{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T03:06:50Z","timestamp":1791688010982,"version":"4.3.4"},"reference-count":58,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T00:00:00Z","timestamp":1743724800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UM1TR004528"],"award-info":[{"award-number":["UM1TR004528"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s00198-025-07473-6","type":"journal-article","created":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T14:12:44Z","timestamp":1743862364000},"page":"907-916","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Osteoporosis is not associated with increased reoperation or fracture risk three years after total ankle arthroplasty: a retrospective cohort study"],"prefix":"10.1007","volume":"36","author":[{"given":"Anthony N.","family":"Baumann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra N.","family":"Krez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Trager","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9135-0484","authenticated-orcid":false,"given":"Omkar S.","family":"Anaspure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kempland C.","family":"Walley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihir","family":"Surapaneni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert T.","family":"Anastasio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,4]]},"reference":[{"key":"7473_CR1","doi-asserted-by":"crossref","unstructured":"Easley ME, Adams SB, Hembree WC, DeOrio JK. 2011. Results of total ankle arthroplasty. Journal of Bone and Joint Surgery 93(15).","DOI":"10.2106\/JBJS.J.00126"},{"key":"7473_CR2","doi-asserted-by":"crossref","unstructured":"Henry JK, Shaffrey I, Cororaton AD, et al. 2024. Implant choice may reduce the risk of early mechanical failure in total ankle replacement. Journal of Bone and Joint Surgery .","DOI":"10.2106\/JBJS.23.00933"},{"key":"7473_CR3","doi-asserted-by":"crossref","unstructured":"Karzon AL, Kadakia RJ, Coleman MM, et al. 2022. The rise of total ankle arthroplasty use: a database analysis describing case volumes and incidence trends in the United States between 2009 and 2019. Foot Ankle Int 43(11).","DOI":"10.1177\/10711007221119148"},{"key":"7473_CR4","doi-asserted-by":"crossref","unstructured":"Rippstein PF, Huber M, Coetzee JC, Naal FD. 2011. Total ankle replacement with use of a new three-component implant. Journal of Bone and Joint Surgery 93(15).","DOI":"10.2106\/JBJS.J.00913"},{"key":"7473_CR5","unstructured":"Van Alexander Heuvel DEN, Van Bouwel S, Dereymaeker G. 2010. Total ankle replacement design evolution and results. Acta Orthop Belg 76(2)."},{"key":"7473_CR6","doi-asserted-by":"crossref","unstructured":"Haddad SL, Coetzee JC, Estok R, et al. 2007. Intermediate and long-term outcomes of total ankle arthroplasty and ankle arthrodesis: a systematic review of the literature. Journal of Bone and Joint Surgery 89(9):1899\u20131905 [cited 2023 Jun 22].","DOI":"10.2106\/JBJS.F.01149"},{"key":"7473_CR7","doi-asserted-by":"crossref","unstructured":"Chopra S, Rouhani H, Assal M, et al. 2014. Outcome of unilateral ankle arthrodesis and total ankle replacement in terms of bilateral gait mechanics. Journal of Orthopaedic Research 32(3).","DOI":"10.1002\/jor.22520"},{"key":"7473_CR8","doi-asserted-by":"crossref","unstructured":"Saltzman CL, Kadoko RG, Suh JS. 2010. Treatment of isolated ankle osteoarthritis with arthrodesis or the total ankle replacement: a comparison of early outcomes. Clin Orthop Surg 2(1).","DOI":"10.4055\/cios.2010.2.1.1"},{"key":"7473_CR9","doi-asserted-by":"crossref","unstructured":"Younger ASE, Wing KJ, Glazebrook M, et al. 2015. Patient expectation and satisfaction as