{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:15:50Z","timestamp":1786979750085,"version":"build-2736575974"},"reference-count":52,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T00:00:00Z","timestamp":1676592000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Arch Microbiol"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1007\/s00203-023-03426-x","type":"journal-article","created":{"date-parts":[[2023,2,17]],"date-time":"2023-02-17T06:04:03Z","timestamp":1676613843000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["In silico molecular modelling studies and antibiofilm efficacy of shikonin against Candida albicans: mechanistic insight"],"prefix":"10.1007","volume":"205","author":[{"given":"Kirandeep","family":"Kaur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atamjit","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajanbir","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harneetpal","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajinder","family":"Kaur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saroj","family":"Arora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neena","family":"Bedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,17]]},"reference":[{"issue":"14","key":"3426_CR1","doi-asserted-by":"publisher","first-page":"2801","DOI":"10.3390\/app9142801","volume":"9","author":"S Achinas","year":"2019","unstructured":"Achinas S, Charalampogiannis N, Euverink GJW (2019) A brief recap of microbial adhesion and biofilms. Appl Sci 9(14):2801","journal-title":"Appl Sci"},{"issue":"1","key":"3426_CR2","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1007\/s11046-007-9077-9","volume":"165","author":"V Agarwal","year":"2008","unstructured":"Agarwal V, Lal P, Pruthi V (2008) Prevention of Candida albicans biofilm by plant oils. Mycopathologia 165(1):13\u201319","journal-title":"Mycopathologia"},{"issue":"21","key":"3426_CR3","first-page":"15","volume":"6","author":"FL Aguiar","year":"2020","unstructured":"Aguiar FL, Santos NC, de Paula Cavalcante CS, Andreu D, Baptista GR, Gon\u00e7alves S (2020) Antibiofilm activity on candida albicans and mechanism of action on biomembrane models of the antimicrobial peptide. Int J Mol Sci 6(21):15\u201334","journal-title":"Int J Mol Sci"},{"issue":"8","key":"3426_CR4","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1128\/AAC.44.8.2081-2085.2000","volume":"44","author":"BA Arthington-Skaggs","year":"2000","unstructured":"Arthington-Skaggs BA, Warnock DW, Morrison CJ (2000) Quantitation of Candida albicans ergosterol content improves the correlation between in vitro antifungal susceptibility test results and in vivo outcome after fluconazole treatment in a murine model of invasive candidiasis. Antimicrob Agents Chemother 44(8):2081\u20132085","journal-title":"Antimicrob Agents Chemother"},{"issue":"6","key":"3426_CR5","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.1002\/jhet.942","volume":"49","author":"AM Asiri","year":"2012","unstructured":"Asiri AM, Khan SA (2012) Synthesis, characterization, and in vitro antibacterial activities of macromolecules derived from bis-chalcone. J Heterocycl Chem 49(6):1434\u20131438","journal-title":"J Heterocycl Chem"},{"issue":"5","key":"3426_CR6","doi-asserted-by":"publisher","first-page":"8720","DOI":"10.1021\/acsomega.8b02481","volume":"4","author":"K Bhagat","year":"2019","unstructured":"Bhagat K, Bhagat J, Gupta MK, Singh JV, Gulati HK, Singh A, Kaur K, Kaur G, Sharma S, Rana A, Singh H (2019) Design, synthesis, antimicrobial evaluation, and molecular modeling studies of novel indolinedione\u2013coumarin molecular hybrids. ACS Omega 4(5):8720\u20138730","journal-title":"ACS