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This study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendment. All participants provided written informed consent at the time of recruitment.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"None.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}