measures of operative outcome in end-stage ankle arthritis: a prospective cohort study of total ankle replacement versus ankle fusion. Foot Ankle Int 36(2).","DOI":"10.1177\/1071100714565902"},{"key":"7473_CR10","doi-asserted-by":"crossref","unstructured":"Randsborg PH, Jiang H, Mao J, et al. 2022. Two-year revision rates in total ankle replacement versus ankle arthrodesis: a population-based propensity-score-matched comparison from New York State and California. JBJS Open Access 7(2).","DOI":"10.2106\/JBJS.OA.21.00136"},{"key":"7473_CR11","doi-asserted-by":"crossref","unstructured":"Cody EA, Taylor MA, Nunley JA, et al. 2019. Increased early revision rate with the INFINITY total ankle prosthesis. Foot Ankle Int 40(1).","DOI":"10.1177\/1071100718794933"},{"key":"7473_CR12","doi-asserted-by":"crossref","unstructured":"Saito GH, Sanders AE, de Cesar Netto C, et al. 2018. Short-term complications, reoperations, and radiographic outcomes of a new fixed-bearing total ankle arthroplasty. Foot Ankle Int 39(7).","DOI":"10.1177\/1071100718764107"},{"key":"7473_CR13","doi-asserted-by":"crossref","unstructured":"Zaidi R, Cro S, Gurusamy K, et al. 2013. The outcome of total ankle replacement: a systematic review and meta-analysis. Bone and Joint Journal 95 B(11).","DOI":"10.1302\/0301-620X.95B11.31633"},{"key":"7473_CR14","doi-asserted-by":"crossref","unstructured":"Lachman JR, Ramos JA, Adams SB, et al. 2019. Patient-reported outcomes before and after primary and revision total ankle arthroplasty. Foot Ankle Int 40(1).","DOI":"10.1177\/1071100718794956"},{"key":"7473_CR15","doi-asserted-by":"crossref","unstructured":"Glazebrook MA, Arsenault K, Dunbar M. 2009. Evidence-based classification of complications in total ankle arthroplasty. Foot Ankle Int 30(10).","DOI":"10.3113\/FAI.2009.0945"},{"key":"7473_CR16","doi-asserted-by":"crossref","unstructured":"Und\u00e9n A, Jehpsson L, Kamrad I, et al. 2020. Better implant survival with modern ankle prosthetic designs: 1,226 total ankle prostheses followed for up to 20 years in the Swedish Ankle Registry. Acta Orthop 91(2).","DOI":"10.1080\/17453674.2019.1709312"},{"key":"7473_CR17","doi-asserted-by":"crossref","unstructured":"Varga C, V\u00e1ncsa S, Ag\u00f3cs G, et al. 2023. Obesity and ankle prosthesis revision: a systematic review and meta-analysis. Foot Ankle Int 44(12).","DOI":"10.1177\/10711007231201158"},{"key":"7473_CR18","doi-asserted-by":"crossref","unstructured":"Hermus JPS, van Kuijk SMJ, Spekenbrink-Spooren A, et al. 2022. Risk factors for total ankle arthroplasty failure: a Dutch Arthroplasty Register study. Foot and Ankle Surgery 28(7).","DOI":"10.1016\/j.fas.2021.12.001"},{"key":"7473_CR19","doi-asserted-by":"crossref","unstructured":"Escudero MI, Le V, Barahona M, et al. 2019. Total ankle arthroplasty survival and risk factors for failure. Foot Ankle Int 40(9).","DOI":"10.1177\/1071100719849084"},{"key":"7473_CR20","doi-asserted-by":"crossref","unstructured":"Jennison T, Ukoumunne OC, Lamb S, et al. 2023. Risk factors for failure of total ankle replacements: a data linkage study using the National Joint Registry and NHS Digital. Foot Ankle Int 44(7).","DOI":"10.1177\/10711007231176512"},{"key":"7473_CR21","doi-asserted-by":"crossref","unstructured":"Arshad Z, Haq II, Bhatia M. 2023. Patient-related risk factors associated with poorer outcomes following total ankle arthroplasty. Bone and Joint Journal 105 B(9).","DOI":"10.1302\/0301-620X.105B9.BJJ-2023-0052.R1"},{"key":"7473_CR22","doi-asserted-by":"crossref","unstructured":"Nixon M, Taylor G, Sheldon P, et al. 2007. Does bone quality predict loosening of cemented total hip replacements? Journal of Bone and Joint Surgery - Series B 