key":"1860_CR1","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.1016\/S0140-6736(02)08761-5","volume":"359","author":"Kanis","year":"2002","unstructured":"Kanis JA (2002) Diagnosis of osteoporosis and assessment of fracture risk. Lancet 359:1929\u20131936","journal-title":"Lancet"},{"key":"1860_CR2","doi-asserted-by":"crossref","unstructured":"Gillespie LD, Gillespie WJ, Robertson MC, Lamb SE, Cumming RG, Rowe BH (2002) Interventions for preventing falls in elderly people (Cochrane Review). Cochrane Library, www.cochrane.org","DOI":"10.1002\/14651858.CD000340"},{"key":"1860_CR3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1097\/00060793-200202000-00011","volume":"Diabetes","author":"Holick","year":"2002","unstructured":"Holick MF (2002) Vitamin D: the underappreciated D-lightful hormone that is important for skeletal and cellular health. Curr Opin Endocrinol Diabetes:87\u201398","journal-title":"Curr Opin Endocrinol"},{"key":"1860_CR4","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1210\/edrv.22.4.0437","volume":"22","author":"Lips","year":"2001","unstructured":"Lips P (2001) Vitamin D deficiency and secondary hyperparathyroidism in the elderly: consequences for bone loss and fractures and therapeutic implications. Endocr Rev 22:477\u2013501","journal-title":"Endocr Rev"},{"key":"1860_CR5","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s001980200012","volume":"13","author":"Pfeifer","year":"2002","unstructured":"Pfeifer M, Begerow B, Minne HW (2002) Vitamin D and muscle function. Osteoporos Int 13:187\u2013194","journal-title":"Osteoporos Int"},{"key":"1860_CR6","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0003-9993(99)90307-6","volume":"80","author":"Bischoff","year":"1999","unstructured":"Bischoff HA, Stahelin HB, Urscheler N, Ehrsam R, Vonthein R, Perrig-Chiello P, Tyndall A, Theiler R (1999) Muscle strength in the elderly: its relation to vitamin D metabolites. Arch Phys Med Rehabil 80:54\u201358","journal-title":"Arch Phys Med Rehabil"},{"key":"1860_CR7","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1532-5415.1999.tb04581.x","volume":"47","author":"Mowe","year":"1999","unstructured":"Mowe M, Haug E, Bohmer T (1999) Low serum calcidiol concentration in older adults with reduced muscular function. J Am Geriatr Soc 47:220\u2013226","journal-title":"J Am Geriatr Soc"},{"key":"1860_CR8","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/S0140-6736(76)90428-1","volume":"1","author":"Schott","year":"1976","unstructured":"Schott GD, Wills MR (1976) Muscle weakness in osteomalacia. Lancet 1:626\u2013629","journal-title":"Lancet"},{"key":"1860_CR9","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s002230010085","volume":"66","author":"Glerup","year":"2000","unstructured":"Glerup H, Mikkelsen K, Poulsen L, Hass E, Overbeck S, Andersen H, Charles P, Eriksen EF (2000) Hypovitaminosis D myopathy without biochemical signs of osteomalacic bone involvement. Calcif Tissue Int 66:419\u2013424","journal-title":"Calcif Tissue Int"},{"key":"1860_CR10","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1359\/jbmr.2000.15.6.1113","volume":"15","author":"Pfeifer","year":"2000","unstructured":"Pfeifer M, Begerow B, Minne HW, Abrams C, Nachtigall D, Hansen C (2000) Effects of a short-term vitamin D and calcium supplementation on body sway and secondary hyperparathyroidism in elderly women. J Bone Miner Res 15:1113\u20131118","journal-title":"J Bone Miner Res"},{"key":"1860_CR11","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1359\/jbmr.2002.17.5.891","volume":"17","author":"Dhesi","year":"2002","unstructured":"Dhesi JK, Bearne LM, Moniz C, Hurley MV, Jackson SH, Swift CG, Allain TJ (2002) Neuromuscular and psychomotor function in elderly subjects who fall and the relationship with vitamin D status. J Bone Miner Res 17:891\u2013897","journal-title":"J Bone Miner Res"},{"key":"1860_CR12","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1359\/jbmr.2003.18.2.343","volume":"18","author":"Bischoff","year":"2003","unstructured":"Bischoff HA, Stahelin HB, Dick W, Akos R, Knecht M, Salis C, Nebiker M, Theiler R, Pfeifer M, Begerow B, Lew RA, Conzelmann M (2003) Effects of vitamin D and calcium supplementation on falls: a randomized controlled trial. J Bone Miner Res 18:343\u2013351","journal-title":"J Bone Miner Res"},{"key":"1860_CR13","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1111\/j.1532-5415.1999.tb05199.x","volume":"47","author":"Stein","year":"1999","unstructured":"Stein MS, Wark JD, Scherer SC, Walton SL, Chick P, Di Carlantonio M, Zajac JD, Flicker L (1999) Falls relate to vitamin D and parathyroid hormone in an Australian nursing home and hostel. J Am Geriatr Soc 47:1195\u20131201","journal-title":"J Am Geriatr Soc"},{"key":"1860_CR14","first-page":"CD000227","volume":"Rev","author":"Gillespie","year":"2001","unstructured":"Gillespie WJ, Avenell A, Henry DA, O\u2019Connell DL, Robertson J (2001) Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis. Cochrane Database Syst