{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T14:11:12Z","timestamp":1771942272881,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2011,6,21]],"date-time":"2011-06-21T00:00:00Z","timestamp":1308614400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1007\/s00198-011-1664-4","type":"journal-article","created":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T12:05:12Z","timestamp":1308571512000},"page":"53-58","source":"Crossref","is-referenced-by-count":30,"title":["Predictors of new and severe vertebral fractures: results from the HORIZON Pivotal Fracture Trial"],"prefix":"10.1007","volume":"23","author":[{"given":"R.","family":"Wustrack","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Seeman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Bucci-Rechtweg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Burch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Palermo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. M.","family":"Black","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2011,6,21]]},"reference":[{"key":"1664_CR1","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1359\/jbmr.061113","volume":"22","author":"R Burge","year":"2007","unstructured":"Burge R, Dawson-Hughes B, Solomon D, Wong J, King A, Tosteson A (2007) Incidence and economic burden of osteoporosis-related fractures in the United States, 2005\u20132025. J Bone Miner Res 22:465\u2013475","journal-title":"J Bone Miner Res"},{"key":"1664_CR2","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00198-004-1702-6","volume":"16","author":"O Johnell","year":"2005","unstructured":"Johnell O, Kanis J (2005) Epidemiology of osteoporotic fractures. Osteoporos Int 16:3\u20137","journal-title":"Osteoporos Int"},{"key":"1664_CR3","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1007\/s00198-003-1463-7","volume":"15","author":"J Kanis","year":"2004","unstructured":"Kanis J, Johnell O, Oden A, Borgstrom F, Zethraeus N, Laet C, Jonsson B (2004) The risk and burden of vertebral fractures in Sweden. Osteoporos Int 15:20\u201326","journal-title":"Osteoporos Int"},{"key":"1664_CR4","doi-asserted-by":"crossref","first-page":"793","DOI":"10.7326\/0003-4819-128-10-199805150-00001","volume":"128","author":"M Nevitt","year":"1998","unstructured":"Nevitt M, Ettinger B, Black D, Stone K, Jamal S, Ensrud K, Segal M, Genant H, Cummings S (1998) The association of radiographically detected vertebral fractures with back pain and function: a prospective study. Ann Intern Med 128:793","journal-title":"Ann Intern Med"},{"key":"1664_CR5","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s00223-004-2222-2","volume":"76","author":"R Hasserius","year":"2005","unstructured":"Hasserius R, Karlsson M, Jonsson B, Redlund-Johnell I, Johnell O (2005) Long-term morbidity and mortality after a clinically diagnosed vertebral fracture in the elderly\u2014a 12- and 22-year follow-up of 257 patients. Calcif Tissue Int 76:235\u2013242","journal-title":"Calcif Tissue Int"},{"key":"1664_CR6","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1007\/s00198-005-2023-0","volume":"16","author":"J Fechtenbaum","year":"2005","unstructured":"Fechtenbaum J, Cropet C, Kolta S, Horlait S, Orcel P, Roux C (2005) The severity of vertebral fractures and health-related quality of life in osteoporotic postmenopausal women. Osteoporos Int 16:2175\u20132179","journal-title":"Osteoporos Int"},{"key":"1664_CR7","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1359\/jbmr.1999.14.5.821","volume":"14","author":"D Black","year":"1999","unstructured":"Black D, Arden N, Palermo L, Pearson J, Cummings S (1999) Prevalent vertebral deformities predict hip fractures and new vertebral deformities but not wrist fractures. J Bone Miner Res 14:821\u2013828","journal-title":"J Bone Miner Res"},{"key":"1664_CR8","doi-asserted-by":"crossref","first-page":"2761","DOI":"10.1001\/jama.298.23.2761","volume":"298","author":"J Cauley","year":"2007","unstructured":"Cauley J, Hochberg M, Lui L, Palermo L, Ensrud K, Hillier T, Nevitt M, Cummings S (2007) Long-term risk of incident vertebral fractures. Jama 298:2761","journal-title":"Jama"},{"key":"1664_CR9","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/S8756-3282(03)00241-2","volume":"33","author":"P Delmas","year":"2003","unstructured":"Delmas P, Genant H, Crans G, Stock J, Wong M, Siris E, Adachi J (2003) Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial. Bone 33:522\u2013532","journal-title":"Bone"},{"key":"1664_CR10","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00198-002-1316-9","volume":"14","author":"R Hasserius","year":"2003","unstructured":"Hasserius R, Karlsson M, Nilsson B, Johnell O (2003) Prevalent vertebral deformities predict increased mortality and increased fracture rate in both men and women: a 10-year population-based study of 598 individuals from the Swedish cohort in the European Vertebral Osteoporosis