{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T19:30:44Z","timestamp":1793302244351,"version":"4.5.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,7,16]],"date-time":"2015-07-16T00:00:00Z","timestamp":1437004800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1007\/s00198-015-3226-7","type":"journal-article","created":{"date-parts":[[2015,7,15]],"date-time":"2015-07-15T05:13:38Z","timestamp":1436937218000},"page":"161-170","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Myostatin deficiency partially rescues the bone phenotype of osteogenesis imperfecta model mice"],"prefix":"10.1007","volume":"27","author":[{"given":"A. K.","family":"Oestreich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Carleton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B. A.","family":"Gentry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. E.","family":"Raw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. M.","family":"Pfeiffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7761-3783","authenticated-orcid":false,"given":"C. L.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,7,16]]},"reference":[{"key":"3226_CR1","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1002\/ajmg.a.36545","volume":"164","author":"FS Dijk Van","year":"2014","unstructured":"Van Dijk FS, Sillence DO (2014) Osteogenesis imperfecta: clinical diagnosis, nomenclature and severity assessment. Am J Med Genet A 164:1470\u20131481","journal-title":"Am J Med Genet A"},{"key":"3226_CR2","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1007\/s00223-012-9588-3","volume":"90","author":"T Cundy","year":"2012","unstructured":"Cundy T (2012) Recent advances in osteogenesis imperfecta. Calcif Tissue Int 90:439\u2013449","journal-title":"Calcif Tissue Int"},{"key":"3226_CR3","doi-asserted-by":"crossref","first-page":"E356","DOI":"10.1210\/jc.2013-3209","volume":"99","author":"LN Veilleux","year":"2014","unstructured":"Veilleux LN, Lemay M, Pouliot-Laforte A, Cheung MS, Glorieux FH, Rauch F (2014) Muscle anatomy and dynamic muscle function in osteogenesis imperfecta type I. J Clin Endocrinol Metab 99:E356\u2013E362","journal-title":"J Clin Endocrinol Metab"},{"key":"3226_CR4","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1073\/pnas.90.5.1701","volume":"90","author":"SD Chipman","year":"1993","unstructured":"Chipman SD, Sweet HO, McBride DJ Jr, Davisson MT, Marks SC Jr, Shuldiner AR, Wenstrup RJ, Rowe DW, Shapiro JR (1993) Defective pro alpha 2(I) collagen synthesis in a recessive mutation in mice: a model of human osteogenesis imperfecta. Proc Natl Acad Sci U S A 90:1701\u20131705","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3226_CR5","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1007\/s002239900412","volume":"62","author":"DJ McBride Jr","year":"1998","unstructured":"McBride DJ Jr, Shapiro JR, Dunn MG (1998) Bone geometry and strength measurements in aging mice with the oim mutation. Calcif Tissue Int 62:172\u2013176","journal-title":"Calcif Tissue Int"},{"key":"3226_CR6","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1359\/jbmr.1999.14.2.264","volume":"14","author":"NP Camacho","year":"1999","unstructured":"Camacho NP, Hou L, Toledano TR, Ilg WA, Brayton CF, Raggio CL, Root L, Boskey AL (1999) The material basis for reduced mechanical properties in oim mice bones. J Bone Miner Res 14:264\u2013272","journal-title":"J Bone Miner Res"},{"key":"3226_CR7","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.matbio.2010.06.006","volume":"29","author":"BA Gentry","year":"2010","unstructured":"Gentry BA, Ferreira JA, McCambridge AJ, Brown M, Phillips CL (2010) Skeletal muscle weakness in osteogenesis imperfecta mice. Matrix Biol 29:638\u2013644","journal-title":"Matrix Biol"},{"key":"3226_CR8","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S8756-3282(96)00305-5","volume":"19","author":"J Saban","year":"1996","unstructured":"Saban J, Zussman MA, Havey R, Patwardhan AG, Schneider GB, King D (1996) Heterozygous oim mice exhibit a mild form of osteogenesis imperfecta. Bone 19:575\u2013579","journal-title":"Bone"},{"key":"3226_CR9","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1007\/s10439-013-0793-7","volume":"41","author":"X Yao","year":"2013","unstructured":"Yao X, Carleton SM, Kettle AD, Melander J, Phillips CL, Wang Y (2013) Gender-dependence of bone structure and properties in adult osteogenesis imperfecta murine model. Ann Biomed Eng 41:1139\u20131149","journal-title":"Ann Biomed Eng"},{"key":"3226_CR10","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1002\/jbmr.2172","volume":"29","author":"A Carriero","year":"2014","unstructured":"Carriero A, Zimmermann EA, Paluszny A, Tang