Rev:CD000227","journal-title":"Cochrane Database Syst"},{"key":"1860_CR15","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1001\/jama.291.16.1999","volume":"291","author":"Bischoff-Ferrari","year":"2004","unstructured":"Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Staehelin HB, Bazemore MG, Zee RY, Wong JB (2004) Effect of Vitamin D on falls: a meta-analysis. JAMA 291:1999\u20132006","journal-title":"JAMA"},{"key":"1860_CR16","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0002-9343(92)90682-2","volume":"93","author":"McKenna","year":"1992","unstructured":"McKenna MJ (1992) Differences in vitamin D status between countries in young adults and the elderly. Am J Med 93:69\u201377","journal-title":"Am J Med"},{"key":"1860_CR17","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1056\/NEJM199809103391104","volume":"339","author":"Cummings","year":"1998","unstructured":"Cummings SR, Browner WS, Bauer D, Stone K, Ensrud K, Jamal S, Ettinger B (1998) Endogenous hormones and the risk of hip and vertebral fractures among older women. Study of Osteoporotic Fractures Research Group. N Engl J Med 339:733\u2013738","journal-title":"N Engl J Med"},{"key":"1860_CR18","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1159\/000069169","volume":"49","author":"Gerdhem","year":"2003","unstructured":"Gerdhem P, Ringsberg KA, Magnusson H, Obrant KJ, Akesson K (2003) Bone mass cannot be predicted by estimations of frailty in elderly ambulatory women. Gerontology 49:168\u2013172","journal-title":"Gerontology"},{"key":"1860_CR19","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/ageing\/28.3.289","volume":"28","author":"Ringsberg","year":"1999","unstructured":"Ringsberg K, Gerdhem P, Johansson J, Obrant KJ (1999) Is there a relationship between balance, gait performance and muscular strength in 75-year-old women? Age Ageing 28:289\u2013293","journal-title":"Age Ageing"},{"key":"1860_CR20","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1007\/s00198-002-1362-3","volume":"14","author":"Gerdhem","year":"2003","unstructured":"Gerdhem P, Akesson K, Obrant KJ (2003) Effect of previous and present physical activity on bone mass in elderly women. Osteoporos Int 14:208\u2013212","journal-title":"Osteoporos Int"},{"key":"1860_CR21","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/S0140-6736(05)78933-9","volume":"351","author":"Malabanan","year":"1998","unstructured":"Malabanan A, Veronikis IE, Holick MF (1998) Redefining vitamin D insufficiency. Lancet 351:805\u2013806","journal-title":"Lancet"},{"key":"1860_CR22","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s001980050030","volume":"7","author":"Chapuy","year":"1997","unstructured":"Chapuy MC, Preziosi P, Maamer M, Arnaud S, Galan P, Hercberg S, Meunier PJ (1997) Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 7:439\u2013443","journal-title":"Osteoporos Int"},{"key":"1860_CR23","doi-asserted-by":"crossref","unstructured":"Melin AL, Wilske J, Ringertz H, Saaf M (1999) Vitamin D status, parathyroid function and femoral bone density in an elderly Swedish population living at home. Aging (Milano) 11:200\u2013207","DOI":"10.1007\/BF03399663"},{"key":"1860_CR24","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1159\/000067948","volume":"49","author":"Moreland","year":"2003","unstructured":"Moreland J, Richardson J, Chan DH, O\u2019Neill J, Bellissimo A, Grum RM, Shanks L (2003) Evidence-based guidelines for the secondary prevention of falls in older adults. Gerontology 49:93\u2013116","journal-title":"Gerontology"},{"key":"1860_CR25","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1056\/NEJM199503233321202","volume":"332","author":"Cummings","year":"1995","unstructured":"Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM (1995) Risk factors for hip fracture in white women. Study of Osteoporotic Fractures Research Group. N Engl J Med 332:767\u2013773","journal-title":"N Engl J Med"},{"key":"1860_CR26","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1210\/jcem-66-5-927","volume":"66","author":"Nelson","year":"1988","unstructured":"Nelson ME, Meredith CN, Dawson-Hughes B, Evans WJ (1988) Hormone and bone mineral status in endurance-trained and sedentary postmenopausal women. J Clin Endocrinol Metab 66:927\u2013933","journal-title":"J Clin Endocrinol Metab"},{"key":"1860_CR27","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/jbmr.5650030402","volume":"3","author":"Bell","year":"1988","unstructured":"Bell NH, Godsen RN, Henry DP, Shary J, Epstein S (1988) The effects of muscle-building exercise on vitamin D and mineral metabolism. J Bone Miner Res 3:369\u2013373","journal-title":"J Bone Miner Res"},{"key":"1860_CR28","first-page":"S52","volume":"18","author":"Bischoff","year":"2003","unstructured":"Bischoff HA, Dietrich T, Orav EJ, Zhang Y, W. KE, Dawson-Hughes B (2003) Higher 25-hydroxyvitamin D levels are associated with better lower extremity function in active and inactive ambulatory elderly in the US (abstract). J Bone Miner Res 18:S52","journal-title":"J