{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T23:23:56Z","timestamp":1787181836293,"version":"build-2736575974"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["U01AR069869"],"award-info":[{"award-number":["U01AR069869"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020400","name":"Clinical and Translational Science Center, Weill Cornell Medical College","doi-asserted-by":"publisher","award":["UL1TR002384"],"award-info":[{"award-number":["UL1TR002384"]}],"id":[{"id":"10.13039\/100020400","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Osteoporos Int"],"DOI":"10.1007\/s00198-026-08176-2","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T22:36:08Z","timestamp":1787178968000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Abaloparatide and pelvic fracture healing: a phase 2 randomized placebo-controlled trial"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8593-343X","authenticated-orcid":false,"given":"Jeri W.","family":"Nieves","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Cosman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"McMahon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather","family":"Berman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger J.","family":"Bartolotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Jacob","family":"Kazam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Hentschel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Egol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Forsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Shan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Eun","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,20]]},"reference":[{"key":"8176_CR1","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s00198-022-06636-z","volume":"34","author":"ML Alvarez-Nebreda","year":"2023","unstructured":"Alvarez-Nebreda ML, Weaver MJ, Uribe-Leitz T et al (2023) Epidemiology of pelvic and acetabular fractures in the USA from 2007 to 2014. Osteoporos Int 34:527\u2013537. https:\/\/doi.org\/10.1007\/s00198-022-06636-z","journal-title":"Osteoporos Int"},{"key":"8176_CR2","doi-asserted-by":"publisher","first-page":"213","DOI":"10.2106\/JBJS.20.00738","volume":"103","author":"CT Smith","year":"2021","unstructured":"Smith CT, Barton DW, Piple AS, Carmouche JJ (2021) Pelvic fragility fractures: an opportunity to improve the undertreatment of osteoporosis. J Bone Joint Surg Am 103:213\u2013218. https:\/\/doi.org\/10.2106\/JBJS.20.00738","journal-title":"J Bone Joint Surg Am"},{"key":"8176_CR3","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1007\/s00198-021-05848-z","volume":"32","author":"O Sahota","year":"2021","unstructured":"Sahota O, van Berkel D, Ong T et al (2021) Pelvic fragility fractures-the forgotten osteoporotic fracture! Osteoporos Int 32:785\u2013786. https:\/\/doi.org\/10.1007\/s00198-021-05848-z","journal-title":"Osteoporos Int"},{"key":"8176_CR4","doi-asserted-by":"publisher","first-page":"1789","DOI":"10.1002\/jbmr.3116","volume":"32","author":"S Andrich","year":"2017","unstructured":"Andrich S, Haastert B, Neuhaus E et al (2017) Excess mortality after pelvic fractures among older people. J Bone Miner Res 32:1789\u20131801. https:\/\/doi.org\/10.1002\/jbmr.3116","journal-title":"J Bone Miner Res"},{"key":"8176_CR5","doi-asserted-by":"publisher","first-page":"2797","DOI":"10.1007\/s00198-012-1907-z","volume":"23","author":"D Prieto-Alhambra","year":"2012","unstructured":"Prieto-Alhambra D, Avil\u00e9s FF, Judge A et al (2012) Burden of pelvis fracture: a population-based study of incidence, hospitalisation and mortality. Osteoporos Int 23:2797\u20132803. https:\/\/doi.org\/10.1007\/s00198-012-1907-z","journal-title":"Osteoporos