SY, Bale H, Busse B, Alliston T, Kazakia G, Ritchie RO, Shefelbine SJ (2014) How tough is brittle bone? investigating osteogenesis imperfecta in mouse bone. J Bone Miner Res 29:1392\u20131401","journal-title":"J Bone Miner Res"},{"key":"3226_CR11","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1359\/JBMR.041222","volume":"20","author":"SJ Warden","year":"2005","unstructured":"Warden SJ, Hurst JA, Sanders MS, Turner CH, Burr DB, Li J (2005) Bone adaptation to a mechanical loading program significantly increases skeletal fatigue resistance. J Bone Miner Res 20:809\u2013816","journal-title":"J Bone Miner Res"},{"key":"3226_CR12","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1196\/annals.1346.039","volume":"1068","author":"CH Turner","year":"2006","unstructured":"Turner CH (2006) Bone strength: current concepts. Ann N Y Acad Sci 1068:429\u2013446","journal-title":"Ann N Y Acad Sci"},{"key":"3226_CR13","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/s002230010060","volume":"66","author":"Y Kodama","year":"2000","unstructured":"Kodama Y, Umemura Y, Nagasawa S, Beamer WG, Donahue LR, Rosen CR, Baylink DJ, Farley JR (2000) Exercise and mechanical loading increase periosteal bone formation and whole bone strength in C57BL\/6J mice but not in C3H\/Hej mice. Calcif Tissue Int 66:298\u2013306","journal-title":"Calcif Tissue Int"},{"key":"3226_CR14","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1359\/JBMR.051203","volume":"21","author":"MW Hamrick","year":"2006","unstructured":"Hamrick MW, Samaddar T, Pennington C, McCormick J (2006) Increased muscle mass with myostatin deficiency improves gains in bone strength with exercise. J Bone Miner Res 21:477\u2013483","journal-title":"J Bone Miner Res"},{"key":"3226_CR15","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1152\/japplphysiol.01091.2007","volume":"104","author":"HD Kollias","year":"2008","unstructured":"Kollias HD, McDermott JC (2008) Transforming growth factor-beta and myostatin signaling in skeletal muscle. J Appl Physiol 104:579\u2013587","journal-title":"J Appl Physiol"},{"key":"3226_CR16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/387083a0","volume":"387","author":"AC McPherron","year":"1997","unstructured":"McPherron AC, Lawler AM, Lee SJ (1997) Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387:83\u201390","journal-title":"Nature"},{"key":"3226_CR17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/mus.21796","volume":"43","author":"BA Gentry","year":"2011","unstructured":"Gentry BA, Ferreira JA, Phillips CL, Brown M (2011) Hindlimb skeletal muscle function in myostatin-deficient mice. Muscle Nerve 43:49\u201357","journal-title":"Muscle Nerve"},{"key":"3226_CR18","doi-asserted-by":"crossref","first-page":"e79","DOI":"10.1371\/journal.pgen.0030079","volume":"3","author":"DS Mosher","year":"2007","unstructured":"Mosher DS, Quignon P, Bustamante CD, Sutter NB, Mellersh CS, Parker HG, Ostrander EA (2007) A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet 3:e79","journal-title":"PLoS Genet"},{"key":"3226_CR19","first-page":"56","volume":"10","author":"MN Elkasrawy","year":"2010","unstructured":"Elkasrawy MN, Hamrick MW (2010) Myostatin (GDF-8) as a key factor linking muscle mass and bone structure. J Musculoskelet Neuronal Interact 10:56\u201363","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"3226_CR20","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1359\/jbmr.2001.16.7.1195","volume":"16","author":"WG Beamer","year":"2001","unstructured":"Beamer WG, Shultz KL, Donahue LR, Churchill GA, Sen S, Wergedal JR, Baylink DJ, Rosen CJ (2001) Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL\/6J and C3H\/HeJ inbred strains of mice. J Bone Miner Res 16:1195\u20131206","journal-title":"J Bone Miner Res"},{"key":"3226_CR21","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.bone.2007.12.215","volume":"42","author":"SM Carleton","year":"2008","unstructured":"Carleton SM, McBride DJ, Carson WL, Huntington CE, Twenter KL, Rolwes KM, Winkelmann CT, Morris JS, Taylor JF, Phillips CL (2008) Role of genetic background in determining phenotypic severity throughout postnatal development and at peak bone mass in Col1a2 deficient mice (oim). Bone 42:681\u2013694","journal-title":"Bone"},{"key":"3226_CR22","doi-asserted-by":"crossref","unstructured":"Mandair GS, Morris MD (2015) Contributions of Raman spectroscopy to the understanding of bone strength. BoneKEy Rep 4","DOI":"10.1038\/bonekey.2014.115"},{"key":"3226_CR23","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0009-8981(67)90167-2","volume":"18","author":"H Stegemann","year":"1967","unstructured":"Stegemann H, Stalder K (1967) Determination of hydroxyproline. Clin