{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T05:04:36Z","timestamp":1773291876766,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"S8","license":[{"start":{"date-parts":[[2012,11,22]],"date-time":"2012-11-22T00:00:00Z","timestamp":1353542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1007\/s00198-012-2166-8","type":"journal-article","created":{"date-parts":[[2012,11,22]],"date-time":"2012-11-22T19:26:40Z","timestamp":1353612400000},"page":"867-869","source":"Crossref","is-referenced-by-count":10,"title":["MRI in OA: from cartilage to bone marrow lesion"],"prefix":"10.1007","volume":"23","author":[{"given":"D.","family":"Loeuille","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Chary-valckenaere","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,11,22]]},"reference":[{"key":"2166_CR1","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/art.1780290816","volume":"29","author":"R Altman","year":"1986","unstructured":"Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K et al (1986) Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 29:1039\u20131049","journal-title":"Arthritis Rheum"},{"key":"2166_CR2","doi-asserted-by":"crossref","first-page":"2488","DOI":"10.1002\/art.22016","volume":"54","author":"DJ Hunter","year":"2006","unstructured":"Hunter DJ, Zhang YQ, Tu X, Lavalley M, Niu JB, Amin S, Guermazi A, Genant H, Gale D, Felson DT (2006) Change in joint space width: hyaline articular cartilage loss or alteration in meniscus? Arthritis Rheum 54:2488\u20132495","journal-title":"Arthritis Rheum"},{"key":"2166_CR3","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1002\/1529-0131(199806)41:6<963::AID-ART3>3.0.CO;2-3","volume":"41","author":"D Loeuille","year":"1998","unstructured":"Loeuille D, Olivier P, Mainard D, Gillet P, Netter P, Blum A (1998) Magnetic resonance imaging of normal and osteoarthritic cartilage. Arthritis Rheum 41:963\u2013975","journal-title":"Arthritis Rheum"},{"key":"2166_CR4","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.joca.2003.11.003","volume":"12","author":"CG Peterfy","year":"2004","unstructured":"Peterfy CG, Guermazi A, Zaim S, Tirman PF, Miaux Y, White D et al (2004) Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. Osteoarthr Cartil 12:177\u2013190","journal-title":"Osteoarthr Cartil"},{"key":"2166_CR5","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1136\/ard.2006.066183","volume":"67","author":"DJ Hunter","year":"2008","unstructured":"Hunter DJ, Lo GH, Gale D, Grainger AJ, Guermazi A, Conaghan PG (2008) The reliability of a new scoring system for knee osteoarthritis MRI and the validity of bone marrow lesion assessment: BLOKS (Boston Leeds Osteoarthritis Knee Score). Ann Rheum Dis 67:206\u2013211","journal-title":"Ann Rheum Dis"},{"key":"2166_CR6","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2214\/ajr.162.1.8273700","volume":"162","author":"LS Broderick","year":"1994","unstructured":"Broderick LS, Turner UA, Renfrew DL, Schnitzer TJ, Huff JP, Harris C (1994) Severity of articular cartilage abnormality in patients with osteoarthritis: evaluation with fast spin-echo MR vs arthroscopy. Am J Roentgenol 162:99\u2013103","journal-title":"Am J Roentgenol"},{"key":"2166_CR7","doi-asserted-by":"crossref","first-page":"541","DOI":"10.7326\/0003-4819-134-7-200104030-00007","volume":"134","author":"DT Felson","year":"2001","unstructured":"Felson DT, Chaisson CE, Hill CL, Totterman SM, Gale ME, Skinner KM, Kazis L, Gale DR (2001) The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med 134:541\u2013549","journal-title":"Ann Intern Med"},{"key":"2166_CR8","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.joca.2009.08.018","volume":"18","author":"FW Roemer","year":"2010","unstructured":"Roemer FW, Neogi T, Nevitt MC, Felson DT, Zhu Y, Zhang Y, Lynch JA, Javaid MK, Crema MD, Torner J, Lewis CE, Guermazi A (2010) Subchondral bone marrow lesions are highly associated with, and predict subchondral bone attrition longitudinally: the MOST study. Osteoarthr Cartil 18:47\u201353","journal-title":"Osteoarthr Cartil"},{"key":"2166_CR9","doi-asserted-by":"crossref","first-page":"R223","DOI":"10.1186\/ar3210","volume":"12","author":"D Dore","year":"2010","unstructured":"Dore D, Quinn S, Ding C, Winzenberg T, Zhai G, Cicuttini F, Jones G (2010) Natural history and clinical significance of MRI-detected bone marrow lesions at the knee: a prospective study in community dwelling older adults. Arthritis Res Ther 12:R223","journal-title":"Arthritis Res Ther"},{"key":"2166_CR10","doi-asserted-by":"crossref","first-page":"330","DOI":"10.7326\/0003-4819-139-5_Part_1-200309020-00008","volume":"139","author":"DT Felson","year":"2003","unstructured":"Felson DT, McLaughlin S, Goggins J, LaValley MP, Gale ME, Totterman S, Li W, Hill C, Gale D (2003) Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 139:330\u2013336","journal-title":"Ann Intern Med"},{"key":"2166_CR11","doi-asserted-by":"crossref","first-page":"657","DOI":"10.2214\/ajr.179.3.1790657","volume":"179","author":"N