{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T23:20:57Z","timestamp":1793488857122,"version":"4.5.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T00:00:00Z","timestamp":1511308800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1007\/s00198-017-4314-7","type":"journal-article","created":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T02:10:38Z","timestamp":1511316638000},"page":"615-623","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Independent association of bone mineral density and trabecular bone score to vertebral fracture in male subjects with chronic obstructive pulmonary disease"],"prefix":"10.1007","volume":"29","author":[{"given":"R.","family":"Watanabe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Tai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Ban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8311-0787","authenticated-orcid":false,"given":"D.","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Okazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,11,22]]},"reference":[{"issue":"9823","key":"4314_CR1","doi-asserted-by":"publisher","first-page":"1341","DOI":"10.1016\/s0140-6736(11)60968-9","volume":"379","author":"M Decramer","year":"2012","unstructured":"Decramer M, Janssens W, Miravitlles M (2012) Chronic obstructive pulmonary disease. Lancet 379(9823):1341\u20131351. \nhttps:\/\/doi.org\/10.1016\/s0140-6736(11)60968-9","journal-title":"Lancet"},{"issue":"1","key":"4314_CR2","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-015-0192-8","volume":"16","author":"EA Romme","year":"2015","unstructured":"Romme EA, Geusens P, Lems WF, Rutten EP, Smeenk FW, van den Bergh JP, van Hal PT, Wouters EF (2015) Fracture prevention in COPD patients; a clinical 5-step approach. Respir Res 16(1):32. \nhttps:\/\/doi.org\/10.1186\/s12931-015-0192-8","journal-title":"Respir Res"},{"key":"4314_CR3","doi-asserted-by":"publisher","first-page":"5","DOI":"10.4137\/ccrpm.s22803","volume":"9","author":"M Sarkar","year":"2015","unstructured":"Sarkar M, Bhardwaj R, Madabhavi I, Khatana J (2015) Osteoporosis in chronic obstructive pulmonary disease. Clin Med Insights Circ Respir Pulm Med 9:5\u201321. \nhttps:\/\/doi.org\/10.4137\/ccrpm.s22803","journal-title":"Clin Med Insights Circ Respir Pulm Med"},{"issue":"5","key":"4314_CR4","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.1378\/chest.07-1092","volume":"132","author":"P Vestergaard","year":"2007","unstructured":"Vestergaard P, Rejnmark L, Mosekilde L (2007) Fracture risk in patients with chronic lung diseases treated with bronchodilator drugs and inhaled and oral corticosteroids. Chest 132(5):1599\u20131607. \nhttps:\/\/doi.org\/10.1378\/chest.07-1092","journal-title":"Chest"},{"issue":"1","key":"4314_CR5","doi-asserted-by":"publisher","first-page":"11","DOI":"10.3109\/15412555.2012.723072","volume":"10","author":"EA Regan","year":"2013","unstructured":"Regan EA, Radcliff TA, Henderson WG, Cowper Ripley DC, Maciejewski ML, Vogel WB, Hutt E (2013) Improving hip fractures outcomes for COPD patients. COPD 10(1):11\u201319. \nhttps:\/\/doi.org\/10.3109\/15412555.2012.723072","journal-title":"COPD"},{"issue":"6","key":"4314_CR6","doi-asserted-by":"publisher","first-page":"1855","DOI":"10.1007\/s00198-010-1423-y","volume":"22","author":"NE Morden","year":"2011","unstructured":"Morden NE, Sullivan SD, Bartle B, Lee TA (2011) Skeletal health in men with chronic lung disease: rates of testing, treatment, and fractures. Osteoporos Int 22(6):1855\u20131862. \nhttps:\/\/doi.org\/10.1007\/s00198-010-1423-y","journal-title":"Osteoporos Int"},{"issue":"may22 1","key":"4314_CR7","doi-asserted-by":"publisher","first-page":"e3427","DOI":"10.1136\/bmj.e3427","volume":"344","author":"J Hippisley-Cox","year":"2012","unstructured":"Hippisley-Cox J, Coupland C (2012) Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study. BMJ 344(may22 1):e3427. \nhttps:\/\/doi.org\/10.1136\/bmj.e3427","journal-title":"BMJ"},{"issue":"6","key":"4314_CR8","doi-asserted-by":"publisher","first-page":"1288","DOI":"10.1016\/j.bone.2012.02.639","volume":"50","author":"EM Dennison","year":"2012","unstructured":"Dennison EM, Compston JE, Flahive J, Siris ES, Gehlbach SH, Adachi JD, Boonen S, Chapurlat R, Diez-Perez A, Anderson FA Jr, Hooven FH, LaCroix AZ, Lindsay