{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T14:12:22Z","timestamp":1790259142307,"version":"4.1.0"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2015,9,22]],"date-time":"2015-09-22T00:00:00Z","timestamp":1442880000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1007\/s00198-015-3326-4","type":"journal-article","created":{"date-parts":[[2015,9,22]],"date-time":"2015-09-22T06:13:26Z","timestamp":1442902406000},"page":"1149-1160","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Bone architecture adaptations after spinal cord injury: impact of long-term vibration of a constrained lower limb"],"prefix":"10.1007","volume":"27","author":[{"given":"S.","family":"Dudley-Javoroski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A.","family":"Petrie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. L.","family":"McHenry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. E.","family":"Amelon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. K.","family":"Saha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. K.","family":"Shields","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,9,22]]},"reference":[{"key":"3326_CR1","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1007\/s11914-010-0029-9","volume":"8","author":"W Qin","year":"2010","unstructured":"Qin W, Bauman WA, Cardozo CP (2010) Evolving concepts in neurogenic osteoporosis. Curr Osteoporos Rep 8:212\u2013218","journal-title":"Curr Osteoporos Rep"},{"key":"3326_CR2","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1007\/s00198-013-2557-5","volume":"25","author":"WB Edwards","year":"2014","unstructured":"Edwards WB, Schnitzer TJ, Troy KL (2014) Bone mineral and stiffness loss at the distal femur and proximal tibia in acute spinal cord injury. Osteoporos Int 25:1005\u20131015","journal-title":"Osteoporos Int"},{"key":"3326_CR3","doi-asserted-by":"publisher","first-page":"1365","DOI":"10.1682\/JRRD.2011.12.0245","volume":"49","author":"S Dudley-Javoroski","year":"2012","unstructured":"Dudley-Javoroski S, Shields RK (2012) Regional cortical and trabecular bone loss after spinal cord injury. J Rehabil Res Dev 49:1365\u20131376","journal-title":"J Rehabil Res Dev"},{"key":"3326_CR4","doi-asserted-by":"publisher","first-page":"2335","DOI":"10.1007\/s00198-011-1879-4","volume":"23","author":"S Dudley-Javoroski","year":"2012","unstructured":"Dudley-Javoroski S, Saha PK, Liang G, Li C, Gao Z, Shields RK (2012) High dose compressive loads attenuate bone mineral loss in humans with spinal cord injury. Osteoporos Int 23:2335\u20132346","journal-title":"Osteoporos Int"},{"key":"3326_CR5","first-page":"227","volume":"8","author":"S Dudley-Javoroski","year":"2008","unstructured":"Dudley-Javoroski S, Shields RK (2008) Asymmetric bone adaptations to soleus mechanical loading after spinal cord injury. J Musculoskelet Neuronal Interact 8:227\u2013238","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"3326_CR6","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1179\/2045772313Y.0000000092","volume":"36","author":"S Dudley-Javoroski","year":"2013","unstructured":"Dudley-Javoroski S, Shields RK (2013) Active-resisted stance modulates regional bone mineral density in humans with spinal cord injury. J Spinal Cord Med 36:191\u2013199","journal-title":"J Spinal Cord Med"},{"key":"3326_CR7","doi-asserted-by":"publisher","first-page":"2380","DOI":"10.1152\/jn.01181.2005","volume":"95","author":"RK Shields","year":"2006","unstructured":"Shields RK, Dudley-Javoroski S (2006) Musculoskeletal plasticity after acute spinal cord injury: Effects of long-term neuromuscular electrical stimulation training. J Neurophysiol 95:2380\u20132390","journal-title":"J Neurophysiol"},{"key":"3326_CR8","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1016\/S0003-9993(98)90184-8","volume":"79","author":"A Hartkopp","year":"1998","unstructured":"Hartkopp A, Murphy RJ, Mohr T, Kjaer M, Biering-Sorensen F (1998) Bone fracture during electrical stimulation of the quadriceps in a spinal cord injured subject. Arch Phys Med Rehabil 79:1133\u20131136","journal-title":"Arch Phys Med Rehabil"},{"key":"3326_CR9","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1177\/1545968310366129","volume":"24","author":"H Kern","year":"2010","unstructured":"Kern H, Carraro U, Adami N et al (2010) Home-based functional electrical stimulation rescues permanently denervated muscles in paraplegic patients with complete lower motor neuron lesion. Neurorehabil Neural Repair 24:709\u2013721","journal-title":"Neurorehabil Neural