Int"},{"key":"8176_CR6","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1007\/s10195-012-0182-2","volume":"13","author":"M Alnaib","year":"2012","unstructured":"Alnaib M, Waters S, Shanshal Y et al (2012) Combined pubic rami and sacral osteoporotic fractures: a prospective study. J Orthop Traumatol 13:97\u2013103. https:\/\/doi.org\/10.1007\/s10195-012-0182-2","journal-title":"J Orthop Traumatol"},{"key":"8176_CR7","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s00223-012-9587-4","volume":"90","author":"J Goldhahn","year":"2012","unstructured":"Goldhahn J, F\u00e9ron J-M, Kanis J et al (2012) Implications for fracture healing of current and new osteoporosis treatments: an ESCEO consensus paper. Calcif Tissue Int 90:343\u2013353. https:\/\/doi.org\/10.1007\/s00223-012-9587-4","journal-title":"Calcif Tissue Int"},{"key":"8176_CR8","doi-asserted-by":"publisher","first-page":"1022","DOI":"10.1002\/jbmr.2424","volume":"30","author":"CM Murphy","year":"2015","unstructured":"Murphy CM, Schindeler A, Cantrill LC et al (2015) PTH(1\u201334) treatment increases bisphosphonate turnover in fracture repair in rats. J Bone Miner Res 30:1022\u20131029. https:\/\/doi.org\/10.1002\/jbmr.2424","journal-title":"J Bone Miner Res"},{"issue":"Suppl 1","key":"8176_CR9","doi-asserted-by":"publisher","first-page":"S54","DOI":"10.1016\/S0020-1383(13)70013-5","volume":"44","author":"L Pietrogrande","year":"2013","unstructured":"Pietrogrande L, Raimondo E (2013) Teriparatide in the treatment of non-unions: scientific and clinical evidences. Injury 44(Suppl 1):S54-57. https:\/\/doi.org\/10.1016\/S0020-1383(13)70013-5","journal-title":"Injury"},{"key":"8176_CR10","doi-asserted-by":"publisher","first-page":"404","DOI":"10.1359\/jbmr.090731","volume":"25","author":"P Aspenberg","year":"2010","unstructured":"Aspenberg P, Genant HK, Johansson T et al (2010) Teriparatide for acceleration of fracture repair in humans: a prospective, randomized, double-blind study of 102 postmenopausal women with distal radial fractures. J Bone Miner Res 25:404\u2013414. https:\/\/doi.org\/10.1359\/jbmr.090731","journal-title":"J Bone Miner Res"},{"key":"8176_CR11","doi-asserted-by":"publisher","first-page":"E1464","DOI":"10.1097\/BRS.0b013e31826ca2a8","volume":"37","author":"S Ohtori","year":"2012","unstructured":"Ohtori S, Inoue G, Orita S et al (2012) Teriparatide accelerates lumbar posterolateral fusion in women with postmenopausal osteoporosis: prospective study. Spine (Phila Pa 1976) 37:E1464-1468. https:\/\/doi.org\/10.1097\/BRS.0b013e31826ca2a8","journal-title":"Spine (Phila Pa 1976)"},{"key":"8176_CR12","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1002\/jbmr.3067","volume":"32","author":"J Malouf-Sierra","year":"2017","unstructured":"Malouf-Sierra J, Tarantino U, Garc\u00eda-Hern\u00e1ndez PA et al (2017) Effect of teriparatide or risedronate in elderly patients with a recent pertrochanteric hip fracture: final results of a 78-week randomized clinical trial. J Bone Miner Res 32:1040\u20131051. https:\/\/doi.org\/10.1002\/jbmr.3067","journal-title":"J Bone Miner Res"},{"key":"8176_CR13","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.2106\/JBJS.J.01379","volume":"93","author":"P Peichl","year":"2011","unstructured":"Peichl P, Holzer LA, Maier R, Holzer G (2011) Parathyroid hormone 1-84 accelerates fracture-healing in pubic bones of elderly osteoporotic women. J Bone Joint Surg Am 93:1583\u20131587. https:\/\/doi.org\/10.2106\/JBJS.J.01379","journal-title":"J Bone Joint Surg Am"},{"key":"8176_CR14","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1007\/s00198-021-05847-0","volume":"32","author":"K Eastman","year":"2021","unstructured":"Eastman