Boutry","year":"2002","unstructured":"Boutry N, Paul C, Lery X, Fredoux D, Migaud H, Cotton A (2002) Rapidly destructive osteoarthritis of the hip: MR imaging findings. Am J Roentgenol 179:657\u2013663","journal-title":"Am J Roentgenol"},{"key":"2166_CR12","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1148\/radiology.215.3.r00jn05835","volume":"15","author":"M Zanetti","year":"2000","unstructured":"Zanetti M, Bruder E, Romero J, Hodler J (2000) Bone marrow edema pattern in osteoarthritic knees: correlation between MR imaging and histologic findings. Radiology 15:835\u2013840","journal-title":"Radiology"},{"key":"2166_CR13","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.joca.2008.11.014","volume":"17","author":"GH Lo","year":"2009","unstructured":"Lo GH (2009) Strong association of MRI meniscal derangement and bone marrow lesion in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthr Cartil 17:743\u2013747","journal-title":"Osteoarthr Cartil"},{"key":"2166_CR14","doi-asserted-by":"crossref","first-page":"R11","DOI":"10.1186\/ar2601","volume":"11","author":"DJ Hunter","year":"2009","unstructured":"Hunter DJ, Gerstenfeld L, Bishop G, Davis AD, Mason ZD, Einhorn TA, Maciewicz RA, Newham P, Foster M, Jackson S, Morgan EF (2009) Bone marrow lesions from osteoarthritis knees are characterized by sclerotic bone that is less well mineralized. Arthritis Res Ther 11:R11","journal-title":"Arthritis Res Ther"},{"issue":"64","key":"2166_CR15","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1136\/ard.2005.039263","volume":"5","author":"P Conaghan","year":"2005","unstructured":"Conaghan P, Vanhoranta H, Dippe P (2005) Is progressive osteoarthritis an atheromatous vascular disease. Ann Rheum Dis 5(64):1539\u20131541","journal-title":"Ann Rheum Dis"},{"key":"2166_CR16","doi-asserted-by":"crossref","first-page":"2726","DOI":"10.1002\/art.27595","volume":"62","author":"MD Jones","year":"2010","unstructured":"Jones MD, Tran CW, Li G, Maksymowych WP, Zernicke RF, Doschak MR (2010) In vivo microfocal computed tomography and micro-magnetic resonance imaging evaluation of antiresorptive and antiinflammatory drugs as preventive treatments of osteoarthritis in the rat. Arthritis Rheum 62:2726\u20132735","journal-title":"Arthritis Rheum"},{"key":"2166_CR17","doi-asserted-by":"crossref","first-page":"3494","DOI":"10.1002\/art.22160","volume":"54","author":"CO Bingham","year":"2006","unstructured":"Bingham CO, Buckland-Wright JC, Garnero P, Cohen SB, Dougados M, Adami S et al (2006) Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis structural arthritis study. Arthritis Rheum 54:3494\u20133507","journal-title":"Arthritis Rheum"},{"key":"2166_CR18","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1136\/ard.2007.073023","volume":"67","author":"JP Raynauld","year":"2008","unstructured":"Raynauld JP, Martel-Pelletier J, Berthiaume MJ, Abram F, Choquette D, Haraoui B, Beary JF, Cline GA, Meyer JM, Martel-Pelletier JP (2008) Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period. Ann Rheum Dis 67:683\u2013688","journal-title":"Ann Rheum Dis"},{"key":"2166_CR19","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1002\/art.24486","volume":"60","author":"C Ding","year":"2009","unstructured":"Ding C, Cicuttini F, Parameswaran V, Burgess J, Quinn S, Jones G (2009) Serum levels of vitamin D, sunlight exposure, and knee cartilage loss in older adults: the Tasmanian older adult cohort study. Arthritis Rheum 60:1381\u20131389","journal-title":"Arthritis Rheum"},{"key":"2166_CR20","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1002\/art.22292","volume":"1","author":"DT Felson","year":"2007","unstructured":"Felson DT, Niu J, Clancy M, Aliabadi P, Sack B, Guermazi A, Hunter DJ, Amin S, Rogers G, Booth SL (2007) Low levels of vitamin D and worsening of knee osteoarthritis: results of two longitudinal studies. Arthritis Rheum 1:129\u2013136","journal-title":"Arthritis Rheum"},{"key":"2166_CR21","first-page":"S294","volume":"62","author":"TE Mc Alindon","year":"2010","unstructured":"Mc Alindon TE, Dawson-Hughes B, Driban J, LaValley M, Lee JY, Lo GH, Nuite M, Price LL (2010) Clinical trial of vitamin D to reduce pain and structural progression of knee osteoarthritis (OA). Arthritis Rheum 62:S294","journal-title":"Arthritis Rheum"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-012-2166-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-012-2166-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-012-2166-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T15:08:50Z","timestamp":1558624130000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-012-2166-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,22]]},"references-count":21,"journal-issue":{"issue":"S8","published-print":{"date-parts":[[2012,12]]}},"alternative-id":["2166"],"URL":"https:\/\/doi.org\/10.1007\/s00198-012-2166-8","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,22]]}}}