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Chromosomal mutations are responsible for resistance to ceftriaxone and cefepime. The possibility of mutations in the gene encoding beta-lactamase (\n                      <jats:italic>bla<\/jats:italic>\n                      <jats:sub>TEM<\/jats:sub>\n                      ) in the penicillinase plasmid may also turn out to be a serious threat.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The occurrence of resistance encoded on penicillinase plasmid has been investigated. For this purpose, the susceptibility of bacteria was determined and the gene for resistance to beta-lactams as well as the plasmids themselves was typed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 333 strains tested, 21 (6.3%) had the beta-lactamase gene and produced penicillinase. Two of the beta-lactamase: TEM-1 and TEM-135 occurred among the tested strains of\n                      <jats:italic>N. gonorrhoeae<\/jats:italic>\n                      . Most of the known penicillinase plasmid types of\n                      <jats:italic>N. gonorrhoeae<\/jats:italic>\n                      were demonstrated: the Asian, the African, the Toronto\/Rio plasmids and Australian variants.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      In the first 3 years, TEM-1 beta-lactamases dominated in\n                      <jats:italic>N. gonorrhoeae<\/jats:italic>\n                      , which were replaced by TEM-135 in the following years of the study. Not all molecular methods are capable of varying the types of penicillinase plasmids. A particularly noteworthy observation is the fact that the Australia-type of penicillinase plasmid (3270\u00a0bp) was identified for the first time in Europe, and the second time in the world.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00203-021-02623-w","type":"journal-article","created":{"date-parts":[[2022,1,9]],"date-time":"2022-01-09T02:02:12Z","timestamp":1641693732000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Penicillinase plasmid Australia type in Neisseria gonorrhoeae isolated in Poland"],"prefix":"10.1007","volume":"204","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0820-0149","authenticated-orcid":false,"given":"Szymon","family":"Walter de Walthoffen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,1,9]]},"reference":[{"key":"2623_CR1","doi-asserted-by":"publisher","first-page":"443","DOI":"10.3329\/jhpn.v28i5.6152","volume":"28","author":"MU Ahmed","year":"2010","unstructured":"Ahmed MU, Chawdhury FAH, Hossain M et al (2010) Monitoring antimicrobial susceptibility of Neisseria gonorrhoeae isolated from Bangladesh during 1997\u20132006: emergence and pattern of drug-resistant isolates. 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