Study. Osteoporos Int 14:61\u201368","journal-title":"Osteoporos Int"},{"key":"1664_CR11","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.bone.2004.03.024","volume":"35","author":"J Kanis","year":"2004","unstructured":"Kanis J, Johnell O, De Laet C, Johansson H, Oden A, Delmas P, Eisman J, Fujiwara S, Garnero P, Kroger H (2004) A meta-analysis of previous fracture and subsequent fracture risk. Bone 35:375\u2013382","journal-title":"Bone"},{"key":"1664_CR12","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1001\/jama.285.3.320","volume":"285","author":"R Lindsay","year":"2001","unstructured":"Lindsay R, Silverman S, Cooper C, Hanley D, Barton I, Broy S, Licata A, Benhamou L, Geusens P, Flowers K (2001) Risk of new vertebral fracture in the year following a fracture. Jama 285:320","journal-title":"Jama"},{"key":"1664_CR13","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1007\/s00198-003-1405-4","volume":"14","author":"M Naves","year":"2003","unstructured":"Naves M, Diaz-Lopez J, Gomez C, Rodriguez-Rebollar A, Rodriguez-Garcia M, Cannata-Andia J (2003) The effect of vertebral fracture as a risk factor for osteoporotic fracture and mortality in a Spanish population. Osteoporos Int 14:520\u2013524","journal-title":"Osteoporos Int"},{"key":"1664_CR14","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/0140-6736(93)92555-8","volume":"341","author":"S Cummings","year":"1993","unstructured":"Cummings S, Browner W, Black D, Nevitt M, Genant H, Cauley J, Ensrud K, Scott J, Vogt T (1993) Bone density at various sites for prediction of hip fractures. Lancet 341:72\u201375","journal-title":"Lancet"},{"key":"1664_CR15","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1056\/NEJM199503233321202","volume":"332","author":"S Cummings","year":"1995","unstructured":"Cummings S, Nevitt M, Browner W, Stone K, Fox K, Ensrud K, Cauley J, Black D, Vogt T (1995) Risk factors for hip fracture in white women. N Engl J Med 332:767","journal-title":"N Engl J Med"},{"key":"1664_CR16","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1007\/s00198-007-0413-1","volume":"18","author":"C Roux","year":"2007","unstructured":"Roux C, Fechtenbaum J, Kolta S, Briot K, Girard M (2007) Mild prevalent and incident vertebral fractures are risk factors for new fractures. Osteoporos Int 18:1617\u20131624","journal-title":"Osteoporos Int"},{"key":"1664_CR17","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.bone.2005.04.003","volume":"37","author":"GG Crans","year":"2005","unstructured":"Crans GG, Genant HK, Krege JH (2005) Prognostic utility of a semiquantitative spinal deformity index. Bone 37:175\u2013179","journal-title":"Bone"},{"key":"1664_CR18","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1007\/s00198-008-0832-7","volume":"20","author":"S Kerkeni","year":"2009","unstructured":"Kerkeni S, Kolta S, Fechtenbaum J, Roux C (2009) Spinal deformity index (SDI) is a good predictor of incident vertebral fractures. Osteoporos Int 20:1547\u20131552","journal-title":"Osteoporos Int"},{"key":"1664_CR19","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S8756-3282(03)00248-5","volume":"33","author":"M Lunt","year":"2003","unstructured":"Lunt M, O\u2019Neill T, Felsenberg D, Reeve J, Kanis J, Cooper C, Silman A (2003) Characteristics of a prevalent vertebral deformity predict subsequent vertebral fracture: results from the European Prospective Osteoporosis Study (EPOS). Bone 33:505\u2013513","journal-title":"Bone"},{"key":"1664_CR20","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1056\/NEJMoa067312","volume":"356","author":"D Black","year":"2007","unstructured":"Black D, Delmas P, Eastell R, Reid I, Boonen S, Cauley J, Cosman F, Lakatos P, Leung P, Man Z (2007) Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med 356:1809","journal-title":"N Engl J Med"},{"key":"1664_CR21","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","volume":"8","author":"H Genant","year":"1993","unstructured":"Genant H, Wu C, Van Kuijk C, Nevitt M (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8:1137\u20131148","journal-title":"J Bone Miner Res"},{"key":"1664_CR22","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/jbmr.5650100610","volume":"10","author":"D Black","year":"1995","unstructured":"Black D, Palermo L, Nevitt M, Genant H, Epstein R, San Valentin R, Cummings S (1995) Comparison of methods for defining prevalent vertebral deformities: the Study of Osteoporotic Fractures. J Bone Mine Res 10:890\u2013902","journal-title":"J Bone Mine Res"},{"key":"1664_CR23","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1359\/jbmr.1999.14.1.90","volume":"14","author":"D Black","year":"1999","unstructured":"Black D, Palermo L, Nevitt M, Genant H, Christensen L, Cummings S (1999) Defining incident vertebral deformity: a prospective comparison of several approaches. J Bone Miner Res 14:90\u2013101","journal-title":"J Bone Miner Res"},{"key":"1664_CR24","first-page":"335","volume":"3","author":"H