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Bacterial surface structures known as fimbriae or pili play a fundamental role in the early colonization stages by providing specificity or tropism. Among the various fimbrial families, the chaperone-usher family has been extensively studied due to its ubiquity, diversity, and abundance. This family is named after the components that facilitate their biogenesis. Type 1 fimbria and P pilus, two chaperone-usher fimbriae associated with urinary tract infections, have been thoroughly investigated and serve as prototypes that have laid the foundations for understanding the biogenesis of this fimbrial family. Additionally, the study of the mechanisms regulating their expression has also been a subject of great interest, revealing that the regulation of the expression of the genes encoding these structures is a complex and diverse process, involving both common global regulators and those specific to each operon.<\/jats:p>","DOI":"10.1007\/s00203-024-04092-3","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T14:02:18Z","timestamp":1723298538000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Type 1 fimbria and P pili: regulatory mechanisms of the prototypical members of the chaperone-usher fimbrial family"],"prefix":"10.1007","volume":"206","author":[{"given":"Mar\u00eda I.","family":"Isidro-Coxca","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"Ortiz-Jim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 L.","family":"Puente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,8,10]]},"reference":[{"issue":"6","key":"4092_CR1","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1111\/j.1365-2958.2008.06115.x","volume":"67","author":"A Aberg","year":"2008","unstructured":"Aberg A, Shingler V, Balsalobre C (2008) Regulation of the fimB promoter: a case of differential regulation by ppGpp and DksA in vivo. 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