K, Gerlach M, Piec I et al (2021) Effectiveness of parathyroid hormone (PTH) analogues on fracture healing: a meta-analysis. Osteoporos Int 32:1531\u20131546. https:\/\/doi.org\/10.1007\/s00198-021-05847-0","journal-title":"Osteoporos Int"},{"key":"8176_CR15","doi-asserted-by":"publisher","first-page":"182","DOI":"10.5371\/hp.2020.32.4.182","volume":"32","author":"NH Moon","year":"2020","unstructured":"Moon NH, Jang JH, Shin WC, Jung SJ (2020) Effects of teriparatide on treatment outcomes in osteoporotic hip and pelvic bone fractures: meta-analysis and systematic review of randomized controlled trials. Hip Pelvis 32:182\u2013191. https:\/\/doi.org\/10.5371\/hp.2020.32.4.182","journal-title":"Hip Pelvis"},{"key":"8176_CR16","doi-asserted-by":"publisher","first-page":"5914502","DOI":"10.1155\/2020\/5914502","volume":"2020","author":"S Han","year":"2020","unstructured":"Han S, Wen S-M, Zhao Q-P et al (2020) The efficacy of teriparatide in improving fracture healing in hip fractures: a systematic review and meta-analysis. Biomed Res Int 2020:5914502. https:\/\/doi.org\/10.1155\/2020\/5914502","journal-title":"Biomed Res Int"},{"key":"8176_CR17","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1007\/s00198-021-06065-4","volume":"33","author":"JW Nieves","year":"2022","unstructured":"Nieves JW, Cosman F, McMahon D et al (2022) Teriparatide and pelvic fracture healing: a phase 2 randomized controlled trial. Osteoporos Int 33:239\u2013250. https:\/\/doi.org\/10.1007\/s00198-021-06065-4","journal-title":"Osteoporos Int"},{"key":"8176_CR18","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1080\/17453674.2018.1523771","volume":"89","author":"M Bernhardsson","year":"2018","unstructured":"Bernhardsson M, Aspenberg P (2018) Abaloparatide versus teriparatide: a head to head comparison of effects on fracture healing in mouse models. Acta Orthop 89:674\u2013677. https:\/\/doi.org\/10.1080\/17453674.2018.1523771","journal-title":"Acta Orthop"},{"key":"8176_CR19","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1002\/jor.24254","volume":"37","author":"B Lanske","year":"2019","unstructured":"Lanske B, Chandler H, Pierce A et al (2019) Abaloparatide, a PTH receptor agonist with homology to PTHrP, enhances callus bridging and biomechanical properties in rats with femoral fracture. J Orthop Res 37:812\u2013820. https:\/\/doi.org\/10.1002\/jor.24254","journal-title":"J Orthop Res"},{"key":"8176_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2024.117056","volume":"182","author":"A Makino","year":"2024","unstructured":"Makino A, Hasegawa T, Yamamoto T et al (2024) Abaloparatide promotes bone repair of vertebral defects in ovariectomized rats by increasing bone formation. Bone 182:117056. https:\/\/doi.org\/10.1016\/j.bone.2024.117056","journal-title":"Bone"},{"key":"8176_CR21","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1097\/BRS.0000000000004452","volume":"47","author":"KW Morse","year":"2022","unstructured":"Morse KW, Moore H, Kumagai H et al (2022) Abaloparatide enhances fusion and bone formation in a rabbit spinal arthrodesis model. Spine (Phila Pa 1976) 47:1607\u20131612. https:\/\/doi.org\/10.1097\/BRS.0000000000004452","journal-title":"Spine (Phila Pa 1976)"},{"key":"8176_CR22","doi-asserted-by":"publisher","DOI":"10.1016\/j.bonr.2021.101146","volume":"15","author":"JA Nelson","year":"2021","unstructured":"Nelson JA, Gavin KJ (2021) The use of abaloparatide to treat nonunion following dorsal closing wedge osteotomy for Freiberg\u2019s disease: a case report. Bone Rep 15:101146. https:\/\/doi.org\/10.1016\/j.bonr.2021.101146","journal-title":"Bone Rep"},{"key":"8176_CR23","doi-asserted-by":"publisher","first-page":"516","DOI":"10.1097\/BOT.0000000000000390","volume":"29","author":"J