Minne","year":"1988","unstructured":"Minne H, Leidig G, W\u00fcster C, Siromachkostov L, Baldauf G, Bickel R, Sauer P, Lojen M, Ziegler R (1988) A newly developed spine deformity index (SDI) to quantitate vertebral crush fractures in patients with osteoporosis. Bone Miner 3:335","journal-title":"Bone Miner"},{"key":"1664_CR25","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1007\/s00198-006-0172-4","volume":"17","author":"O Johnell","year":"2006","unstructured":"Johnell O, Kanis J (2006) An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 17:1726\u20131733","journal-title":"Osteoporos Int"},{"key":"1664_CR26","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1359\/JBMR.040325","volume":"19","author":"C Chesnut III","year":"2004","unstructured":"Chesnut C III, Skag A, Christiansen C, Recker R, Stakkestad J, Hoiseth A, Felsenberg D, Huss H, Gilbride J, Schimmer R (2004) Effects of oral ibandronate administered daily or intermittently on fracture risk in postmenopausal osteoporosis. J Bone Miner Res 19:1241\u20131249","journal-title":"J Bone Miner Res"},{"key":"1664_CR27","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1056\/NEJMoa0809493","volume":"361","author":"S Cummings","year":"2009","unstructured":"Cummings S, Martin J, McClung M, Siris E, Eastell R, Reid I, Delmas P, Zoog H, Austin M, Wang A (2009) Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med 361:756","journal-title":"N Engl J Med"},{"key":"1664_CR28","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1056\/NEJM200105103441904","volume":"344","author":"R Neer","year":"2001","unstructured":"Neer R, Arnaud C, Zanchetta J, Prince R, Gaich G, Reginster J, Hodsman A, Eriksen E, Ish-Shalom S, Genant H (2001) Effect of parathyroid hormone (1\u201334) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 344:1434","journal-title":"N Engl J Med"},{"key":"1664_CR29","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1001\/jama.282.14.1344","volume":"282","author":"S Harris","year":"1999","unstructured":"Harris S, Watts N, Genant H, McKeever C, Hangartner T, Keller M, Chesnut C III, Brown J, Eriksen E, Hoseyni M (1999) Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Jama 282:1344","journal-title":"Jama"},{"key":"1664_CR30","doi-asserted-by":"crossref","first-page":"4118","DOI":"10.1210\/jc.85.11.4118","volume":"85","author":"D Black","year":"2000","unstructured":"Black D, Thompson D, Bauer D, Ensrud K, Musliner T, Hochberg M, Nevitt M, Suryawanshi S, Cummings S (2000) Fracture risk reduction with alendronate in women with osteoporosis: the Fracture Intervention Trial. J Clin Endocrinol Metab 85:4118","journal-title":"J Clin Endocrinol Metab"},{"key":"1664_CR31","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/S0140-6736(96)07088-2","volume":"348","author":"D Black","year":"1996","unstructured":"Black D, Cummings S, Karpf D, Cauley J, Thompson D, Nevitt M, Bauer D, Genant H, Haskell W, Marcus R (1996) Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Lancet 348:1535\u20131541","journal-title":"Lancet"},{"issue":"5","key":"1664_CR32","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.semarthrit.2005.11.001","volume":"35","author":"L Giangregorio","year":"2006","unstructured":"Giangregorio L, Papaioannou A, Cranney A, Zytaruk N, Adachi J (2006) Fragility fractures and the osteoporosis care gap: an international phenomenon. Semin Arthritis Rheum 35(5):293\u2013305","journal-title":"Semin Arthritis Rheum"},{"key":"1664_CR33","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00198-007-0483-0","volume":"19","author":"A Papaioannou","year":"2008","unstructured":"Papaioannou A, Kennedy C, Ioannidis G, Gao Y, Sawka A, Goltzman D, Tenenhouse A, Pickard L, Olszynski W, Davison K (2008) The osteoporosis care gap in men with fragility fractures: the Canadian Multicentre Osteoporosis Study. Osteoporos Int 19:581\u2013587","journal-title":"Osteoporos Int"},{"key":"1664_CR34","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s00198-007-0426-9","volume":"19","author":"L Bessette","year":"2008","unstructured":"Bessette L, Ste-Marie L, Jean S, Davison K, Beaulieu M, Baranci M, Bessant J, Brown J (2008) The care gap in diagnosis and treatment of women with a fragility fracture. Osteoporos Int 19:79\u201386","journal-title":"Osteoporos Int"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-011-1664-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-011-1664-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-011-1664-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T15:08:39Z","timestamp":1558624119000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-011-1664-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,21]]},"references-count":34,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["1664"],"URL":"https:\/\/doi.org\/10.1007\/s00198-011-1664-4","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,6,21]]}}}