89(10).","DOI":"10.1302\/0301-620X.89B10.19038"},{"key":"7473_CR23","doi-asserted-by":"crossref","unstructured":"Klemt C, Yeo I, Cohen-Levy WB, et al. 2022. Artificial neural networks can predict early failure of cementless total hip arthroplasty in patients with osteoporosis. Journal of the American Academy of Orthopaedic Surgeons 30(10).","DOI":"10.5435\/JAAOS-D-21-00775"},{"key":"7473_CR24","doi-asserted-by":"crossref","unstructured":"Petersen MM, Nielsen PT, Lebech A, et al. 1999. Preoperative bone mineral density of the proximal tibia and migration of the tibial component after uncemented total knee arthroplasty. Journal of Arthroplasty 14(1).","DOI":"10.1016\/S0883-5403(99)90206-1"},{"key":"7473_CR25","doi-asserted-by":"crossref","unstructured":"Thillemann TM, Pedersen AB, Mehnert F, et al. 2010. Postoperative use of bisphosphonates and risk of revision after primary total hip arthroplasty: a nationwide population-based study. Bone 46(4).","DOI":"10.1016\/j.bone.2010.01.377"},{"key":"7473_CR26","doi-asserted-by":"crossref","unstructured":"Chee A, \u00c7eliker P, Basedow K, et al. 2023. A call to \u201cown the bone\u201d: osteoporosis is a predictor for adverse two-year outcomes following total hip and knee arthroplasty. European Journal of Orthopaedic Surgery and Traumatology 33(7).","DOI":"10.1007\/s00590-023-03499-w"},{"key":"7473_CR27","doi-asserted-by":"crossref","unstructured":"Gundry M, Hopkins S, Knapp K. 2017. A review on bone mineral density loss in total knee replacements leading to increased fracture risk. Clin Rev Bone Miner Metab 15(4).","DOI":"10.1007\/s12018-017-9238-4"},{"key":"7473_CR28","doi-asserted-by":"crossref","unstructured":"Cody EA, Lachman JR, Gausden EB, et al. 2019. Lower bone density on preoperative computed tomography predicts periprosthetic fracture risk in total ankle arthroplasty. Foot Ankle Int 40(1).","DOI":"10.1177\/1071100718799102"},{"key":"7473_CR29","doi-asserted-by":"crossref","unstructured":"Salari N, Ghasemi H, Mohammadi L, et al. 2021. The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis. J Orthop Surg Res 16(1).","DOI":"10.1186\/s13018-021-02772-0"},{"key":"7473_CR30","doi-asserted-by":"crossref","unstructured":"Looker AC, Sarafrazi Isfahani N, Fan B, Shepherd JA. 2017. Trends in osteoporosis and low bone mass in older US adults, 2005\u20132006 through 2013\u20132014. Osteoporosis International 28(6).","DOI":"10.1007\/s00198-017-3996-1"},{"key":"7473_CR31","doi-asserted-by":"crossref","unstructured":"Anderson KD, Ko FC, Virdi AS, et al. 2020. Biomechanics of implant fixation in osteoporotic bone. Curr Osteoporos Rep 18(5).","DOI":"10.1007\/s11914-020-00614-2"},{"key":"7473_CR32","doi-asserted-by":"crossref","unstructured":"Maier GS, Kolbow K, Lazovic D, Maus U. 2016. The importance of bone mineral density in hip arthroplasty: results of a survey asking orthopaedic surgeons about their opinions and attitudes concerning osteoporosis and hip arthroplasty. Adv Orthop 2016.","DOI":"10.1155\/2016\/8079354"},{"key":"7473_CR33","doi-asserted-by":"crossref","unstructured":"Legnar M, Daumke P, Hesser J, et al. 2022. Natural language processing in diagnostic texts from nephropathology. Diagnostics 12(7).","DOI":"10.3390\/diagnostics12071726"},{"key":"7473_CR34","doi-asserted-by":"crossref","unstructured":"Daumke P, Heitmann KU, Heckmann S, et al. 2019. Clinical text mining on FHIR. In: Studies in Health Technology and Informatics. .","DOI":"10.3233\/SHTI190188"},{"key":"7473_CR35","doi-asserted-by":"crossref","unstructured":"Pokora RM, Le Cornet L, Daumke P, et al. 2020. Validation of semantic analyses of unstructured medical data for research purposes. Gesundheitswesen, Supplement 