Litrenta","year":"2015","unstructured":"Litrenta J, Tornetta P, Mehta S et al (2015) Determination of radiographic healing: an assessment of consistency using RUST and modified RUST in metadiaphyseal fractures. J Orthop Trauma 29:516\u2013520. https:\/\/doi.org\/10.1097\/BOT.0000000000000390","journal-title":"J Orthop Trauma"},{"key":"8176_CR24","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1007\/s00256-018-3051-0","volume":"48","author":"JS Fisher","year":"2019","unstructured":"Fisher JS, Kazam JJ, Fufa D, Bartolotta RJ (2019) Radiologic evaluation of fracture healing. Skeletal Radiol 48:349\u2013361. https:\/\/doi.org\/10.1007\/s00256-018-3051-0","journal-title":"Skeletal Radiol"},{"key":"8176_CR25","unstructured":"Jensen MP, Karoly P (2001) Self-report scales and procedures for assessing pain in adults. Handbook of pain assessment, 2nd ed. The Guilford Press, New York, NY, US, pp 15\u201334"},{"key":"8176_CR26","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1023\/A:1026240322240","volume":"4","author":"PV Butler","year":"1997","unstructured":"Butler PV (1997) Linear analogue self-assessment and procrustean measurement: a critical review of visual analogue scaling in pain assessment. J Clin Psychol Med Settings 4:111\u2013129. https:\/\/doi.org\/10.1023\/A:1026240322240","journal-title":"J Clin Psychol Med Settings"},{"key":"8176_CR27","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1097\/BRS.0b013e31815e3a10","volume":"33","author":"RWJG Ostelo","year":"2008","unstructured":"Ostelo RWJG, Deyo RA, Stratford P et al (2008) Interpreting change scores for pain and functional status in low back pain: towards international consensus regarding minimal important change. Spine (Phila Pa 1976) 33:90\u201394. https:\/\/doi.org\/10.1097\/BRS.0b013e31815e3a10","journal-title":"Spine (Phila Pa 1976)"},{"key":"8176_CR28","doi-asserted-by":"publisher","first-page":"M85","DOI":"10.1093\/geronj\/49.2.m85","volume":"49","author":"JM Guralnik","year":"1994","unstructured":"Guralnik JM, Simonsick EM, Ferrucci L et al (1994) A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. J Gerontol 49:M85-94. https:\/\/doi.org\/10.1093\/geronj\/49.2.m85","journal-title":"J Gerontol"},{"key":"8176_CR29","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1016\/s0895-4356(02)00436-5","volume":"55","author":"GV Ostir","year":"2002","unstructured":"Ostir GV, Volpato S, Fried LP et al (2002) Reliability and sensitivity to change assessed for a summary measure of lower body function: results from the Women\u2019s Health and Aging Study. J Clin Epidemiol 55:916\u2013921. https:\/\/doi.org\/10.1016\/s0895-4356(02)00436-5","journal-title":"J Clin Epidemiol"},{"key":"8176_CR30","doi-asserted-by":"publisher","first-page":"484","DOI":"10.1007\/BF03324735","volume":"19","author":"JW Nieves","year":"2007","unstructured":"Nieves JW, Li T, Zion M et al (2007) The clinically meaningful change in physical performance scores in an elderly cohort. Aging Clin Exp Res 19:484\u2013491. https:\/\/doi.org\/10.1007\/BF03324735","journal-title":"Aging Clin Exp Res"},{"key":"8176_CR31","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1111\/j.1532-5415.1991.tb01616.x","volume":"39","author":"D Podsiadlo","year":"1991","unstructured":"Podsiadlo D, Richardson S (1991) The timed \u201cUp & Go\u201d: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 39:142\u2013148. https:\/\/doi.org\/10.1111\/j.1532-5415.1991.tb01616.x","journal-title":"J Am Geriatr Soc"},{"key":"8176_CR32","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1007\/s00198-020-05681-w","volume":"32","author":"BaM Larsson","year":"2021","unstructured":"Larsson