Omega"},{"issue":"4","key":"3426_CR7","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3390\/jof3040057","volume":"3","author":"F Bongomin","year":"2017","unstructured":"Bongomin F, Gago S, Oladele RO, Denning DW (2017) Global and multi-national prevalence of fungal diseases\u2014estimate precision. J Fungus 3(4):57","journal-title":"J Fungus"},{"key":"3426_CR9","unstructured":"ChemDraw Ultra 6.0 and Chem3D Ultra (2013) Cambridge Soft Corporation, Cambridge, MA"},{"issue":"5","key":"3426_CR10","doi-asserted-by":"publisher","first-page":"2434","DOI":"10.1016\/S0006-3495(98)77951-2","volume":"74","author":"J Cladera","year":"1998","unstructured":"Cladera J, O\u2019Shea P (1998) Intramembrane molecular dipoles affect the membrane insertion and folding of a model amphiphilic peptide. Biophys J 74(5):2434\u20132442","journal-title":"Biophys J"},{"issue":"2","key":"3426_CR11","doi-asserted-by":"publisher","first-page":"154","DOI":"10.3390\/microorganisms8020154","volume":"8","author":"S Costa de Oliveira","year":"2020","unstructured":"Costa de Oliveira S, Rodrigues AG (2020) Candida albicans antifungal resistance and tolerance in bloodstream infections: the triad yeast-host-antifungal. Microorganisms 8(2):154","journal-title":"Microorganisms"},{"issue":"1","key":"3426_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s100960050001","volume":"19","author":"JA Crump","year":"2000","unstructured":"Crump JA, Collignon PJ (2000) Intravascular catheter-associated infections. Eur J Clin Microbiol Infect Dis 19(1):1\u20138","journal-title":"Eur J Clin Microbiol Infect Dis"},{"issue":"3","key":"3426_CR13","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3390\/pharmaceutics11030099","volume":"11","author":"G Cuddihy","year":"2019","unstructured":"Cuddihy G, Wasan EK, Di Y, Wasan KM (2019) The development of oral amphotericin B to treat systemic fungal and parasitic infections: has the myth been finally realized? Pharmaceutics 11(3):99","journal-title":"Pharmaceutics"},{"key":"3426_CR14","unstructured":"Dassault Systemes BIOVIA, Discovery Studio Modeling Environment; Release 2017, San Diego, Dassault Systems: 2016"},{"key":"3426_CR15","first-page":"e57127","volume":"132","author":"CM de Souza Silva","year":"2018","unstructured":"de Souza Silva CM, Guilhelmelli F, Zamith-Miranda D, de Oliveira MA, Nosanchuk JD, Silva-Pereira I, Albuquerque P (2018) Broth microdilution in vitro screening: an easy and fast method to detect new antifungal compounds. J vis Exp 132:e57127","journal-title":"J vis Exp"},{"issue":"5","key":"3426_CR17","doi-asserted-by":"publisher","first-page":"310","DOI":"10.1016\/j.micinf.2016.01.002","volume":"18","author":"M Gulati","year":"2016","unstructured":"Gulati M, Nobile CJ (2016) Candida albicans biofilms: development, regulation, and molecular mechanisms. Microbes Infect 18(5):310\u2013321","journal-title":"Microbes Infect"},{"key":"3426_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2019.104463","volume":"149","author":"C Guo","year":"2019","unstructured":"Guo C, He J, Song X, Tan L, Wang M, Jiang P, Li Y, Cao Z, Peng C (2019) Pharmacological properties and derivatives of shikonin\u2014A review in recent years. Pharmacol Res 149:104463","journal-title":"Pharmacol Res"},{"key":"3426_CR19","doi-asserted-by":"crossref","unstructured":"Hao B, Cheng S, Clancy CJ, Nguyen MH (2013) Caspofungin kills Candida albicans by causing both cellular apoptosis and necrosis. Antimicrob Agents Chemother. 