R, Netelenbos JC, Pfeilschifter J, Rossini M, Roux C, Saag KG, Sambrook P, Silverman S, Watts NB, Greenspan SL, Premaor M, Cooper C (2012) Effect of co-morbidities on fracture risk: findings from the Global Longitudinal Study of Osteoporosis in Women (GLOW). Bone 50(6):1288\u20131293. \nhttps:\/\/doi.org\/10.1016\/j.bone.2012.02.639","journal-title":"Bone"},{"issue":"5","key":"4314_CR9","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1183\/09031936.05.00058204","volume":"25","author":"F Vries de","year":"2005","unstructured":"de Vries F, van Staa TP, Bracke MS, Cooper C, Leufkens HG, Lammers JW (2005) Severity of obstructive airway disease and risk of osteoporotic fracture. Eur Respir J 25(5):879\u2013884. \nhttps:\/\/doi.org\/10.1183\/09031936.05.00058204","journal-title":"Eur Respir J"},{"key":"4314_CR10","doi-asserted-by":"publisher","first-page":"637","DOI":"10.2147\/copd.s79638","volume":"11","author":"D Inoue","year":"2016","unstructured":"Inoue D, Watanabe R, Okazaki R (2016) COPD and osteoporosis: links, risks, and treatment challenges. Int J Chron Obstruct Pulmon Dis 11:637\u2013648. \nhttps:\/\/doi.org\/10.2147\/copd.s79638","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"issue":"6","key":"4314_CR11","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1007\/s00198-010-1421-0","volume":"22","author":"CS Ryan","year":"2011","unstructured":"Ryan CS, Petkov VI, Adler RA (2011) Osteoporosis in men: the value of laboratory testing. Osteoporos Int 22(6):1845\u20131853. \nhttps:\/\/doi.org\/10.1007\/s00198-010-1421-0","journal-title":"Osteoporos Int"},{"issue":"1","key":"4314_CR12","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1183\/09031936.50130408","volume":"34","author":"L Graat-Verboom","year":"2009","unstructured":"Graat-Verboom L, Wouters EF, Smeenk FW, van den Borne BE, Lunde R, Spruit MA (2009) Current status of research on osteoporosis in COPD: a systematic review. Eur Respir J 34(1):209\u2013218. \nhttps:\/\/doi.org\/10.1183\/09031936.50130408","journal-title":"Eur Respir J"},{"issue":"1","key":"4314_CR13","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1186\/1471-2466-12-26","volume":"12","author":"KM Schnell","year":"2012","unstructured":"Schnell KM, Weiss CO, Lee T, Krishnan JA, Leff B, Wolff JL, Boyd C (2012) The prevalence of clinically-relevant comorbid conditions in patients with COPD: a cross-sectional study using data from NHANES 1999-2008. BMC Pulm Med 12(1):26. \nhttps:\/\/doi.org\/10.1186\/1471-2466-12-26","journal-title":"BMC Pulm Med"},{"issue":"4","key":"4314_CR14","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1007\/s00774-014-0605-7","volume":"33","author":"R Watanabe","year":"2014","unstructured":"Watanabe R, Tanaka T, Aita K, Hagiya M, Homma T, Yokosuka K, Yamakawa H, Yarita T, Tai N, Hirano J, Inoue D, Okazaki R (2014) Osteoporosis is highly prevalent in Japanese males with chronic obstructive pulmonary disease and is associated with deteriorated pulmonary function. J Bone Miner Metab 33(4):392\u2013400. \nhttps:\/\/doi.org\/10.1007\/s00774-014-0605-7","journal-title":"J Bone Miner Metab"},{"issue":"3","key":"4314_CR15","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1002\/jbmr.257","volume":"26","author":"L Graat-Verboom","year":"2011","unstructured":"Graat-Verboom L, van den Borne BE, Smeenk FW, Spruit MA, Wouters EF (2011) Osteoporosis in COPD outpatients based on bone mineral density and vertebral fractures. J Bone Miner Res 26(3):561\u2013568. \nhttps:\/\/doi.org\/10.1002\/jbmr.257","journal-title":"J Bone Miner Res"},{"issue":"4","key":"4314_CR16","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1007\/s00198-007-0543-5","volume":"19","author":"JA Kanis","year":"2008","unstructured":"Kanis JA, Johnell O, Oden A, Johansson H, McCloskey E (2008) FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int 19(4):385\u2013397. \nhttps:\/\/doi.org\/10.1007\/s00198-007-0543-5","journal-title":"Osteoporos Int"},{"issue":"6","key":"4314_CR17","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1111\/joim.12369","volume":"277","author":"M Lorentzon","year":"2015","unstructured":"Lorentzon M, Cummings SR (2015) Osteoporosis: the evolution of a diagnosis. J Intern Med 277(6):650\u2013661. \nhttps:\/\/doi.org\/10.1111\/joim.12369","journal-title":"J Intern