BaM, Johansson L, Johansson H et al (2021) The timed up and go test predicts fracture risk in older women independently of clinical risk factors and bone mineral density. Osteoporos Int 32:75\u201384. https:\/\/doi.org\/10.1007\/s00198-020-05681-w","journal-title":"Osteoporos Int"},{"key":"8176_CR33","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1177\/026921559701100105","volume":"11","author":"K Hachisuka","year":"1997","unstructured":"Hachisuka K, Ogata H, Ohkuma H et al (1997) Test-retest and inter-method reliability of the self-rating Barthel Index. Clin Rehabil 11:28\u201335. https:\/\/doi.org\/10.1177\/026921559701100105","journal-title":"Clin Rehabil"},{"key":"8176_CR34","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1097\/00005650-198807000-00007","volume":"26","author":"AL Stewart","year":"1988","unstructured":"Stewart AL, Hays RD, Ware JE (1988) The MOS short-form general health survey. Reliability and validity in a patient population. Med Care 26:724\u2013735. https:\/\/doi.org\/10.1097\/00005650-198807000-00007","journal-title":"Med Care"},{"key":"8176_CR35","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1097\/00005650-199206000-00002","volume":"30","author":"JE Ware","year":"1992","unstructured":"Ware JE, Sherbourne CD (1992) The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 30:473\u2013483","journal-title":"Med Care"},{"key":"8176_CR36","unstructured":"Pirie W (1983) Jonckheere tests for ordered alternatives. In: Kotz S, Johnson NL, Read CB (eds) Encyclopedia of statistical sciences. John Wiley & Sons, New York, pp 315\u2013318"},{"key":"8176_CR37","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1007\/s00198-024-07059-8","volume":"35","author":"M Chandran","year":"2024","unstructured":"Chandran M, Akesson KE, Javaid MK et al (2024) Impact of osteoporosis and osteoporosis medications on fracture healing: a narrative review. Osteoporos Int 35:1337\u20131358. https:\/\/doi.org\/10.1007\/s00198-024-07059-8","journal-title":"Osteoporos Int"},{"key":"8176_CR38","doi-asserted-by":"publisher","first-page":"3309","DOI":"10.1007\/s00198-016-3651-2","volume":"27","author":"Y Zhao","year":"2016","unstructured":"Zhao Y, Xue R, Shi N et al (2016) Aggravation of spinal cord compromise following new osteoporotic vertebral compression fracture prevented by teriparatide in patients with surgical contraindications. Osteoporos Int 27:3309\u20133317. https:\/\/doi.org\/10.1007\/s00198-016-3651-2","journal-title":"Osteoporos Int"},{"issue":"22","key":"8176_CR39","doi-asserted-by":"publisher","first-page":"1868","DOI":"10.2106\/JBJS.15.01217","volume":"98","author":"P Aspenberg","year":"2016","unstructured":"Aspenberg P, Malouf J, Tarantino U, Garc\u00eda-Hern\u00e1ndez PA, Corradini C, Overgaard S et al (2016) Effects of teriparatide compared with risedronate on recovery after pertrochanteric hip fracture: results of a randomized, active-controlled, double-blind clinical trial at 26 weeks. J Bone Joint Surg Am 98(22):1868\u201318780","journal-title":"J Bone Joint Surg Am"},{"key":"8176_CR40","volume":"2015","author":"T-W Huang","year":"2015","unstructured":"Huang T-W, Yang T-Y, Huang K-C, Peng K-T, Lee MS, Hsu R-W (2015) Effect of teriparatide on unstable pertrochanteric fractures. Biomed Res Int 2015:568390","journal-title":"Biomed Res Int"},{"key":"8176_CR41","doi-asserted-by":"publisher","first-page":"100217","DOI":"10.1016\/j.bonr.2019.100217","volume":"11","author":"K Shigenobu","year":"2019","unstructured":"Shigenobu K, Hashimoto T, Kanayama M, Ohha H, Yamane S (2019) The efficacy of osteoporotic treatment in patients with new spinal vertebral compression fracture pain, ADL, QOL, bone metabolism