Chim Acta 18:267\u2013273","journal-title":"Clin Chim Acta"},{"key":"3226_CR24","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1038\/nrrheum.2012.86","volume":"8","author":"K Naylor","year":"2012","unstructured":"Naylor K, Eastell R (2012) Bone turnover markers: use in osteoporosis. Nat Rev Rheumatol 8:379\u2013389","journal-title":"Nat Rev Rheumatol"},{"key":"3226_CR25","doi-asserted-by":"crossref","first-page":"e789","DOI":"10.1371\/journal.pone.0000789","volume":"2","author":"SJ Lee","year":"2007","unstructured":"Lee SJ (2007) Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways. PLoS One 2:e789","journal-title":"PLoS One"},{"key":"3226_CR26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s00223-001-1109-8","volume":"71","author":"MW Hamrick","year":"2002","unstructured":"Hamrick MW, McPherron AC, Lovejoy CO (2002) Bone mineral content and density in the humerus of adult myostatin-deficient mice. Calcif Tissue Int 71:63\u201368","journal-title":"Calcif Tissue Int"},{"key":"3226_CR27","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/ar.a.10044","volume":"272","author":"MW Hamrick","year":"2003","unstructured":"Hamrick MW (2003) Increased bone mineral density in the femora of GDF8 knockout mice. Anat Rec A: Discov Mol Cell Evol Biol 272:388\u2013391","journal-title":"Anat Rec A: Discov Mol Cell Evol Biol"},{"key":"3226_CR28","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1002\/jcb.21337","volume":"102","author":"H Zhang","year":"2007","unstructured":"Zhang H, Doty SB, Hughes C, Dempster D, Camacho NP (2007) Increased resorptive activity and accompanying morphological alterations in osteoclasts derived from the oim\/oim mouse model of osteogenesis imperfecta. J Cell Biochem 102:1011\u20131020","journal-title":"J Cell Biochem"},{"key":"3226_CR29","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1359\/jbmr.080804","volume":"23","author":"TE Uveges","year":"2008","unstructured":"Uveges TE, Collin-Osdoby P, Cabral WA, Ledgard F, Goldberg L, Bergwitz C, Forlino A, Osdoby P, Gronowicz GA, Marini JC (2008) Cellular mechanism of decreased bone in Brtl mouse model of OI: imbalance of decreased osteoblast function and increased osteoclasts and their precursors. J Bone Miner Res 23:1983\u20131994","journal-title":"J Bone Miner Res"},{"key":"3226_CR30","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1002\/jbmr.2177","volume":"29","author":"F Chen","year":"2014","unstructured":"Chen F, Guo R, Itoh S et al (2014) First mouse model for combined osteogenesis imperfecta and Ehlers-Danlos syndrome. J Bone Miner Res 29:1412\u20131423","journal-title":"J Bone Miner Res"},{"key":"3226_CR31","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.2353\/ajpath.2010.090704","volume":"176","author":"H Li","year":"2010","unstructured":"Li H, Jiang X, Delaney J, Franceschetti T, Bilic-Curcic I, Kalinovsky J, Lorenzo JA, Grcevic D, Rowe DW, Kalajzic I (2010) Immature osteoblast lineage cells increase osteoclastogenesis in osteogenesis imperfecta murine. Am J Pathol 176:2405\u20132413","journal-title":"Am J Pathol"},{"key":"3226_CR32","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1002\/stem.1107","volume":"30","author":"R Gioia","year":"2012","unstructured":"Gioia R, Panaroni C, Besio R et al (2012) Impaired osteoblastogenesis in a murine model of dominant osteogenesis imperfecta: a new target for osteogenesis imperfecta pharmacological therapy. Stem Cells 30:1465\u20131476","journal-title":"Stem Cells"},{"key":"3226_CR33","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.bone.2012.08.110","volume":"51","author":"RM Coleman","year":"2012","unstructured":"Coleman RM, Aguilera L, Quinones L, Lukashova L, Poirier C, Boskey A (2012) Comparison of bone tissue properties in mouse models with collagenous and non-collagenous genetic mutations using FTIRI. Bone 51:920\u2013928","journal-title":"Bone"},{"key":"3226_CR34","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3109\/03008209609029199","volume":"35","author":"NP Camacho","year":"1996","unstructured":"Camacho NP, Landis WJ, Boskey AL (1996) Mineral changes in a mouse model of osteogenesis imperfecta detected by Fourier transform infrared microscopy. Connect Tissue Res 35:259\u2013265","journal-title":"Connect Tissue Res"},{"key":"3226_CR35","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s11914-014-0209-0","volume":"12","author":"M Brotto","year":"2014","unstructured":"Brotto M, Johnson ML (2014) Endocrine crosstalk between muscle and bone. Curr Osteop Rep 12:135\u2013141","journal-title":"Curr Osteop Rep"},{"key":"3226_CR36","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1016\/j.bone.2007.02.012","volume":"40","author":"MW