57(1): 326\u2013332. https:\/\/www.rcsb.org\/structure\/5TZ1 (Accessed on 24\/05\/2022)","DOI":"10.1128\/AAC.01366-12"},{"key":"3426_CR20","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1007\/s12281-010-0018-6","volume":"4","author":"MD Johnson","year":"2010","unstructured":"Johnson MD, Perfect JR (2010) Use of antifungal combination therapy: agents, order, and timing. Curr Fungal Infect Rep 4:87\u201395","journal-title":"Curr Fungal Infect Rep"},{"issue":"8","key":"3426_CR21","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1016\/j.tim.2020.03.016","volume":"28","author":"L Karygianni","year":"2020","unstructured":"Karygianni L, Ren Z, Koo H, Thurnheer T (2020) Biofilm matrixome: extracellular components in structured microbial communities. Trends Microbiol 28(8):668\u2013681","journal-title":"Trends Microbiol"},{"issue":"4","key":"3426_CR22","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1016\/j.chmed.2022.08.001","volume":"14","author":"K Kaur","year":"2022","unstructured":"Kaur K, Sharma R, Singh A, Attri S, Arora S, Kaur S, Bedi N (2022) Pharmacological and analytical aspects of alkannin\/shikonin and their derivatives: an update from 2008 to 2022. Chin Herb Med 14(4):511\u2013527","journal-title":"Chin Herb Med"},{"issue":"12","key":"3426_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2018.e01067","volume":"4","author":"Z Khatoon","year":"2018","unstructured":"Khatoon Z, McTiernan CD, Suuronen EJ, Mah TF, Alarcon EI (2018) Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention. Heliyon 4(12):e01067","journal-title":"Heliyon"},{"issue":"2","key":"3426_CR24","first-page":"225-e15","volume":"26","author":"M Klepser","year":"2010","unstructured":"Klepser M (2010) The value of amphotericin B in the treatment of invasive fungal infections. J Crit Care 26(2):225-e15-225-e10","journal-title":"J Crit Care"},{"issue":"6","key":"3426_CR25","doi-asserted-by":"publisher","first-page":"1392","DOI":"10.1128\/AAC.41.6.1392","volume":"41","author":"ME Klepser","year":"1997","unstructured":"Klepser ME, Wolfe EJ, Jones RN, Nightingale CH, Pfaller MA (1997) Antifungal pharmacodynamic characteristics of fluconazole and amphotericin B tested against Candida albicans. Antimicrob Agents Chemother 41(6):1392\u20131395","journal-title":"Antimicrob Agents Chemother"},{"issue":"5","key":"3426_CR26","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1128\/AAC.42.5.1207","volume":"42","author":"ME Klepser","year":"1998","unstructured":"Klepser ME, Ernst EJ, Lewis RE, Ernst ME, Pfaller MA (1998) Influence of test conditions on antifungal time-kill curve results: proposal for standardized methods. Antimicrob Agents Chemother 42(5):1207\u20131212","journal-title":"Antimicrob Agents Chemother"},{"key":"3426_CR27","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1007\/978-1-61779-588-6_10","volume":"857","author":"I Kufareva","year":"2012","unstructured":"Kufareva I, Abagyan R (2012) Methods of protein structure comparison. Methods Mol Biol 857:231\u2013257","journal-title":"Methods Mol Biol"},{"key":"3426_CR28","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1007\/s12013-014-0083-5","volume":"70","author":"W Lan","year":"2014","unstructured":"Lan W, Wan S, Gu W, Wang H, Zhou S (2014) Mechanisms behind the inhibition of lung adenocarcinoma cell by shikonin. Cell Biochem Biophys 70:1459\u20131467","journal-title":"Cell Biochem Biophys"},{"key":"3426_CR29","unstructured":"Lead IT (2017) version 2.3.2; BioSolveIT GmbH, Sankt Augustin, Germany"},{"key":"3426_CR30","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1016\/j.cbi.2014.01.008","volume":"211","author":"MJ Lee","year":"2014","unstructured":"Lee MJ, Kao SH, Hunag JE, Sheu GT, Yeh CW, Hseu YC (2014) Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species. Chem Biol Interact 211:44\u201353","journal-title":"Chem Biol