{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T08:07:34Z","timestamp":1771488454914,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T00:00:00Z","timestamp":1575244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T00:00:00Z","timestamp":1575244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1007\/s00198-019-05227-9","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T11:21:32Z","timestamp":1575285692000},"page":"995-1000","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Intravenous bisphosphonate therapy in children with spinal muscular atrophy"],"prefix":"10.1007","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8996-8760","authenticated-orcid":false,"given":"N.","family":"Nasomyont","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.N.","family":"Hornung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8309-6321","authenticated-orcid":false,"given":"H.","family":"Wasserman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,12,2]]},"reference":[{"issue":"20","key":"5227_CR1","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1212\/WNL.0000000000006502","volume":"91","author":"D Michelson","year":"2018","unstructured":"Michelson D, Ciafaloni E, Ashwal S, Lewis E, Narayanaswami P, Oskoui M et al (2018) Evidence in focus: nusinersen use in spinal muscular atrophy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 91(20):923\u2013933","journal-title":"Neurology."},{"key":"5227_CR2","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.bone.2015.05.039","volume":"79","author":"S Vai","year":"2015","unstructured":"Vai S, Bianchi ML, Moroni I, Mastella C, Broggi F, Morandi L, Arnoldi MT, Bussolino C, Baranello G (2015) Bone and spinal muscular atrophy. Bone. 79:116\u2013120","journal-title":"Bone."},{"issue":"1","key":"5227_CR3","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1002\/path.2566","volume":"219","author":"S Shanmugarajan","year":"2009","unstructured":"Shanmugarajan S, Tsuruga E, Swoboda KJ, Maria BL, Ries WL, Reddy SV (2009) Bone loss in survival motor neuron (Smn(-\/-) SMN2) genetic mouse model of spinal muscular atrophy. J Pathol 219(1):52\u201360","journal-title":"J Pathol"},{"issue":"4","key":"5227_CR4","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1016\/j.nmd.2017.01.019","volume":"27","author":"HM Wasserman","year":"2017","unstructured":"Wasserman HM, Hornung LN, Stenger PJ, Rutter MM, Wong BL, Rybalsky I, Khoury JC, Kalkwarf HJ (2017) Low bone mineral density and fractures are highly prevalent in pediatric patients with spinal muscular atrophy regardless of disease severity. Neuromuscul Disord 27(4):331\u2013337","journal-title":"Neuromuscul Disord"},{"issue":"4","key":"5227_CR5","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1080\/165019701750300609","volume":"33","author":"P Vestergaard","year":"2001","unstructured":"Vestergaard P, Glerup H, Steffensen BF, Rejnmark L, Rahbek J, Moseklide L (2001) Fracture risk in patients with muscular dystrophy and spinal muscular atrophy. J Rehabil Med 33(4):150\u2013155","journal-title":"J Rehabil Med"},{"issue":"6","key":"5227_CR6","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1007\/s00402-010-1096-1","volume":"130","author":"A Fujak","year":"2010","unstructured":"Fujak A, Kopschina C, Forst R, Gras F, Mueller LA, Forst J (2010) Fractures in proximal spinal muscular atrophy. Arch Orthop Trauma Surg 130(6):775\u2013780","journal-title":"Arch Orthop Trauma Surg"},{"issue":"1","key":"5227_CR7","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1097\/CND.0b013e318183e0fa","volume":"10","author":"IA Khatri","year":"2008","unstructured":"Khatri IA, Chaudhry US, Seikaly MG, Browne RH, Iannaccone ST (2008) Low bone mineral density in spinal muscular atrophy. J Clin Neuromuscul Dis 10(1):11\u201317","journal-title":"J Clin Neuromuscul Dis"},{"issue":"6","key":"5227_CR8","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1055\/s-2004-830366","volume":"35","author":"M Kinali","year":"2004","unstructured":"Kinali M, Banks LM, Mercuri E, Manzur AY, Muntoni F (2004) Bone mineral density in a paediatric spinal muscular atrophy population. Neuropediatrics. 35(6):325\u2013328","journal-title":"Neuropediatrics."},{"issue":"2","key":"5227_CR9","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.nmd.2017.11.005","volume":"28","author":"E Mercuri","year":"2018","unstructured":"Mercuri E, Finkel RS, Muntoni F, Wirth B, Montes J, Main M et al (2018) Diagnosis and management of spinal muscular atrophy: Part 1: Recommendations for diagnosis, rehabilitation, orthopedic and nutritional care. Neuromuscul Disord 28(2):103\u2013115","journal-title":"Neuromuscul Disord"},{"issue":"2","key":"5227_CR10","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.jocd.2014.01.007","volume":"17","author":"CM Gordon","year":"2014","unstructured":"Gordon CM, Leonard MB, Zemel BS (2014) International Society for Clinical D. 2013 Pediatric Position Development Conference: executive summary and reflections. J Clin Densitom 17(2):219\u2013224","journal-title":"J Clin Densitom"},{"issue":"Suppl 1","key":"5227_CR11","first-page":"584","volume":"5","author":"L Ardeshirpour","year":"2007","unstructured":"Ardeshirpour L, Cole DE, Carpenter TO (2007) Evaluation of bone and mineral disorders. Pediatr Endocrinol