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It is a pathogenic agent with potential health hazards related to diverse diseases, especially digestive diseases, such as chronic gastritis, peptic ulcer, and gastric carcinoma. In clinical, antibiotics are commonly applied in eradication therapy of\u00a0<jats:italic>H. pylori<\/jats:italic>. However, the increase in antibiotic resistance and side effects has induced the failure of eradication therapy. Recent studies have shown that probiotic supplementation has promising application prospects. It can restore the gastrointestinal microbiota balance and prevent dysbacteriosis caused by antibiotics. Furthermore, it has been reported to have direct or indirect inhibitory effects on\u00a0<jats:italic>H. pylori<\/jats:italic>. Probiotics may have a beneficial effect on\u00a0<jats:italic>H. pylori<\/jats:italic>\u00a0eradication. 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