and fracture-healing - in comparison with weekly teriparatide with bisphosphonate. Bone Rep 11:100217","journal-title":"Bone Rep"},{"key":"8176_CR42","doi-asserted-by":"publisher","first-page":"79","DOI":"10.3109\/17453674.2015.1073050","volume":"87","author":"T Johansson","year":"2016","unstructured":"Johansson T (2016) PTH 1\u201334 (teriparatide) may not improve healing in proximal humerus fractures. Acta Orthop 87:79\u201382. https:\/\/doi.org\/10.3109\/17453674.2015.1073050","journal-title":"Acta Orthop"},{"key":"8176_CR43","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1007\/s11999-015-4669-z","volume":"474","author":"M Bhandari","year":"2016","unstructured":"Bhandari M, Jin L, See K et al (2016) Does teriparatide improve femoral neck fracture healing: results from a randomized placebo-controlled trial. Clin Orthop Relat Res 474:1234\u20131244. https:\/\/doi.org\/10.1007\/s11999-015-4669-z","journal-title":"Clin Orthop Relat Res"},{"issue":"8","key":"8176_CR44","doi-asserted-by":"publisher","first-page":"693","DOI":"10.2106\/JBJS.19.00790","volume":"102","author":"EH Schemitsch","year":"2020","unstructured":"Schemitsch EH, Miclau T, Karachalios T, Nowak LL, Sancheti P, Poolman RW, Caminis J, Daizadeh N, Dent-Acosta RE, Egbuna O, Chines A, Maddox J, Grauer A, Bhandari M (2020) A randomized, placebo-controlled study of romosozumab for the treatment of hip fractures. J Bone Joint Surg Am 102(8):693\u2013702. https:\/\/doi.org\/10.2106\/JBJS.19.00790","journal-title":"J Bone Joint Surg Am"},{"issue":"16","key":"8176_CR45","doi-asserted-by":"publisher","first-page":"1416","DOI":"10.2106\/JBJS.19.01008","volume":"102","author":"M Bhandari","year":"2020","unstructured":"Bhandari M, Schemitsch EH, Karachalios T, Sancheti P, Poolman RW, Caminis J, Daizadeh N, Dent-Acosta RE, Egbuna O, Chines A, Miclau T (2020) Romosozumab in skeletally mature adults with a fresh unilateral tibial diaphyseal fracture: a randomized phase-2 study. J Bone Joint Surg Am 102(16):1416\u20131426. https:\/\/doi.org\/10.2106\/JBJS.19.01008","journal-title":"J Bone Joint Surg Am"}],"container-title":["Osteoporosis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-026-08176-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00198-026-08176-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00198-026-08176-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T22:36:10Z","timestamp":1787178970000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00198-026-08176-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":45,"alternative-id":["8176"],"URL":"https:\/\/doi.org\/10.1007\/s00198-026-08176-2","relation":{},"ISSN":["0937-941X","1433-2965"],"issn-type":[{"value":"0937-941X","type":"print"},{"value":"1433-2965","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,20]]},"assertion":[{"value":"27 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":2,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Jeri W. Nieves has received research funding and study drug for an NIH trial from Radius. Felicia Cosman has received research funding, consulting, and lecture fees from Radius; received consulting, advising, and lecture fees from Amgen; and received consulting fees from Enterabio, Theramex, UCB, Biocon, and Curateq. Joseph Lane consults for Mesentech, Radius Health, Terumo BCT, Kuras, and ON Foundation and received grant support from Merck and Novartis. Kenneth Egol consults for Exactech and receives research support from Depuy Synthes. Donald McMahon, Heather Berman, Isabelle Henstschel, Roger J. Bartolotta, J. Jacob Kazam, David Forsh, Yuan-Shan Zhu, and Jae Eun Yoo have nothing to declare.","order":3,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}