82.","DOI":"10.1055\/a-1100-1630"},{"key":"7473_CR36","doi-asserted-by":"crossref","unstructured":"Lee JW, Im WY, Song SY, et al. 2021. Analysis of early failure rate and its risk factor with 2157 total ankle replacements. Sci Rep 11(1).","DOI":"10.1038\/s41598-021-81576-y"},{"key":"7473_CR37","doi-asserted-by":"crossref","unstructured":"Conti MS, Savenkov O, Ellis SJ. 2019. Association of peripheral vascular disease with complications after total ankle arthroplasty. Foot Ankle Orthop 4(2).","DOI":"10.1177\/2473011419843379"},{"issue":"17","key":"7473_CR38","doi-asserted-by":"publisher","first-page":"1554","DOI":"10.2106\/JBJS.21.01240","volume":"104","author":"BA Jamjoom","year":"2022","unstructured":"Jamjoom BA, Siddiqui BM, Salem H et al (2022) Clinical and radiographic outcomes of revision total ankle arthroplasty using the INBONE II prosthesis. J Bone Joint Surg Am 104(17):1554\u20131562","journal-title":"J Bone Joint Surg Am"},{"issue":"4","key":"7473_CR39","doi-asserted-by":"publisher","first-page":"948","DOI":"10.1016\/j.arth.2023.10.045","volume":"39","author":"AB Harris","year":"2024","unstructured":"Harris AB, Lantieri MA, Agarwal AR et al (2024) Osteoporosis and total knee arthroplasty: higher 5-year implant-related complications. J Arthroplasty 39(4):948-953.e1","journal-title":"J Arthroplasty"},{"key":"7473_CR40","doi-asserted-by":"crossref","unstructured":"Linacre JM. 2022. R Statistics: survey and review of packages for the estimation of Rasch models. Int J Med Educ 13.","DOI":"10.5116\/ijme.629d.d88f"},{"key":"7473_CR41","doi-asserted-by":"crossref","unstructured":"Wickham H. 2011. ggplot2. Wiley Interdiscip Rev Comput Stat 3(2).","DOI":"10.1002\/wics.147"},{"key":"7473_CR42","doi-asserted-by":"crossref","unstructured":"Demetracopoulos CA, Adams SB, Queen RM, et al. 2015. Effect of age on outcomes in total ankle arthroplasty. Foot Ankle Int 36(8).","DOI":"10.1177\/1071100715579717"},{"key":"7473_CR43","doi-asserted-by":"crossref","unstructured":"Stadler C, Luger M, Stevoska S, et al. 2022. High reoperation rate in mobile\u2010bearing total ankle arthroplasty in young patients. Medicina (Lithuania) 58(2).","DOI":"10.3390\/medicina58020288"},{"key":"7473_CR44","doi-asserted-by":"crossref","unstructured":"Ahmad A, Crawford CH, Glassman SD, et al. 2023. Correlation between bone density measurements on CT or MRI versus DEXA scan: a systematic review. North American Spine Society Journal 14.","DOI":"10.1016\/j.xnsj.2023.100204"},{"key":"7473_CR45","doi-asserted-by":"crossref","unstructured":"Yaprak G, Gemici C, Seseogullari OO, et al. 2020. CT derived Hounsfield unit: an easy way to determine osteoporosis and radiation related fracture risk in irradiated patients. Front Oncol 10.","DOI":"10.3389\/fonc.2020.00742"},{"key":"7473_CR46","doi-asserted-by":"crossref","unstructured":"Shigehara K, Izumi K, Kadono Y, Mizokami A. 2021. Testosterone and bone health in men: a narrative review. J Clin Med 10(3).","DOI":"10.3390\/jcm10030530"},{"issue":"4","key":"7473_CR47","doi-asserted-by":"publisher","first-page":"750","DOI":"10.5534\/wjmh.200099","volume":"39","author":"M De Martinis","year":"2021","unstructured":"De Martinis M, Sirufo MM, Polsinelli M et al (2021) Gender differences in osteoporosis: a single-center observational study. World J Mens Health 39(4):750\u2013759","journal-title":"World J Mens Health"},{"issue":"4","key":"7473_CR48","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s00223-001-1043-9","volume":"69","author":"LJ Melton","year":"2001","unstructured":"Melton LJ (2001) The prevalence of osteoporosis: gender and racial comparison. Calcif Tissue Int 69(4):179\u2013181","journal-title":"Calcif Tissue Int"},{"key":"7473_CR49","doi-asserted-by":"crossref","unstructured":"Wright