Interact"},{"issue":"12","key":"3426_CR31","doi-asserted-by":"publisher","first-page":"6016","DOI":"10.1128\/AAC.00499-13","volume":"57","author":"DD Li","year":"2013","unstructured":"Li DD, Xu Y, Zhang DZ, Quan H, Mylonakis E, Hu DD, Li MB, Zhao LX, Zhu LH, Wang Y, Jiang YY (2013) Fluconazole assists berberine to kill fluconazole-resistant Candida albicans. Antimicrob Agents Chemother 57(12):6016\u20136027","journal-title":"Antimicrob Agents Chemother"},{"key":"3426_CR32","first-page":"1","volume":"28","author":"ZJ Li","year":"2020","unstructured":"Li ZJ, Abula A, Abulizi A, Wang C, Dou Q, Maimaiti Y, Abudouaini A, Huo SX, Aibai S (2020) Ellagic acid inhibits trichophyton rubrum growth via affecting ergosterol biosynthesis and apoptotic induction. Evid Based Complementary Altern 28:1\u20138","journal-title":"Evid Based Complementary Altern"},{"key":"3426_CR33","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.ejphar.2011.02.043","volume":"658","author":"L Lu","year":"2011","unstructured":"Lu L, Qin A, Huang H, Zhou P, Zhang C, Liu N (2011) Shikonin extracted from medicinal Chinese herbs exerts anti-inflammatory effect via proteasome inhibition. Eur J Pharmacol 658:242\u2013247","journal-title":"Eur J Pharmacol"},{"issue":"6","key":"3426_CR34","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1080\/21505594.2016.1188236","volume":"7","author":"QZ Lv","year":"2016","unstructured":"Lv QZ, Yan L, Jiang YY (2016) The synthesis, regulation, and functions of sterols in Candida albicans: well-known but still lots to learn. Virulence 7(6):649\u2013659","journal-title":"Virulence"},{"key":"3426_CR35","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1586\/14787210.5.2.277","volume":"5","author":"AN Malani","year":"2007","unstructured":"Malani AN, Kauffman CA (2007) Candida urinary tract infections: treatment options. Expert Rev Anti Infect Ther 5:277\u2013284","journal-title":"Expert Rev Anti Infect Ther"},{"issue":"4","key":"3426_CR36","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1002\/bab.1116","volume":"60","author":"MJ Nirmala","year":"2013","unstructured":"Nirmala MJ, Mukherjee A, Chandrasekaran N (2013) Improved efficacy of fluconazole against candidiasis using bio-based microemulsion technique. Biotechnol Appl Biochem 60(4):417\u2013429","journal-title":"Biotechnol Appl Biochem"},{"issue":"20","key":"3426_CR37","doi-asserted-by":"publisher","first-page":"5110","DOI":"10.3390\/ijms20205110","volume":"20","author":"VK Pandey","year":"2019","unstructured":"Pandey VK, Srivastava KR, Ajmal G, Thakur VK, Gupta VK, Upadhyay SN, Mishra PK (2019) Differential susceptibility of catheter biomaterials to biofilm-associated infections and their remedy by drug-encapsulated eudragit RL100 nanoparticles. Int J Mol Sci 20(20):5110","journal-title":"Int J Mol Sci"},{"issue":"10","key":"3426_CR38","doi-asserted-by":"publisher","first-page":"5795","DOI":"10.1128\/AAC.03035-14","volume":"58","author":"G Pankey","year":"2014","unstructured":"Pankey G, Ashcraft D, Kahn H, Ismail A (2014) Time-kill assay and Etest evaluation for synergy with polymyxin B and fluconazole against Candida glabrata. Antimicrob Agents Chemother 58(10):5795\u20135800","journal-title":"Antimicrob Agents Chemother"},{"issue":"9","key":"3426_CR39","doi-asserted-by":"publisher","first-page":"1494","DOI":"10.1038\/nprot.2008.141","volume":"3","author":"CG Pierce","year":"2008","unstructured":"Pierce CG, Uppuluri P, Tristan AR, Wormley FL, Mowat E, Ramage G, Lopez-Ribot JL (2008) A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing. Nat Protoc 3(9):1494\u20131500","journal-title":"Nat Protoc"},{"key":"3426_CR40","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1111\/j.1574-6968.2008.01292.x","volume":"287","author":"A