Repair"},{"key":"3326_CR10","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/S0021-9290(99)00210-9","volume":"33","author":"SP Fritton","year":"2000","unstructured":"Fritton SP, McLeod KJ, Rubin CT (2000) Quantifying the strain history of bone: spatial uniformity and self-similarity of low-magnitude strains. J Biomech 33:317\u2013325","journal-title":"J Biomech"},{"key":"3326_CR11","doi-asserted-by":"publisher","first-page":"e653","DOI":"10.1371\/journal.pone.0000653","volume":"2","author":"R Garman","year":"2007","unstructured":"Garman R, Rubin C, Judex S (2007) Small oscillatory accelerations, independent of matrix deformations, increase osteoblast activity and enhance bone morphology. PLoS ONE 2:e653","journal-title":"PLoS ONE"},{"key":"3326_CR12","doi-asserted-by":"publisher","unstructured":"Bramlett HM, Dietrich WD, Marcillo A et al (2014) Effects of low intensity vibration on bone and muscle in rats with spinal cord injury. Osteoporos Int","DOI":"10.1007\/s00198-014-2748-8"},{"key":"3326_CR13","doi-asserted-by":"publisher","first-page":"3404","DOI":"10.1016\/j.jbiomech.2007.05.015","volume":"40","author":"E Ozcivici","year":"2007","unstructured":"Ozcivici E, Garman R, Judex S (2007) High-frequency oscillatory motions enhance the simulated mechanical properties of non-weight bearing trabecular bone. J Biomech 40:3404\u20133411","journal-title":"J Biomech"},{"key":"3326_CR14","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S8756-3282(01)00689-5","volume":"30","author":"C Rubin","year":"2002","unstructured":"Rubin C, Turner AS, Mallinckrodt C, Jerome C, McLeod K, Bain S (2002) Mechanical strain, induced noninvasively in the high-frequency domain, is anabolic to cancellous bone, but not cortical bone. Bone 30:445\u2013452","journal-title":"Bone"},{"key":"3326_CR15","doi-asserted-by":"publisher","first-page":"B352","DOI":"10.1093\/gerona\/54.8.B352","volume":"54","author":"RP Huang","year":"1999","unstructured":"Huang RP, Rubin CT, McLeod KJ (1999) Changes in postural muscle dynamics as a function of age. J Gerontol A Biol Sci Med Sci 54:B352\u2013B357","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"3326_CR16","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1179\/107902610x12886261091758","volume":"34","author":"P Asselin","year":"2011","unstructured":"Asselin P, Spungen AM, Muir JW, Rubin CT, Bauman WA (2011) Transmission of low-intensity vibration through the axial skeleton of persons with spinal cord injury as a potential intervention for preservation of bone quantity and quality. J Spinal Cord Med 34:52\u201359","journal-title":"J Spinal Cord Med"},{"key":"3326_CR17","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1123\/apaq.27.1.60","volume":"27","author":"R Davis","year":"2010","unstructured":"Davis R, Sanborn C, Nichols D, Bazett-Jones DM, Dugan EL (2010) The effects of whole body vibration on bone mineral density for a person with a spinal cord injury: a case study. Adapt Phys Act Q 27:60\u201372","journal-title":"Adapt Phys Act Q"},{"key":"3326_CR18","doi-asserted-by":"crossref","unstructured":"Wuermser LA, Beck LA, Lamb JL, Atkinson EJ, Amin S (2014) The effect of low-magnitude whole body vibration on bone density and microstructure in men and women with chronic motor complete paraplegia. J Spinal Cord Med","DOI":"10.1179\/2045772313Y.0000000191"},{"key":"3326_CR19","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1186\/1756-0500-7-334","volume":"7","author":"CL McHenry","year":"2014","unstructured":"McHenry CL, Wu J, Shields RK (2014) Potential regenerative rehabilitation technology: implications of mechanical stimuli to tissue health. BMC Res Notes 7:334","journal-title":"BMC Res Notes"},{"key":"3326_CR20","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1002\/jbmr.1501","volume":"27","author":"Y Bala","year":"2012","unstructured":"Bala Y, Depalle B, Farlay D, Douillard T, Meille S, Follet H, Chapurlat R, Chevalier J, Boivin G (2012) Bone micromechanical properties are compromised during long-term alendronate therapy independently of mineralization. J Bone Miner Res 27:825\u2013834","journal-title":"J Bone Miner Res"},{"key":"3326_CR21","doi-asserted-by":"publisher","first-page":"1049","DOI":"10.1185\/030079905X50525","volume":"21","author":"CD Rubin","year":"2005","unstructured":"Rubin CD (2005) Emerging concepts in osteoporosis and bone strength. Curr Med Res Opin 21:1049\u20131056","journal-title":"Curr Med Res Opin"},{"key":"3326_CR22","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1016\/j.jocd.2012.02.003","volume":"16","author":"L Giangregorio","year":"2013","unstructured":"Giangregorio L, Lala D, Hummel K, Gordon C, Craven BC (2013) Measuring apparent trabecular density and bone structure using peripheral quantitative computed tomography at the tibia: precision in participants with and without spinal cord injury. J Clin Densitom 16:139\u2013146","journal-title":"J Clin Densitom"},{"key":"3326_CR23","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1016\/j.bone.2013.12.012","volume":"60","author":"WB Edwards","year":"2014","unstructured":"Edwards WB, Schnitzer TJ, Troy KL (2014) The mechanical consequence of actual bone loss and simulated bone recovery in acute spinal cord injury. Bone 60:141\u2013147","journal-title":"Bone"},{"key":"3326_CR24","doi-asserted-by":"publisher","unstructured":"Edwards WB, Schnitzer TJ, Troy KL (2014) Reduction in proximal femoral strength in patients with acute spinal cord injury. J Bone Miner Res","DOI":"10.1002\/jbmr.2227"},{"key":"3326_CR25","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1179\/204577211X13207446293695","volume":"34","author":"SC Kirshblum","year":"2011","unstructured":"Kirshblum SC, Burns SP, Biering-Sorensen F, Donovan W, Graves DE, Jha A, Johansen M, Jones L, Krassioukov A, Mulcahey M, Schmidt-Read M, Waring W (2011) International Standards for Neurological Classification of Spinal Cord Injury (Revised 2011). J Spinal Cord Med 34:535\u2013546","journal-title":"J Spinal Cord Med"},{"key":"3326_CR26","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1007\/s00198-009-1044-5","volume":"21","author":"S Dudley-Javoroski","year":"2009","unstructured":"Dudley-Javoroski S, Shields RK (2009) Longitudinal changes in femur bone mineral density after spinal cord injury: effects of slice placement and peel method. Osteoporos Int 21:985\u2013995","journal-title":"Osteoporos Int"},{"key":"3326_CR27","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.1109\/TMI.2010.2050779","volume":"29","author":"PK Saha","year":"2010","unstructured":"Saha PK, Xu Y, Duan H, Heiner A, Liang G (2010) Volumetric topological analysis: a novel approach for trabecular bone classification on the continuum between plates and rods. IEEE Trans Med Imaging 29:1821\u20131838","journal-title":"IEEE Trans Med Imaging"},{"key":"3326_CR28","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1359\/jbmr.080108","volume":"23","author":"FW Wehrli","year":"2008","unstructured":"Wehrli FW, Ladinsky GA, Jones C et al (2008) In vivo magnetic resonance detects rapid remodeling changes in the topology of the trabecular bone network after menopause and the protective effect of estradiol. J Bone Miner Res 23:730\u2013740","journal-title":"J Bone Miner Res"},{"key":"3326_CR29","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1002\/jor.20354","volume":"25","author":"R Garman","year":"2007","unstructured":"Garman R, Gaudette G, Donahue LR, Rubin C, Judex S (2007) Low-level accelerations applied in the absence of weight bearing can enhance trabecular bone formation. J Orthop Res 25:732\u2013740","journal-title":"J Orthop Res"},{"key":"3326_CR30","doi-asserted-by":"publisher","unstructured":"Chang SH, Dudley-Javoroski S, Shields RK (2011) Gravitational force modulates muscle activity during mechanical oscillation of the tibia in humans. J Electromyogr Kinesiol","DOI":"10.1016\/j.jelekin.2011.06.001"},{"key":"3326_CR31","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/j.clinph.2011.08.001","volume":"123","author":"SH Chang","year":"2012","unstructured":"Chang SH, Tseng SC, McHenry CL, Littmann AE, Suneja M, Shields RK (2012) Limb segment vibration modulates spinal reflex excitability and muscle mRNA expression after spinal cord injury. Clin Neurophysiol 123:558\u2013568","journal-title":"Clin Neurophysiol"},{"key":"3326_CR32","first-page":"197","volume":"4","author":"P Eser","year":"2004","unstructured":"Eser P, Schiessl H, Willnecker J (2004) Bone loss and steady state after spinal cord injury: a cross-sectional study using pQCT. J Musculoskelet Neuronal Interact 4:197\u2013198","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"3326_CR33","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1016\/j.bone.2008.05.006","volume":"43","author":"A Frotzler","year":"2008","unstructured":"Frotzler A, Berger M, Knecht H, Eser P (2008) Bone steady-state is established at reduced bone strength after spinal cord injury: A longitudinal study using peripheral quantitative computed tomography (pQCT). Bone 43:549\u2013555","journal-title":"Bone"},{"key":"3326_CR34","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s001980050206","volume":"10","author":"WA Bauman","year":"1999","unstructured":"Bauman WA, Spungen AM, Wang J, Pierson RN Jr, Schwartz