Med"},{"issue":"6","key":"4314_CR18","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1001\/jama.285.6.785","volume":"285","author":"NIH Consensus Development Panel on Osteoporosis Prevention D, and Therapy","year":"2001","unstructured":"NIH Consensus Development Panel on Osteoporosis Prevention D, and Therapy (2001) Osteoporosis prevention, diagnosis, and therapy. JAMA 285(6):785\u2013795. \nhttps:\/\/doi.org\/10.1001\/jama.285.6.785","journal-title":"JAMA"},{"issue":"9","key":"4314_CR19","doi-asserted-by":"publisher","first-page":"1931","DOI":"10.1002\/jbmr.88","volume":"25","author":"CA Kulak","year":"2010","unstructured":"Kulak CA, Borba VC, Jorgetti V, Dos Reis LM, Liu XS, Kimmel DB, Kulak J Jr, Rabelo LM, Zhou H, Guo XE, Bilezikian JP, Boguszewski CL, Dempster DW (2010) Skeletal microstructural abnormalities in postmenopausal women with chronic obstructive pulmonary disease. J Bone Miner Res 25(9):1931\u20131940. \nhttps:\/\/doi.org\/10.1002\/jbmr.88","journal-title":"J Bone Miner Res"},{"issue":"3","key":"4314_CR20","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/jbmr.2176","volume":"29","author":"BC Silva","year":"2014","unstructured":"Silva BC, Leslie WD, Resch H, Lamy O, Lesnyak O, Binkley N, McCloskey EV, Kanis JA, Bilezikian JP (2014) Trabecular bone score: a noninvasive analytical method based upon the DXA image. J Bone Miner Res 29(3):518\u2013530. \nhttps:\/\/doi.org\/10.1002\/jbmr.2176","journal-title":"J Bone Miner Res"},{"issue":"11","key":"4314_CR21","doi-asserted-by":"publisher","first-page":"2762","DOI":"10.1002\/jbmr.499","volume":"26","author":"D Hans","year":"2011","unstructured":"Hans D, Goertzen AL, Krieg MA, Leslie WD (2011) Bone microarchitecture assessed by TBS predicts osteoporotic fractures independent of bone density: the Manitoba study. J Bone Miner Res 26(11):2762\u20132769. \nhttps:\/\/doi.org\/10.1002\/jbmr.499","journal-title":"J Bone Miner Res"},{"issue":"3","key":"4314_CR22","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.jocd.2013.01.006","volume":"16","author":"WD Leslie","year":"2013","unstructured":"Leslie WD, Krieg MA, Hans D (2013) Clinical factors associated with trabecular bone score. J Clin Densitom 16(3):374\u2013379. \nhttps:\/\/doi.org\/10.1016\/j.jocd.2013.01.006","journal-title":"J Clin Densitom"},{"issue":"9","key":"4314_CR23","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1002\/jbmr.5650080915","volume":"8","author":"HK Genant","year":"1993","unstructured":"Genant HK, CY W, van Kuijk C, Nevitt MC (1993) Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res 8(9):1137\u20131148. \nhttps:\/\/doi.org\/10.1002\/jbmr.5650080915","journal-title":"J Bone Miner Res"},{"issue":"6","key":"4314_CR24","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1007\/BF01622200","volume":"4","author":"JA Kanis","year":"1994","unstructured":"Kanis JA (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis: synopsis of a WHO report. WHO Study Group. Osteoporos Int 4(6):368\u2013381. \nhttps:\/\/doi.org\/10.1007\/BF01622200","journal-title":"Osteoporos Int"},{"issue":"5","key":"4314_CR25","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1002\/jbmr.2734","volume":"31","author":"EV McCloskey","year":"2016","unstructured":"McCloskey EV, Oden A, Harvey NC, Leslie WD, Hans D, Johansson H, Barkmann R, Boutroy S, Brown J, Chapurlat R, Elders PJ, Fujita Y, Gluer CC, Goltzman D, Iki M, Karlsson M, Kindmark A, Kotowicz M, Kurumatani N, Kwok T, Lamy O, Leung J, Lippuner K, Ljunggren O, Lorentzon M, Mellstrom D, Merlijn T, Oei L, Ohlsson C, Pasco JA, Rivadeneira F, Rosengren B, Sornay-Rendu E, Szulc P, Tamaki J, Kanis JA (2016) A meta-analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX. J Bone Miner Res 31(5):940\u2013948. \nhttps:\/\/doi.org\/10.1002\/jbmr.2734","journal-title":"J Bone Miner Res"},{"issue":"2","key":"4314_CR26","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1007\/s12020-014-0280-4","volume":"47","author":"FM Ulivieri","year":"2014","unstructured":"Ulivieri FM, Silva BC, Sardanelli F, Hans D, Bilezikian JP, Caudarella R (2014) Utility of the trabecular bone score (TBS) in secondary osteoporosis. Endocrine 47(2):435\u2013448. \nhttps:\/\/doi.org\/10.1007\/s12020-014-0280-4","journal-title":"Endocrine"},{"issue":"1","key":"4314_CR27","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-12-157","volume":"12","author":"P