Pompilio","year":"2008","unstructured":"Pompilio A, Piccolomini R, Picciani C, D\u2019Antonio D, Savini V, Di Bonaventura G (2008) Factors associated with adherence to and biofilm formation on polystyrene by Stenotrophomonas maltophilia: the role of cell surface hydrophobicity and motility. FEMS Microbiol Lett 287:41\u201347","journal-title":"FEMS Microbiol Lett"},{"issue":"12","key":"3426_CR41","doi-asserted-by":"publisher","first-page":"863","DOI":"10.1002\/pts.2687","volume":"35","author":"R Priyadarshi","year":"2022","unstructured":"Priyadarshi R, Rhim JW (2022) Shikonin: Extraction, properties and applications in active and intelligent packaging. Packag Technol Sci 35(12):863\u2013877","journal-title":"Packag Technol Sci"},{"issue":"11","key":"3426_CR42","doi-asserted-by":"publisher","first-page":"5459","DOI":"10.1128\/AEM.68.11.5459-5463.2002","volume":"68","author":"G Ramage","year":"2002","unstructured":"Ramage G, Saville SP, Wickes BL, L\u00f3pez-Ribot JL (2002) Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule. Appl Environ Microbiol 68(11):5459\u20135463","journal-title":"Appl Environ Microbiol"},{"key":"3426_CR43","doi-asserted-by":"publisher","first-page":"707","DOI":"10.1111\/j.1699-0463.1995.tb01427.x","volume":"103","author":"YH Samaranayake","year":"1995","unstructured":"Samaranayake YH, Wu PC, Samaranayake LP, So M (1995) Relationship between the cell surface hydrophobicity and adherence of Candida krusei and Candida albicans to epithelial and denture acrylic surfaces. APMIS 103:707\u2013713","journal-title":"APMIS"},{"issue":"6","key":"3426_CR44","doi-asserted-by":"publisher","first-page":"1274","DOI":"10.1007\/s00044-016-1550-x","volume":"25","author":"JM S\u00e1nchez-Calvo","year":"2016","unstructured":"S\u00e1nchez-Calvo JM, Barbero GR, Guerrero-V\u00e1squez G, Dur\u00e1n AG, Mac\u00edas M, Rodr\u00edguez-Iglesias MA, Molinillo JM, Mac\u00edas FA (2016) Synthesis, antibacterial and antifungal activities of naphthoquinone derivatives: a structure\u2013activity relationship study. Med Chem Res 25(6):1274\u20131285","journal-title":"Med Chem Res"},{"issue":"4","key":"3426_CR45","doi-asserted-by":"publisher","first-page":"6","DOI":"10.29245\/2689-9981\/2019\/4.1143","volume":"2","author":"PM Sawadogo","year":"2019","unstructured":"Sawadogo PM, Zida A, Sangar\u00e9 I, Guiguemd\u00e9 TK, Sanfo A, Idani M, Nacanabo H, Bamba S, Ou\u00e9draogo R, Guiguemd\u00e9 TR (2019) Genetic mutations conferring resistance to candida albicans to antifungal drugs: a global perspective and regional implications. J Infectiology & Epidemiol 2(4):6\u201312","journal-title":"J Infectiology & Epidemiol"},{"issue":"7","key":"3426_CR46","doi-asserted-by":"publisher","first-page":"11673","DOI":"10.1021\/acsomega.9b01109","volume":"4","author":"A Singh","year":"2019","unstructured":"Singh A, Singh JV, Rana A, Bhagat K, Gulati HK, Kumar R, Salwan R, Bhagat K, Kaur G, Singh N, Kumar R (2019) Monocarbonyl curcumin-based molecular hybrids as potent antibacterial agents. ACS Omega 4(7):11673\u201311684","journal-title":"ACS Omega"},{"issue":"20","key":"3426_CR47","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.bmcl.2020.127477","volume":"30","author":"A Singh","year":"2020","unstructured":"Singh A, Sharma S, Arora S, Attri S, Kaur P, Gulati HK, Bhagat K, Kumar N, Singh H, Singh JV, Bedi PMS (2020) New coumarin-benzotriazole based hybrid molecules as inhibitors of acetylcholinesterase and amyloid aggregation. Bioorg Med Chem Lett 30(20):1\u201310","journal-title":"Bioorg Med Chem Lett"},{"issue":"6","key":"3426_CR48","doi-asserted-by":"publisher","first-page":"1632","DOI":"10.1002\/ardp.202200033","volume":"355","author":"A