Bone Miner Res"},{"key":"1860_CR29","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1007\/s00198-002-1338-3","volume":"14","author":"Bates","year":"2003","unstructured":"Bates CJ, Carter GD, Mishra GD, O\u2019Shea D, Jones J, Prentice A (2003) In a population study, can parathyroid hormone aid the definition of adequate vitamin D status? A study of people aged 65\u00a0years and over from the British National Diet and Nutrition Survey. Osteoporos Int 14:152\u2013159","journal-title":"Osteoporos Int"},{"key":"1860_CR30","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1111\/j.1532-5415.1995.tb07404.x","volume":"43","author":"Gloth","year":"1995","unstructured":"Gloth FM, 3rd, Smith CE, Hollis BW, Tobin JD (1995) Functional improvement with vitamin D replenishment in a cohort of frail, vitamin D-deficient older people. J Am Geriatr Soc 43:1269\u20131271","journal-title":"J Am Geriatr Soc"},{"key":"1860_CR31","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1093\/ageing\/14.2.76","volume":"14","author":"Corless","year":"1985","unstructured":"Corless D, Dawson E, Fraser F, Ellis M, Evans SJ, Perry JD, Reisner C, Silver CP, Beer M, Boucher BJ (1985) Do vitamin D supplements improve the physical capabilities of elderly hospital patients? Age Ageing 14:76\u201384","journal-title":"Age Ageing"},{"key":"1860_CR32","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF01774013","volume":"5","author":"Meyer","year":"1995","unstructured":"Meyer HE, Henriksen C, Falch JA, Pedersen JI, Tverdal A (1995) Risk factors for hip fracture in a high incidence area: a case-control study from Oslo, Norway. Osteoporos Int 5:239\u2013246","journal-title":"Osteoporos Int"},{"key":"1860_CR33","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/ajcn\/77.2.504","volume":"77","author":"Feskanich","year":"2003","unstructured":"Feskanich D, Willett WC, Colditz GA (2003) Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women. Am J Clin Nutr 77:504\u2013511","journal-title":"Am J Clin Nutr"},{"key":"1860_CR34","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1136\/bmj.326.7387.469","volume":"326","author":"Trivedi","year":"2003","unstructured":"Trivedi DP, Doll R, Khaw KT (2003) Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. BMJ 326:469","journal-title":"BMJ"},{"key":"1860_CR35","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1056\/NEJM199709043371003","volume":"337","author":"Dawson-Hughes","year":"1997","unstructured":"Dawson-Hughes B, Harris SS, Krall EA, Dallal GE (1997) Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337:670\u2013676","journal-title":"N Engl J Med"},{"key":"1860_CR36","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/s001980050162","volume":"9","author":"Lips","year":"1999","unstructured":"Lips P, Chapuy MC, Dawson-Hughes B, Pols HA, Holick MF (1999) An international comparison of serum 25-hydroxyvitamin D measurements. Osteoporos Int 9:394\u2013397","journal-title":"Osteoporos Int"},{"key":"1860_CR37","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1210\/jc.2003-031979","volume":"89","author":"Binkley","year":"2004","unstructured":"Binkley N, Krueger D, Cowgill CS, Plum L, Lake E, Hansen KE, DeLuca HF, Drezner MK (2004) Assay variation confounds the diagnosis of hypovitaminosis D: a call for standardization. J Clin Endocrinol Metab 89:3152\u20133157","journal-title":"J Clin Endocrinol Metab"},{"key":"1860_CR38","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1210\/jc.2004-0682","volume":"89","author":"Hollis","year":"2004","unstructured":"Hollis BW (2004) Editorial: the determination of circulating 25-hydroxyvitamin D: no easy task. J Clin Endocrinol Metab 89:3149\u20133151","journal-title":"J Clin Endocrinol Metab"},{"key":"1860_CR39","first-page":"357","volume":"47","author":"Roth","year":"2001","unstructured":"Roth HJ, Zahn I, Alkier R, Schmidt H (2001) Validation of the first automated chemiluminescence protein-binding assay for the detection of 25-hydroxycalciferol. Clin Lab 47:357\u2013365","journal-title":"Clin Lab"},{"key":"1860_CR40","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1080\/07315724.2003.10719287","volume":"22","author":"Heaney","year":"2003","unstructured":"Heaney RP, Dowell MS, Hale CA, Bendich A (2003) Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr 22:142\u2013146","journal-title":"J Am Coll Nutr"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-005-1860-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-005-1860-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-005-1860-1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,6]],"date-time":"2020-04-06T02:24:26Z","timestamp":1586139866000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-005-1860-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3,3]]},"references-count":40,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005,11]]}},"alternative-id":["1860"],"URL":"https:\/\/doi.org\/10.1007\/s00198-005-1860-1","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3,3]]}}}