Bai","year":"2011","unstructured":"Bai P, Sun Y, Jin J, Hou J, Li R, Zhang Q, Wang Y (2011) Disturbance of the OPG\/RANK\/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis. Respir Res 12(1):157. \nhttps:\/\/doi.org\/10.1186\/1465-9921-12-157","journal-title":"Respir Res"},{"issue":"1","key":"4314_CR28","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1007\/s12020-011-9583-x","volume":"42","author":"B Liang","year":"2012","unstructured":"Liang B, Feng Y (2012) The association of low bone mineral density with systemic inflammation in clinically stable COPD. Endocrine 42(1):190\u2013195. \nhttps:\/\/doi.org\/10.1007\/s12020-011-9583-x","journal-title":"Endocrine"},{"issue":"1","key":"4314_CR29","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s00198-014-2826-y","volume":"26","author":"W ZJ","year":"2015","unstructured":"ZJ W, He JL, Wei RQ, Liu B, Lin X, Guan J, Lan YB (2015) C-reactive protein and risk of fracture: a systematic review and dose-response meta-analysis of prospective cohort studies. Osteoporos Int 26(1):49\u201357. \nhttps:\/\/doi.org\/10.1007\/s00198-014-2826-y","journal-title":"Osteoporos Int"},{"issue":"2","key":"4314_CR30","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1002\/jbmr.2037","volume":"29","author":"AL Eriksson","year":"2014","unstructured":"Eriksson AL, Moverare-Skrtic S, Ljunggren O, Karlsson M, Mellstrom D, Ohlsson C (2014) High-sensitivity CRP is an independent risk factor for all fractures and vertebral fractures in elderly men: the MrOS Sweden study. J Bone Miner Res 29(2):418\u2013423. \nhttps:\/\/doi.org\/10.1002\/jbmr.2037","journal-title":"J Bone Miner Res"},{"issue":"1","key":"4314_CR31","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.atherosclerosis.2004.08.014","volume":"178","author":"H Tomiyama","year":"2005","unstructured":"Tomiyama H, Okazaki R, Koji Y, Usui Y, Hayashi T, Hori S, Yamashina A (2005) Elevated C-reactive protein: a common marker for atherosclerotic cardiovascular risk and subclinical stages of pulmonary dysfunction and osteopenia in a healthy population. Atherosclerosis 178(1):187\u2013192. \nhttps:\/\/doi.org\/10.1016\/j.atherosclerosis.2004.08.014","journal-title":"Atherosclerosis"},{"issue":"1","key":"4314_CR32","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/j.bone.2013.05.009","volume":"56","author":"S Ahmadi-Abhari","year":"2013","unstructured":"Ahmadi-Abhari S, Luben RN, Wareham NJ, Khaw KT (2013) C-reactive protein and fracture risk: European prospective investigation into Cancer Norfolk Study. Bone 56(1):67\u201372. \nhttps:\/\/doi.org\/10.1016\/j.bone.2013.05.009","journal-title":"Bone"},{"issue":"2","key":"4314_CR33","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1007\/s00198-014-2951-7","volume":"26","author":"S Berglundh","year":"2015","unstructured":"Berglundh S, Malmgren L, Luthman H, McGuigan F, Akesson K (2015) C-reactive protein, bone loss, fracture, and mortality in elderly women: a longitudinal study in the OPRA cohort. Osteoporos Int 26(2):727\u2013735. \nhttps:\/\/doi.org\/10.1007\/s00198-014-2951-7","journal-title":"Osteoporos Int"},{"issue":"7","key":"4314_CR34","doi-asserted-by":"publisher","first-page":"1688","DOI":"10.1002\/jbmr.1915","volume":"28","author":"S Ishii","year":"2013","unstructured":"Ishii S, Cauley JA, Greendale GA, Crandall CJ, Danielson ME, Ouchi Y, Karlamangla AS (2013) C-reactive protein, bone strength, and nine-year fracture risk: data from the Study of Women\u2019s Health Across the Nation (SWAN). J Bone Miner Res 28(7):1688\u20131698. \nhttps:\/\/doi.org\/10.1002\/jbmr.1915","journal-title":"J Bone Miner Res"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-017-4314-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-017-4314-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-017-4314-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,2]],"date-time":"2018-03-02T21:53:08Z","timestamp":1520027588000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-017-4314-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,22]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["4314"],"URL":"https:\/\/doi.org\/10.1007\/s00198-017-4314-7","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,22]]}}}