Singh","year":"2022","unstructured":"Singh A, Heer S, Kaur K, Gulati HK, Kumar N, Sharma A, Singh JV, Bhagat K, Kaur G, Kaur K, Singh H (2022a) Design, synthesis, and biological evaluation of isatin-indole-3-carboxaldehyde hybrids as a new class of xanthine oxidase inhibitors. Arch Pharm 355(6):1632\u20131642","journal-title":"Arch Pharm"},{"issue":"2","key":"3426_CR49","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/ardp.202100368","volume":"355","author":"A Singh","year":"2022","unstructured":"Singh A, Kaur H, Arora S, Bedi PMS (2022b) Design, synthesis, and biological evaluation of novel morpholinated isatin\u2013quinoline hybrids as potent anti-breast cancer agents. Arch Pharm 355(2):1\u201312","journal-title":"Arch Pharm"},{"key":"3426_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2022.134456","volume":"1274","author":"A Singh","year":"2023","unstructured":"Singh A, Kaur K, Kaur H, Mohana P, Arora S, Bedi N, Chadha R, Bedi PMS (2023) Design, synthesis and biological evaluation of isatin-benzotriazole hybrids as new class of anti-Candida agents. J Mol Struct 1274:134456","journal-title":"J Mol Struct"},{"issue":"16","key":"3426_CR51","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/molecules26165008","volume":"26","author":"M Staniszewska","year":"2021","unstructured":"Staniszewska M, Kuryk \u0141, Gryciuk A, Kawalec J, Rogalska M, Baran J, \u0141ukowska-Chojnacka E, Kowalkowska A (2021) In Vitro Anti-Candida Activity and Action Mode of Benzoxazole Derivatives. Molecules 26(16):1\u201319","journal-title":"Molecules"},{"key":"3426_CR52","unstructured":"Wayne PA (2008) CLSI. Reference method for broth dilution antifungal susceptibility testing of yeasts, approved standard, CLSI Document M27-A3. Clinical Laboratory Standards Institute"},{"key":"3426_CR53","doi-asserted-by":"publisher","first-page":"2173","DOI":"10.3389\/fmicb.2016.02173","volume":"7","author":"SG Whaley","year":"2017","unstructured":"Whaley SG, Berkow EL, Rybak JM, Nishimoto AT, Barker KS, Rogers PD (2017) Azole antifungal resistance in Candida albicans and emerging non-albicans Candida species. Front Microbiol 7:2173","journal-title":"Front Microbiol"},{"issue":"4","key":"3426_CR54","doi-asserted-by":"publisher","first-page":"915","DOI":"10.1016\/j.idc.2018.06.009","volume":"32","author":"YM Wi","year":"2018","unstructured":"Wi YM, Patel R (2018) Understanding biofilms and novel approaches to the diagnosis, prevention, and treatment of medical device-associated infections. Infect Dis Clin 32(4):915\u2013929","journal-title":"Infect Dis Clin"}],"container-title":["Archives of Microbiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-023-03426-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00203-023-03426-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00203-023-03426-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,10]],"date-time":"2023-03-10T01:03:36Z","timestamp":1678410216000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00203-023-03426-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,17]]},"references-count":52,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["3426"],"URL":"https:\/\/doi.org\/10.1007\/s00203-023-03426-x","relation":{},"ISSN":["0302-8933","1432-072X"],"issn-type":[{"value":"0302-8933","type":"print"},{"value":"1432-072X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,17]]},"assertion":[{"value":"17 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 January 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 January 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 February 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}],"article-number":"93"}}