NC, Looker AC, Saag KG, et al. 2014. The recent prevalence of osteoporosis and low bone mass in the United States based on bone mineral density at the femoral neck or lumbar spine. Journal of Bone and Mineral Research 29(11).","DOI":"10.1002\/jbmr.2269"},{"key":"7473_CR50","doi-asserted-by":"crossref","unstructured":"Lee RW, Volz RG, Sheridan DC. 1991. The role of fixation and bone quality on the mechanical stability of tibial knee components. In: Clinical Orthopaedics and Related Research. .","DOI":"10.1097\/00003086-199112000-00027"},{"key":"7473_CR51","doi-asserted-by":"crossref","unstructured":"Della Rocca GJ, Leung KS, Pape HC. 2011. Periprosthetic fractures: epidemiology and future projections. In: Journal of Orthopaedic Trauma. .","DOI":"10.1097\/BOT.0b013e31821b8c28"},{"key":"7473_CR52","doi-asserted-by":"crossref","unstructured":"Frenzel S, V\u00e9csei V, Negrin L. 2015. Periprosthetic femoral fractures\u2014incidence, classification problems and the proposal of a modified classification scheme. Int Orthop 39(10).","DOI":"10.1007\/s00264-015-2967-4"},{"key":"7473_CR53","doi-asserted-by":"crossref","unstructured":"Harris AB, Lantieri MA, Agarwal AR, et al. 2024. Osteoporosis and total knee arthroplasty: higher 5-year implant-related complications. Journal of Arthroplasty 39(4).","DOI":"10.1016\/j.arth.2023.10.045"},{"key":"7473_CR54","doi-asserted-by":"crossref","unstructured":"So E, Rushing CJ, Prissel MA, Berlet GC. 2021. Bone mineral density testing in patients undergoing total ankle arthroplasty: should we pay more attention to the bone quality? Journal of Foot and Ankle Surgery 60(2).","DOI":"10.1053\/j.jfas.2020.10.002"},{"key":"7473_CR55","doi-asserted-by":"crossref","unstructured":"Shi J, Liang G, Huang R, et al. 2018. Effects of bisphosphonates in preventing periprosthetic bone loss following total hip arthroplasty: a systematic review and meta-analysis. J Orthop Surg Res 13(1).","DOI":"10.1186\/s13018-018-0918-7"},{"key":"7473_CR56","doi-asserted-by":"crossref","unstructured":"Su J, Wei Y, Li XM, et al. 2018. Efficacy of risedronate in improving bone mineral density in patients undergoing total hip arthroplasty A meta-analysis of randomized controlled trials. Medicine (United States) 97(51).","DOI":"10.1097\/MD.0000000000013346"},{"key":"7473_CR57","doi-asserted-by":"crossref","unstructured":"Prieto-Alhambra D, Javaid MK, Judge A, et al. 2011. Bisphosphonate use and risk of post-operative fracture among patients undergoing a total knee replacement for knee osteoarthritis: a propensity score analysis. Osteoporosis International 22(5).","DOI":"10.1007\/s00198-010-1368-1"},{"key":"7473_CR58","doi-asserted-by":"crossref","unstructured":"Robbins J, Riedl M, Matsumoto T, et al. 2014. Biomechanical comparison of prophylactic medial malleolar fixation in total ankle arthroplasty. J Surg Orthop Adv 23(4).","DOI":"10.3113\/JSOA.2014.0189"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-025-07473-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00198-025-07473-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-025-07473-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T14:26:33Z","timestamp":1747664793000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00198-025-07473-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,4]]},"references-count":58,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["7473"],"URL":"https:\/\/doi.org\/10.1007\/s00198-025-07473-6","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,4]]},"assertion":[{"value":"1 October 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 April 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"None.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}