Hamrick","year":"2007","unstructured":"Hamrick MW, Shi X, Zhang W, Pennington C, Thakore H, Haque M, Kang B, Isales CM, Fulzele S, Wenger KH (2007) Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading. Bone 40:1544\u20131553","journal-title":"Bone"},{"key":"3226_CR37","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1369\/0022155411425389","volume":"60","author":"M Elkasrawy","year":"2012","unstructured":"Elkasrawy M, Immel D, Wen X, Liu X, Liang LF, Hamrick MW (2012) Immunolocalization of myostatin (GDF-8) following musculoskeletal injury and the effects of exogenous myostatin on muscle and bone healing. J Histochem Cytochem : Off J Histochem Soc 60:22\u201330","journal-title":"J Histochem Cytochem : Off J Histochem Soc"},{"key":"3226_CR38","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1097\/TA.0b013e3181c451f4","volume":"69","author":"MW Hamrick","year":"2010","unstructured":"Hamrick MW, Arounleut P, Kellum E, Cain M, Immel D, Liang LF (2010) Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury. J Trauma 69:579\u2013583","journal-title":"J Trauma"},{"key":"3226_CR39","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.cellsig.2004.02.007","volume":"16","author":"F Verrecchia","year":"2004","unstructured":"Verrecchia F, Mauviel A (2004) TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression. Cell Signal 16:873\u2013880","journal-title":"Cell Signal"},{"key":"3226_CR40","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1177\/153537020222700502","volume":"227","author":"AK Ghosh","year":"2002","unstructured":"Ghosh AK (2002) Factors involved in the regulation of type I collagen gene expression: implication in fibrosis. Exp Biol Med (Maywood) 227:301\u2013314","journal-title":"Exp Biol Med (Maywood)"},{"key":"3226_CR41","doi-asserted-by":"crossref","unstructured":"Hosaka YZ, Ishibashi M, Wakamatsu J, Uehara M, Nishimura T (2012) Myostatin regulates proliferation and extracellular matrix mRNA expression in NIH3T3 fibroblasts. Biomed Res 33:355\u2013361","DOI":"10.2220\/biomedres.33.355"},{"key":"3226_CR42","doi-asserted-by":"crossref","first-page":"19371","DOI":"10.1074\/jbc.M802585200","volume":"283","author":"ZB Li","year":"2008","unstructured":"Li ZB, Kollias HD, Wagner KR (2008) Myostatin directly regulates skeletal muscle fibrosis. J Biol Chem 283:19371\u201319378","journal-title":"J Biol Chem"},{"key":"3226_CR43","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1111\/j.1469-7580.2012.01503.x","volume":"220","author":"MI Elashry","year":"2012","unstructured":"Elashry MI, Collins-Hooper H, Vaiyapuri S, Patel K (2012) Characterisation of connective tissue from the hypertrophic skeletal muscle of myostatin null mice. J Anat 220:603\u2013611","journal-title":"J Anat"},{"key":"3226_CR44","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1073\/pnas.0707069105","volume":"105","author":"CL Mendias","year":"2008","unstructured":"Mendias CL, Bakhurin KI, Faulkner JA (2008) Tendons of myostatin-deficient mice are small, brittle, and hypocellular. Proc Natl Acad Sci U S A 105:388\u2013393","journal-title":"Proc Natl Acad Sci U S A"},{"key":"3226_CR45","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/jmbi.1997.1106","volume":"270","author":"DJ McBride Jr","year":"1997","unstructured":"McBride DJ Jr, Choe V, Shapiro JR, Brodsky B (1997) Altered collagen structure in mouse tail tendon lacking the alpha 2(I) chain. J Mol Biol 270:275\u2013284","journal-title":"J Mol Biol"},{"key":"3226_CR46","doi-asserted-by":"crossref","unstructured":"Chiu CS, Peekhaus N, Weber H, et al. (2013) Increased muscle force production and bone mineral density in ActRIIB-Fc-treated mature rodents. J Gerontol A Biol Sci Med Sci","DOI":"10.1093\/gerona\/glt030"},{"key":"3226_CR47","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.bone.2013.12.002","volume":"60","author":"P Bialek","year":"2014","unstructured":"Bialek P, Parkington J, Li X et al (2014) A myostatin and activin decoy receptor enhances bone formation in mice. Bone 60:162\u2013171","journal-title":"Bone"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-015-3226-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-015-3226-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-015-3226-7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,28]],"date-time":"2019-08-28T03:40:12Z","timestamp":1566963612000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-015-3226-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,16]]},"references-count":47,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,1]]}},"alternative-id":["3226"],"URL":"https:\/\/doi.org\/10.1007\/s00198-015-3226-7","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,16]]}}}