Rev 5(Suppl 1):584\u2013598","journal-title":"Pediatr Endocrinol Rev"},{"issue":"2","key":"5227_CR12","doi-asserted-by":"publisher","first-page":"439","DOI":"10.2214\/ajr.178.2.1780439","volume":"178","author":"RC Henderson","year":"2002","unstructured":"Henderson RC, Lark RK, Newman JE, Kecskemthy H, Fung EB, Renner JB, Harcke HT (2002) Pediatric reference data for dual X-ray absorptiometric measures of normal bone density in the distal femur. AJR Am J Roentgenol 178(2):439\u2013443","journal-title":"AJR Am J Roentgenol"},{"issue":"2","key":"5227_CR13","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.jocd.2009.01.005","volume":"12","author":"BS Zemel","year":"2009","unstructured":"Zemel BS, Stallings VA, Leonard MB, Paulhamus DR, Kecskemethy HH, Harcke HT, Henderson RC (2009) Revised pediatric reference data for the lateral distal femur measured by Hologic Discovery\/Delphi dual-energy X-ray absorptiometry. J Clin Densitom 12(2):207\u2013218","journal-title":"J Clin Densitom"},{"issue":"9","key":"5227_CR14","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1111\/j.1469-8749.2010.03676.x","volume":"52","author":"SJ Bachrach","year":"2010","unstructured":"Bachrach SJ, Kecskemethy HH, Harcke HT, Hossain J (2010) Decreased fracture incidence after 1 year of pamidronate treatment in children with spastic quadriplegic cerebral palsy. Dev Med Child Neurol 52(9):837\u2013842","journal-title":"Dev Med Child Neurol"},{"issue":"2","key":"5227_CR15","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1097\/BPO.0000000000000421","volume":"36","author":"JP Sees","year":"2016","unstructured":"Sees JP, Sitoula P, Dabney K, Holmes L Jr, Rogers KJ, Kecskemethy HH et al (2016) Pamidronate treatment to prevent reoccurring fractures in children with cerebral palsy. J Pediatr Orthop 36(2):193\u2013197","journal-title":"J Pediatr Orthop"},{"issue":"11","key":"5227_CR16","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1016\/j.nmd.2012.04.008","volume":"22","author":"KE Poruk","year":"2012","unstructured":"Poruk KE, Davis RH, Smart AL, Chisum BS, Lasalle BA, Chan GM, Gill G, Reyna SP, Swoboda KJ (2012) Observational study of caloric and nutrient intake, bone density, and body composition in infants and children with spinal muscular atrophy type I. Neuromuscul Disord 22(11):966\u2013973","journal-title":"Neuromuscul Disord"},{"issue":"9","key":"5227_CR17","doi-asserted-by":"publisher","first-page":"918","DOI":"10.1111\/dmcn.13196","volume":"58","author":"S Ozel","year":"2016","unstructured":"Ozel S, Switzer L, Macintosh A, Fehlings D (2016) Informing evidence-based clinical practice guidelines for children with cerebral palsy at risk of osteoporosis: an update. Dev Med Child Neurol 58(9):918\u2013923","journal-title":"Dev Med Child Neurol"},{"key":"5227_CR18","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1016\/j.bone.2019.01.003","volume":"121","author":"N Nasomyont","year":"2019","unstructured":"Nasomyont N, Hornung LN, Gordon CM, Wasserman H (2019) Outcomes following intravenous bisphosphonate infusion in pediatric patients: a 7-year retrospective chart review. Bone. 121:60\u201367","journal-title":"Bone."},{"issue":"11","key":"5227_CR19","doi-asserted-by":"publisher","first-page":"2267","DOI":"10.1002\/jbmr.253","volume":"25","author":"E Shane","year":"2010","unstructured":"Shane E, Burr D, Ebeling PR, Abrahamsen B, Adler RA, Brown TD et al (2010) Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research. J Bone Miner Res 25(11):2267\u20132294","journal-title":"J Bone Miner Res"},{"issue":"1","key":"5227_CR20","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1159\/000447425","volume":"87","author":"AM Boyce","year":"2017","unstructured":"Boyce AM, Collins MT, Tosi LL, Gafni RI (2017) A subtrochanteric femoral stress fracture following bisphosphonate treatment in an adolescent girl. Horm Res Paediatr 87(1):69\u201372","journal-title":"Horm Res Paediatr"},{"issue":"5","key":"5227_CR21","doi-asserted-by":"publisher","first-page":"1034","DOI":"10.1002\/jbmr.3071","volume":"32","author":"P Trejo","year":"2017","unstructured":"Trejo P, Fassier F, Glorieux FH, Rauch F (2017) Diaphyseal femur fractures in osteogenesis imperfecta: characteristics and relationship with bisphosphonate treatment. J Bone Miner Res 32(5):1034\u20131039","journal-title":"J Bone Miner Res"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-019-05227-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00198-019-05227-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-019-05227-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,11,30]],"date-time":"2020-11-30T19:49:00Z","timestamp":1606765740000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00198-019-05227-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,2]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["5227"],"URL":"https:\/\/doi.org\/10.1007\/s00198-019-05227-9","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,2]]},"assertion":[{"value":"2 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 November 2019","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 December 2019","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The study was approved by the Institutional Review Board.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}