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General ethics approval for the use of these cohorts is also given by the University of Sheffield. Participant data will be stored in coded, de-identified form. Only summary statistics and aggregate data will be published, not allowing for identification of individual study participants.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"NC Harvey has received consultancy\/lecture fees\/honoraria\/grant funding from Alliance for Better Bone Health, Amgen, MSD, Eli Lilly, Radius Health, Servier, Shire, UCB, Consilient Healthcare, Kyowa Kirin, Echolight, Theramex and Internis Pharma. JA Kanis led the team that developed FRAX as director of the WHO Collaborating Centre for Metabolic Bone Diseases. EV McCloskey, WD Leslie, M. Lorentzon, NC Harvey, E. Liu, L. Vandenput and H. Johansson are members of the FRAX team. JA Kanis, NC Harvey, and EV McCloskey are members of the advisory body to the National Osteoporosis Guideline Group. JA Kanis reports no additional competing interests. M. Lorentzon has received lecture fees from Amgen, Lilly, Meda, Gedeon Richter, Medison Pharma, UCB Pharma and consulting fees from Amgen, Radius Health, UCB Pharma, Medac AB, Parexel International, all outside the presented work. EV McCloskey has received consultancy\/lecture fees\/grant funding\/honoraria from AgNovos, Amgen, AstraZeneca, Consilient Healthcare, Fresenius Kabi, Gilead, GSK, Hologic, Internis, Lilly, Merck, Novartis, Pfizer, Radius Health, Redx Oncology, Roche, Sanofi Aventis, UCB, ViiV, Warner Chilcott and I3 Innovus. ES Orwoll reports consulting fees from Angios, Biocon, Radius, and Bayer.","order":2,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}