E (1999) Continuous loss of bone during chronic immobilization: a monozygotic twin study. Osteoporos Int 10:123\u2013127","journal-title":"Osteoporos Int"},{"key":"3326_CR35","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1177\/1545968306293447","volume":"21","author":"RK Shields","year":"2007","unstructured":"Shields RK, Dudley-Javoroski S (2007) Musculoskeletal adaptation in chronic spinal cord injury: effects of long-term soleus electrical stimulation training. J Neurorehabil Neural Repair 21:169\u2013179","journal-title":"J Neurorehabil Neural Repair"},{"key":"3326_CR36","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1016\/j.clinbiomech.2003.12.005","volume":"19","author":"L Frey Law","year":"2004","unstructured":"Frey Law L, Shields RK (2004) Femoral loads during passive, active, and active-resistive stance after spinal cord injury: a mathematical model. Clin Biomech 19:313\u2013321","journal-title":"Clin Biomech"},{"key":"3326_CR37","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1179\/2045772312Y.0000000011","volume":"35","author":"CL McHenry","year":"2012","unstructured":"McHenry CL, Shields RK (2012) A biomechanical analysis of exercise in standing, supine, and seated positions: implications for individuals with spinal cord injury. J Spinal Cord Med 35:140\u2013147","journal-title":"J Spinal Cord Med"},{"key":"3326_CR38","doi-asserted-by":"publisher","first-page":"1409","DOI":"10.1016\/S0026-0495(99)90151-8","volume":"48","author":"PD Chilibeck","year":"1999","unstructured":"Chilibeck PD, Bell G, Jeon J, Weiss CB, Murdoch G, MacLean I, Ryan E, Burnham R (1999) Functional electrical stimulation exercise increases GLUT-1 and GLUT-4 in paralyzed skeletal muscle. Metabolism 48:1409\u20131413","journal-title":"Metabolism"},{"key":"3326_CR39","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1249\/MSS.0b013e31822672aa","volume":"44","author":"AS Gorgey","year":"2012","unstructured":"Gorgey AS, Mather KJ, Cupp HR, Gater DR (2012) Effects of resistance training on adiposity and metabolism after spinal cord injury. Med Sci Sports Exerc 44:165\u2013174","journal-title":"Med Sci Sports Exerc"},{"key":"3326_CR40","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1016\/j.jelekin.2008.03.002","volume":"19","author":"L Griffin","year":"2008","unstructured":"Griffin L, Decker MJ, Hwang JY, Wang B, Kitchen K, Ding Z, Ivy JL (2008) Functional electrical stimulation cycling improves body composition, metabolic and neural factors in persons with spinal cord injury. J Electromyogr Kinesiol 19:614\u2013622","journal-title":"J Electromyogr Kinesiol"},{"key":"3326_CR41","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1016\/j.apmr.2010.08.024","volume":"91","author":"JY Jeon","year":"2010","unstructured":"Jeon JY, Hettinga D, Steadward RD, Wheeler GD, Bell G, Harber V (2010) Reduced plasma glucose and leptin after 12\u00a0weeks of functional electrical stimulation-rowing exercise training in spinal cord injury patients. Arch Phys Med Rehabil 91:1957\u20131959","journal-title":"Arch Phys Med Rehabil"},{"key":"3326_CR42","doi-asserted-by":"publisher","first-page":"1502","DOI":"10.1016\/j.apmr.2004.12.021","volume":"86","author":"ET Mahoney","year":"2005","unstructured":"Mahoney ET, Bickel CS, Elder C, Black C, Slade JM, Apple D Jr, Dudley GA (2005) Changes in skeletal muscle size and glucose tolerance with electrically stimulated resistance training in subjects with chronic spinal cord injury. Arch Phys Med Rehabil 86:1502\u20131504","journal-title":"Arch Phys Med Rehabil"},{"key":"3326_CR43","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.bone.2010.05.025","volume":"47","author":"J Rittweger","year":"2010","unstructured":"Rittweger J, Goosey-Tolfrey VL, Cointry G, Ferretti JL (2010) Structural analysis of the human tibia in men with spinal cord injury by tomographic (pQCT) serial scans. Bone 47:511\u2013518","journal-title":"Bone"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-015-3326-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-015-3326-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-015-3326-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-015-3326-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,30]],"date-time":"2019-08-30T17:11:30Z","timestamp":1567185090000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-015-3326-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,22]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3]]}},"alternative-id":["3326"],"URL":"https:\/\/doi.org\/10.1007\/s00198-015-3326-4","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,22]]}}}